| Aspirin unit | 12 |
| Bolus | 5 |
| Vitamin unit | 12 |
| Medicinal morsel | 16 |
| Rx unit | 7 |
| Capsule | 7 |
| Aspirin tablet | 14 |
| Just what the doctor ordered, maybe | 35 |
| Aspirin form | 12 |
| Person who's hard to take | 29 |
| One aspirin | 11 |
| It might get popped in the mouth | 32 |
| It may be bitter or hard to swallow | 35 |
| It can be hard to swallow | 25 |
| Dosage, maybe | 13 |
| Disagreeable person | 19 |
| Difficult sort | 14 |
| Alternative to liquid medicine | 30 |
| Vitamin, usually | 16 |
| Vitamin tablet | 14 |
| Troche or bolus | 15 |
| Tiresome chap | 13 |
| The Jam "The Bitterest ___" | 37 |
| Term for a Nolan Ryan fastball | 30 |
| Tedious sort | 12 |
| Source of pep? | 14 |
| Prescription piece, perhaps | 27 |
| Pharmacy caplet | 15 |
| Party-pooper | 12 |
| One may be bitter | 17 |
| Medicine tablet | 15 |
| Medicine dose, perhaps | 22 |
| Medicine dose | 13 |
| Medicine ball? | 14 |
| Medicinal tablet | 16 |
| Medicinal dose | 14 |
| Item in a box with seven compartments, say | 42 |
| It's taken in for treatment | 31 |
| It might be hard to swallow | 27 |
| It may make you a better person | 31 |
| It may be bitter to swallow | 27 |
| It can make you feel better | 27 |
| It can be popped | 16 |
| Insufferable one | 16 |
| Headache relief, perhaps | 24 |
| Hard-to-tolerate sort | 21 |
| Hard-to-take person | 19 |
| Dose of medicine | 16 |
| Dosage, perhaps | 15 |
| Dislikable person: sl. | 22 |
| Dislikable person, in slang | 27 |
| Disagreeable person: Slang | 26 |
| Clump, as fleece | 16 |
| Caplet or gelcap | 16 |
| Caplet e.g. | 12 |
| Caplet | 6 |
| Cachou, e.g. | 12 |
| Beck cover "Leopard-Skin ___-Box Hat" | 47 |
| Apothecary inventory item | 25 |
| Alternative to a caplet | 23 |
| Alanis has a "Little" one | 35 |
| Alanis had a "Jagged Little" one | 42 |
| Column | 6 |
| Column supporting a building | 28 |
| Stalwart column | 15 |
| Ornamental column | 17 |
| Temple support | 14 |
| Society stalwart | 16 |
| Society mainstay | 16 |
| Shape of Lot's wife, saltwise | 33 |
| Parthenon supporter | 19 |
| Parthenon part | 14 |
| Obelisk, for instance | 21 |
| Notable one in a community | 26 |
| Decorative column | 17 |
| Community standout | 18 |
| Community mainstay | 18 |
| Arcade support | 14 |
| ___ of society | 14 |
| Battles between the FDA and drug companies? | 43 |
| Word with talk or fight | 23 |
| Down home? | 10 |
| Sleeper's headrest | 22 |
| Bolster, e.g. | 13 |
| Bed item | 8 |
| "___ Talk," Doris Day film | 36 |
| Word with hair or talk | 22 |
| Word with case or sham | 22 |
| Where one might have a sinking feeling | 38 |
| Sofa cushion | 12 |
| Headrest | 8 |
| Feather-filled item | 19 |
| Drooled-on thing, perhaps | 25 |
| Dormitory weapon | 16 |
| A case is often made for it | 27 |
| "___ Talk," 1959 film | 31 |
| They may be hard to swallow | 27 |
| Pharmacy supply | 15 |
| Pharmacy stock | 14 |
| Pharmaceutical output | 21 |