| Statement of frustration | 24 |
| "Like I haven't heard that before" | 48 |
| "It doesn't matter" | 33 |
| Resigned response often accompanied by eye-rolling | 50 |
| "I'm so through with this discussion!" | 52 |
| "As if I care anyway" | 31 |
| "Anything you say" | 28 |
| "___ is, is right": Pope | 34 |
| 'It doesn't matter' | 31 |
| Motivated entrepreneur's motto | 34 |
| At any price | 12 |
| Best thing to try | 17 |
| Dismissive words to a wistful person? | 37 |
| 'Any audible breath will do'? | 37 |
| Chatroom "who cares?" | 31 |
| "These mortals," a la Shakespeare | 43 |
| “How come?” | 19 |
| "Why should I?" | 25 |
| "Why on earth would you do that?" | 43 |
| 'Why?' | 14 |
| "Can you explain this?" | 33 |
| Words said in disbelief | 23 |
| Query from the impatient | 24 |
| Phrase of protest | 17 |
| "Something's not right here ..." | 46 |
| Start of a proverb about consequences ... and a hint to this puzzle's theme | 79 |
| Long-story starter, perhaps | 27 |
| Question from Steven Wright, part 1 | 35 |
| "And now?" | 20 |
| "And afterward?" | 26 |
| "Why me?" | 19 |
| Other similar things | 20 |
| Catch-all words | 15 |
| Alternative to 'et cetera' | 34 |
| Question for Knotts when he's holding a package? | 52 |
| Question from the horrified | 27 |
| Quip to think about (Part 2) | 28 |
| "___ Like About You" | 30 |
| "--- Like About You" | 30 |
| "___ Did for Love," 1975 song | 39 |
| 1975 song from "A Chorus Line" | 40 |
| The therapist ... | 17 |
| Speculative question | 20 |
| Writer's plot-progression query | 35 |
| Start of an inventor's thought | 34 |
| "Just suppose ..." | 28 |
| Start of a hypothetical question | 32 |
| Start of a conjecture | 21 |
| Speculator's question | 25 |
| Speculation starter | 19 |
| Hypothetical first words | 24 |
| "Let's suppose..." | 32 |
| "Let's say ..." | 29 |
| "Let's pretend that ..." | 38 |
| "Consider this scenario ..." | 38 |
| Defiant question sometimes followed by "Would you still..." | 69 |
| Hypothetical questions | 22 |
| Start of a perplexed person's question | 42 |
| Start of a befuddled question from Chester to Mr. Dillon, perhaps | 65 |
| Goodness me! | 12 |
| Verse: Part V | 13 |
| "Ament ___!" | 22 |
| Response to an answer | 21 |
| Classic question answered six times in this puzzle | 50 |
| A question of aesthetics | 24 |
| A. Egg and matzo meal B. Tomatoes and cheese C. Corn or barley D. Chickpeas or beans | 84 |
| ... Boo or yoo follower | 23 |
| "Yes?" | 16 |
| Terse response when interrupted | 31 |
| Terse response to an interruption | 33 |
| Response to an interruption | 27 |
| Hit song of 1959 or 1993 | 24 |
| 1993 dance hit, and a question answered seven times in this puzzle | 66 |
| "Will you please hurry?" | 34 |
| "Can I help you?" | 27 |
| Physicist's query? | 22 |
| Statement of concern | 20 |
| Question of concern ... or another title for this puzzle | 56 |
| "Something wrong?" | 28 |
| Start of a diner's question to a B'way waiter | 53 |
| Finder's query | 18 |
| ... Massachusetts birthplace of the 19th-century feminist Elizabeth Packard | 75 |
| ... Oldtime radio station in a 1990's AMC series | 52 |
| ... English river, site of the ruins of Tintern Abbey | 53 |
| Cop's question to accident victim | 37 |
| End of conjecture | 17 |
| Words to a latecomer | 20 |
| Song popularized by Ethyl Merman? | 33 |
| "___ it be?" | 22 |
| "___ it be, pal?" | 27 |
| "__ it be?" (drink request) | 37 |
| Irving Berlin standard that begins "Gone is the romance that was so divine" | 85 |
| Berlin tune heard in "The Great Gatsby" | 49 |
| 1924 Irving Berlin tune | 23 |
| Question from the bar | 21 |
| Diner server's question | 27 |
| Bartender's query | 21 |
| Foreigner "I Want to Know ___" | 40 |
| Big Apple with no worms | 23 |
| Question asked by one watching the clock? | 41 |