| Author who "a lot of us ... pick[ed] up ... when we were 17 or 18 and feeling misunderstood," per Obama | 113 |
| Author of "The Fountainhead" | 39 |
| African money | 13 |
| African gold field | 18 |
| 100 cents, in East London | 25 |
| 100 cents may equal one | 23 |
| 100 cents in Pretoria | 21 |
| 100 cents abroad | 16 |
| "The Virtue of Selfishness" author | 44 |
| "The Fountainhead" writer Ayn ___ | 43 |
| "The Fountainhead" writer | 35 |
| "Atlas Shrugged" writer Ayn | 37 |
| "Atlas Shrugged" author Ayn | 37 |
| ''The Fountainhead'' writer | 43 |
| Musical genre, briefly | 22 |
| Musical genre with soul | 23 |
| Motown music | 12 |
| What R. Kelly claims to "put the R in" | 48 |
| Usher's style | 17 |
| Usher's genre, familiarly | 29 |
| The music of Ray Charles, briefly | 33 |
| Soul predecessor | 16 |
| Soul ancestor | 13 |
| Smokey Robinson's music genre, for short | 44 |
| Rock forerunner, for short | 26 |
| Rihanna's music | 19 |
| Raphael Saadiq's genre | 26 |
| Musical genre, in brief | 23 |
| Musical genre, for short | 24 |
| Musical genre for Destiny's Child | 37 |
| Music genre, informally | 23 |
| Music genre suitable for this puzzle's theme | 48 |
| Music genre (Abbr.) | 19 |
| Music category, for short | 25 |
| Jazz/gospel outgrowth, familiarly | 33 |
| Jazz-influenced genre | 21 |
| Grammy category, for short | 26 |
| Genre influenced by jazz | 24 |
| Genre for Smokey Robinson | 25 |
| Genre for Alicia Keys | 21 |
| Funky musical genre, for short | 30 |
| Fats Domino's music, for short | 34 |
| Domino's delivery? | 22 |
| Domino fans like it | 19 |
| Brandy's music genre, briefly | 33 |
| Brandy style, briefly | 21 |
| Billboard chart category | 24 |
| B.B. King's specialty | 25 |
| Drug company dept. | 18 |
| Corporate planning dept. | 24 |
| New products div. | 17 |
| Department that creates products, for short | 43 |
| Corp. budget item | 17 |
| Source of many patents, briefly | 31 |
| Source of a company's new ideas | 35 |
| Some lab work, for short | 24 |
| Product testing division | 24 |
| Product design dept. | 20 |
| Pharmaceuticals co. division | 28 |
| Pharmaceutical company budget line generally dwarfed by ad expenditures: Abbr. | 78 |
| New product div. | 16 |
| Lab work (abbr.) | 16 |
| Lab dept. | 9 |
| Experimental division, for short | 32 |
| Early stage of industrial work, for short | 41 |
| Discovery/design dept. | 22 |
| Department with labs | 20 |
| Corporation div. | 16 |
| Corporate expense, for short | 28 |
| Corporate dept. that may include labs | 37 |
| Corp. creativity department | 27 |
| Corp. creative dept. | 20 |
| Co.'s arm for investigation-growth | 38 |
| Area of corporate investment, briefly | 37 |
| "Amazing" magician | 28 |
| The Amazing ___ (noted magician) | 32 |
| The Amazing ___ (magician) | 26 |
| Former Facebook marketing director Zuckerberg | 45 |
| Actress Oakes of "CHiPs" | 34 |
| "Amazing" magician famous for debunking | 49 |
| "Amazing" debunker of pseudoscience | 45 |
| Toronto-born magician | 21 |
| The Amazing ___, illusionist | 28 |
| The Amazing ___ (debunker of pseudoscience) | 43 |
| The Amazing ___ | 15 |
| Progressive political commentator Rhodes | 40 |
| Paranormal-claim debunker | 25 |
| Oakes of "CHiPs" | 26 |
| Magician James | 14 |
| Left-leaning talk show host Rhodes | 34 |
| James ___, paranormal debunker | 30 |
| CNN journalist Kaye | 19 |
| Amazing magician and debunker | 29 |
| "The Amazing" magician | 32 |
| "Conjuring" author James | 34 |
| "CHiPs" actress Oakes | 31 |
| "Amazing" paranormal debunker | 39 |
| "Amazing" magician famous for debunking unreasonable claims | 69 |
| "Amazing" magician and debunker | 41 |
| "Amazing" illusionist | 31 |