| World's largest particle physics lab | 40 |
| The world's largest particle physics lab | 44 |
| Research org. in Geneva | 23 |
| Noted European lab | 18 |
| Huge particle physics lab in Europe | 35 |
| Geneva research ctr. | 20 |
| Enter upon an inheritance: Roman law | 36 |
| Decide: Rom. law | 16 |
| Decide, in Roman law | 20 |
| "Angels & Demons" antimatter org. | 47 |
| Apollo 10 crewman | 17 |
| Eugene and Buzz who took steps | 30 |
| Rick the catcher | 16 |
| Catcher Rick | 12 |
| Game fishes | 11 |
| Tropical mackerels | 18 |
| Mackerels' relatives | 24 |
| Large mackerel-like fish | 24 |
| Cavalla and pintado | 19 |
| Secreted: Sp. | 13 |
| Spanish hill | 12 |
| Juan's hill | 15 |
| Hill, in Honduras | 17 |
| ___ Gordo, county in Iowa | 25 |
| Richard Price novel | 19 |
| Reacts fearfully | 16 |
| Foolproof | 9 |
| Sure | 4 |
| Quite sure | 10 |
| Like death and taxes | 20 |
| Indubitable | 11 |
| Incontrovertible | 16 |
| These may be deducted | 21 |
| Of course | 9 |
| Arctic Monkeys' love affair (with "A")? | 53 |
| Sure things; specific Father's Day gifts? | 45 |
| Of course: L. | 13 |
| In truth, old-style | 19 |
| Fixed-term investments | 22 |
| Like some important letters | 27 |
| Like some accountants | 21 |
| Notarize | 8 |
| Freedom from doubt | 18 |
| Crayola shade of blue since 1990 | 32 |
| Sort of blue | 12 |
| End of a blue movie? | 20 |
| Sky blues | 9 |
| Earwax | 6 |
| Horned: Suffix | 14 |
| White lead | 10 |
| "Don Quixote" author | 30 |
| Quixote's creator | 21 |
| Creator of Don Quixote | 22 |
| Asker of the question | 21 |
| Deer: Prefix | 12 |
| Deerlike | 8 |
| Uterus part | 11 |
| Neck, anatomically | 18 |
| Area for an Ob/Gyn | 18 |
| Stop!: Sp. | 10 |
| West Indian poet | 16 |
| 5-time Gold Glove centerfielder for the Astros | 46 |
| Lucrezia Borgia's brother | 29 |
| One of the Borgias | 18 |
| Singer Siepi | 12 |
| Basso Siepi | 11 |
| Brother of Lucrezia Borgia | 26 |
| Siepi of opera | 14 |
| Lucrezia's brother | 22 |
| Italian writer Pavese | 21 |
| Famous Borgia | 13 |
| Cardinal Borgia | 15 |
| Borgia written about by Machiavelli | 35 |
| Borgia profiled in "The Prince" | 41 |
| Borgia or Siepi | 15 |
| Baby delivery method | 20 |
| It may bring out the kid in you | 31 |
| Plotter pursued by Scarpia | 26 |
| Where obstetricians meet? | 25 |
| Worshipers of Roman emperors? | 29 |
| Symphony in D minor composer | 28 |
| _____ section | 13 |
| Viola's alter ego in "Twelfth Night" | 50 |
| Olivia's love in "Twelfth Night" | 46 |
| Swiss "king of hoteliers" | 35 |
| Romero et al. | 13 |
| French Oscars | 13 |
| City east-northeast of Florence | 31 |
| British tax | 11 |
| Luck, in Ireland | 16 |
| Irish luck | 10 |
| Tax, in Britain | 15 |
| Pool start | 10 |
| Pool opening? | 13 |
| Word with pool or pit | 21 |
| The luck of the Irish? | 22 |
| Luck, in Limerick | 17 |
| Luck of the Irish | 17 |
| Word with "pool" or "pit" | 45 |
| Word before pit or pool | 23 |