| Initiator of a probe, maybe | 27 |
| Initials at Cape Canaveral | 26 |
| I Dream of Jeannie backdrop | 30 |
| Hubble Telescope participant | 28 |
| HQ for Skylab men | 17 |
| Houston-based Govt. agency | 26 |
| Houston-based agcy. | 19 |
| Houston shuttle letters | 23 |
| High-flying letters | 19 |
| High-flier's org.? | 22 |
| Grp. that's out of this world? | 34 |
| Grp. that sends things up | 25 |
| Grp. running the Kepler, Curiosity, Cassini and Hubble missions | 63 |
| Grp. organizing booster shots | 29 |
| Grp. famous for its send-ups? | 29 |
| Grp. behind Magellan | 20 |
| Gp. with sky-high ambitions | 27 |
| Gp. that gave Tang sales a boost | 32 |
| Gp. that gave Glenn a lift | 26 |
| Govt. agcy. with an Image of the Day webpage | 44 |
| Government agency "launched" in 1958 | 46 |
| Glenn's employer, once | 26 |
| Gemini org. | 11 |
| Galileo's patron? | 21 |
| Galileo's gp. | 17 |
| Galileo org. | 12 |
| Galileo launcher: Abbr. | 23 |
| G-suit acronym | 14 |
| Friendship org. of 1962 | 23 |
| Frequent launcher | 17 |
| Far-out travel agency? | 22 |
| Exploratory org. | 16 |
| Endeavour sender | 16 |
| Endeavour initials | 18 |
| Employer of many scientists | 27 |
| Employee of many scientists | 27 |
| Dr. Jemison's former employer | 33 |
| Discovery's agcy. | 21 |
| Discovery launchers | 19 |
| Discovery gp. | 13 |
| Discovery agcy. | 15 |
| Curiosity producer | 18 |
| Cong. established it in 1958 | 28 |
| Columbia creator | 16 |
| Challenger's org. | 21 |
| Challenger's letters | 24 |
| Carpenter's employer, once | 30 |
| Cape Canaveral initials | 23 |
| Cape Canaveral grp. | 19 |
| Canaveral agency | 16 |
| Canadarm user, abbr. | 20 |
| Booster grp.? | 13 |
| Big rocket launcher | 19 |
| Big inits. in Houston | 21 |
| Atlas acronym | 13 |
| Atlantis' org. | 18 |
| Astronauts' HQ | 18 |
| Astronauts' agency | 22 |
| Astronaut's letters | 23 |
| Astronaut's employer, for short | 35 |
| Astronaut's agcy. | 21 |
| Astronaut's acronym | 23 |
| Astronaut agcy. | 15 |
| Apollo's sponsor | 20 |
| Apollo's org. | 17 |
| Apollo's launcher | 21 |
| Apollo program org. | 19 |
| Apollo launcher | 15 |
| Apollo grp. | 11 |
| Apollo 13 gp. | 13 |
| Ames Research Center org. | 25 |
| Aldrin's grp. | 17 |
| Aldrin's former employer | 28 |
| Air and Space Museum donor | 26 |
| Agency of long trips, for short | 31 |
| Agency established by DDE | 25 |
| Agcy. with far-out ideas | 24 |
| Agcy. that shoots for the stars | 31 |
| Agcy. that gave Ride a ride | 27 |
| Acronym on a shuttle | 20 |
| Acgy. above it all? | 19 |
| Abbr. on a U.S. rocket | 22 |
| Abbr. at Houston | 16 |
| 2011 launcher of Curiosity | 26 |
| "The Right Stuff" subj. | 33 |
| "The Right Stuff" group | 33 |
| "The Eagle has landed" recipient | 42 |
| "Space Cowboys" org. | 30 |
| "Space Cowboys" gp. | 29 |
| "Out to launch" org. | 30 |
| "New Horizons" sponsor | 32 |
| "Magnificent Desolation" org. | 39 |
| "Magellan" launcher | 29 |
| "Endeavour" group | 27 |
| "Discovery" org. | 26 |
| "Discovery" grp. | 26 |
| "Curiosity" launcher | 30 |
| "Columbia" org. | 25 |
| "Atlantis" launcher | 29 |
| "Apollo 13" org. | 26 |