| Run against | 11 |
| Join the cons | 13 |
| Come out against | 16 |
| Attempt to block | 16 |
| Complain about test material? | 29 |
| Antithetical | 12 |
| Directly across from | 20 |
| Antithesis | 10 |
| Top to bottom? | 14 |
| Night, to day | 13 |
| Night to day | 13 |
| For, for against | 16 |
| Black, to white | 15 |
| Antonym | 7 |
| The antis | 9 |
| Friendly side in a debate | 25 |
| Weigh heavily on | 16 |
| Weigh heavily upon | 18 |
| Make downtrodden | 16 |
| Crush the spirit | 16 |
| Put under the yoke | 18 |
| Keep down | 9 |
| Rule despotically | 17 |
| Lie heavily upon | 16 |
| Persecuted | 10 |
| Like people under a dictator | 28 |
| Daffy under Elmer's rule? | 29 |
| Antonyms: Abbr. | 15 |
| They may be polar (Abbr.) | 25 |
| Pos. and neg. | 13 |
| Plus and minus: Abbr. | 21 |
| They may be polar: Abbr. | 24 |
| Stop and go, e.g.: Abbr. | 24 |
| Sometimes they attract (Abbr.) | 30 |
| Sm. and lge., e.g. | 18 |
| Pos. and neg., e.g. | 19 |
| H and C, on faucets | 19 |
| Big and small, e.g.: Abbr. | 26 |
| Antonyms, for short | 19 |
| Antonyms, briefly | 17 |
| N followers | 11 |
| NR connection | 13 |
| N?R connection | 14 |
| N–R connection | 21 |
| N-R linkup | 10 |
| N-R link | 8 |
| N-R connectors | 14 |
| Quartet before S | 16 |
| Orthography quartet | 19 |
| N-S links | 9 |
| N-S go-between | 14 |
| N-S connection | 14 |
| N-S bridge | 10 |
| Her talk show was based in Chicago | 34 |
| O founder | 9 |
| Daytime TV staple | 17 |
| Big name in book clubs | 22 |
| Big name in daytime TV | 22 |
| Winfrey of TV | 13 |
| Noted book reader | 17 |
| First name in daytime TV | 24 |
| TV's Winfrey | 16 |
| Talk-show host Winfrey | 22 |
| Queen of Talk | 13 |
| Ms. Winfrey | 11 |
| Big-time talker | 15 |
| TV host Winfrey | 15 |
| Talk show tycoon | 16 |
| Sofia's portrayer in "The Color Purple" | 53 |
| Part of OWN | 11 |
| Host with a 276-car stunt | 25 |
| Daytime TV mogul | 16 |
| Book club name | 14 |
| "The Color Purple" star | 33 |
| TV talk tycoon | 14 |
| TV host with a book club | 24 |
| TV book club creator | 20 |
| The O behind OWN | 16 |
| The "O" of OWN | 24 |
| The "O" in O magazine | 31 |
| The ''O'' of O Magazine | 39 |
| Talk-show tycoon | 16 |
| Talk show ending in 2011 | 24 |
| She backed Barack | 17 |
| Producer, actress and host | 26 |
| Media mogul with a Presidential Medal of Freedom | 48 |
| Longtime talk show | 18 |
| Long-running talk show | 22 |
| Host with a book club | 21 |
| Head of Harpo Productions | 25 |
| Daytime talk show host | 22 |
| Daytime star | 12 |
| Daytime megastar | 16 |
| Celeb on Forbes' billionaire list | 37 |
| Bookish hostess | 15 |
| Billionaire with a book club | 28 |
| Billionaire talker | 18 |
| Big name on TV | 14 |
| Big name in TV | 14 |
| Winfrey who said "I still have my feet on the ground, I just wear better shoes" | 89 |