| State where Paul Newman was born | 32 |
| State of Grant and Taft | 23 |
| State formed from the Northwest Territory | 41 |
| State admitted in 1803 | 22 |
| Song Bernstein composed | 23 |
| Soap Box Derby championship state | 33 |
| So-called Mother of Presidents | 30 |
| So-called Birthplace of Aviation | 32 |
| Sherwood Anderson's state | 29 |
| Sherwood Anderson's "Winesburg, ___" | 50 |
| Sherwood Anderson's "Winesburg, _____" | 52 |
| Setting of the Pro Football Hall of Fame | 40 |
| Senator Voinovich's state | 29 |
| Sen. Metzenbaum's state | 27 |
| Sen. Glenn's home base | 26 |
| Sandusky's setting | 22 |
| Sandusky Bay site | 17 |
| Roy Rogers's home state | 27 |
| Roy Rogers' home state | 26 |
| Rock and Roll Hall of Fame's home | 37 |
| River through Wheeling | 22 |
| River through Pittsburgh | 24 |
| River through Kentucky, Pennsylvania, and West Virginia, among others | 69 |
| River that starts at Pittsburgh | 31 |
| River that forms at Pittsburgh | 30 |
| River that ends at Cairo | 24 |
| River out of Pittsburgh | 23 |
| River into which the Kentucky flows | 35 |
| River into which the Great Miami flows | 38 |
| River into which the Big Sandy flows | 36 |
| River forming the borders of parts of five states | 49 |
| Reds' state | 15 |
| Reds and Browns call it home | 28 |
| Pro Football Hall of Fame state | 31 |
| Perennial swing state | 21 |
| Perennial battleground state | 28 |
| Part of the Northwest Territory | 31 |
| Part of Northwest Territory | 27 |
| Parma's place | 17 |
| Parma setting | 13 |
| Paducah river | 13 |
| Pa. river | 9 |
| OSU segment | 11 |
| Only U.S. state with a pennant-shaped flag | 42 |
| One of the rivers of Three Rivers Stadium | 41 |
| One of the rivers near Three Rivers Stadium | 43 |
| One of Cairo's rivers | 25 |
| Oberlin's state | 19 |
| Oberlin's home | 18 |
| Oberlin College's state | 27 |
| Noted bellwether | 16 |
| Not-so-lazy river | 17 |
| New addition of 1803 | 20 |
| Neil Young-penned song about midwest university | 47 |
| Neil Young song about Kent State | 32 |
| Neighbor of West Virginia | 25 |
| Neighbor of Indiana | 19 |
| Mississippi River's largest tributary | 41 |
| Miss. River tributary | 21 |
| Midwestern swing state | 22 |
| Midwest swing state | 19 |
| Miami University state | 22 |
| Miami University site | 21 |
| Miami University setting | 24 |
| Miami University location | 25 |
| Miami River's outlet | 24 |
| Miami River locale | 18 |
| Miami of _____ | 14 |
| Miami County's state | 24 |
| McKinley's home state | 25 |
| Locale for Dublin, Canton, Lima, and Medina | 43 |
| Locale for Columbus | 19 |
| Larry Flynt's home state | 28 |
| Land of Buckeyes | 16 |
| Lake Erie's neighbor | 24 |
| Lake Erie neighbor | 18 |
| Kentucky abutter | 16 |
| Kent State's home | 21 |
| Kent State tragedy song | 23 |
| Jim Backus's home state | 27 |
| Its three largest cities start with C | 37 |
| Its three largest cities all start with C | 41 |
| Its state quarter features an astronaut | 39 |
| Its state quarter bears an image of an astronaut | 48 |
| Its state bird is the cardinal | 30 |
| Its postal abbreviation is an exclamation | 41 |
| Its license plates say "Birthplace of Aviation" | 57 |
| Its flag has 17 stars and is nonrectangular | 43 |
| Its first capital was Chillicothe, 1803-10 | 42 |
| Its commemorative quarter depicts an astronaut | 46 |
| It was part of the Northwest Territory | 38 |
| It was once part of the Northwest Territory | 43 |
| It starts in Pittsburgh | 23 |
| It has a five-sided flag | 24 |
| Iroquoian for "Beautiful River" | 41 |
| Indiana/Kentucky border river | 29 |
| Indiana's smallest county or the river it touches | 53 |
| I-90 runs through it | 20 |
| Home to Cantonians | 18 |
| Home to Athens | 14 |