| Sister of Mike in "For Better or for Worse" | 53 |
| Sister of Lucy, Edmund and Peter in the Narnia books | 52 |
| Sister of Albus Dumbledore, in the Harry Potter books | 53 |
| Sister of actor Emilio and semi-regular on "The West Wing" | 68 |
| Sis of Bob and Anna in "Mom and Dad Are Palindromes" | 62 |
| Sirtis's role in "Star Trek: The Next Generation" | 63 |
| Sir William ___ (one of Johns Hopkins Hospital's founders) | 62 |
| Sir William ___ (big name at Johns Hopkins Hospital) | 52 |
| Sir William ___ (A founder of Johns Hopkins Hospital) | 53 |
| Sir Topham ___ ("Thomas the Tank Engine" manager) | 59 |
| Sir Topham ___ ("Thomas the Tank Engine" boss) | 56 |
| Sir Edward who composed "Pomp and Circumstance" | 57 |
| Sir Charles's colleague on TV's "Inside the NBA" | 66 |
| Sioux chief (and what can be found in the circled squares?) | 59 |
| Singsongy "This is an uncomfortable moment" | 53 |
| Single-season record holder for most HRs by a shortstop | 55 |
| Single piece of potato used to excite a team's fanbase? | 59 |
| Single name that Denver Nuggets player Maybyner Hilario goes by | 63 |
| Single from the Smiths' "This Charming Man" | 57 |
| Single for the Rolling Stones in 1971 and D'Angelo in 1995 | 62 |
| Single for Kanye West in 2007 and Kelly Clarkson in 2011 | 56 |
| Single for Julie London in 1955 and Justin Timberlake in 2002 | 61 |
| Single for Chad Kroeger of Nickelback or Mariah Carey | 53 |
| Single for Black Sabbath in 1970 and Kanye West in 2009 | 55 |
| Singing sisters on "The Lawrence Welk Show" | 53 |
| Singing candelabra in "Beauty and the Beast" | 54 |
| Singers of the anthem "Nashid as-Salaam as-Sultani" | 61 |
| Singers of "Voulez-Vous" and "Waterloo" | 59 |
| Singer/songwriter Michael in "Boogie Nights" | 54 |
| Singer/pianist with the 2002 hit "A Sorta Fairytale" | 62 |
| Singer/guitarist born Maria Rosario Pilar Martinez Molina Baeza | 63 |
| Singer/dancer/actress once called the "Queen of Las Vegas" | 68 |
| Singer/actress with an Oscar, two Grammys and a Golden Globe | 60 |
| Singer/actress with a simultaneous #1 album and #1 film, familiarly | 67 |
| Singer/actress who made her Broadway debut in "Hair" (1968) | 69 |
| Singer/actress Karen of Broadway's "Nine" | 55 |
| Singer/actor who wrote "Here I Stand," 1958 | 53 |
| Singer with Top 10 hits in the 1960s, '70s, '80s and '90s | 69 |
| Singer with the triple-platinum album "The Memory of Trees" | 69 |
| Singer with the platinum album "Pink Friday" | 54 |
| Singer with the platinum 1992 album "The Celts" | 57 |
| Singer with the New Wave classic "Kids in America" | 60 |
| Singer with the hit country album "Backwoods Barbie" | 62 |
| Singer with the hit albums "19" and "21" | 60 |
| Singer with the hit album "The Hungry Years" | 54 |
| Singer with the hit album "Diamonds & Rust" | 57 |
| Singer with the hit "Angel of the Morning" | 52 |
| Singer with the first recording to sell a million copies | 56 |
| Singer with the double-platinum album "The Memory of Trees" | 69 |
| Singer with the double-platinum album "Measure of a Man" | 66 |
| Singer with the compilation "A Box of Dreams" | 55 |
| Singer with the children's album "Camp Lisa" | 58 |
| Singer with the albums "19" and "21" | 56 |
| Singer with the album "Mind, Body & Soul" | 55 |
| Singer with the album "Live at the Polynesian Palace" | 63 |
| Singer with the album "It's Alright (I See Rainbows)" | 67 |
| Singer with the album "I Ain't Movin'" | 56 |
| Singer with the album "Hawaiian Favorites" | 52 |
| Singer with the album "Gypsys, Tramps & Thieves" | 62 |
| Singer with the album "Classic Songs, My Way" | 55 |
| Singer with the album "Approximately Infinite Universe" | 65 |
| Singer with the 7x platinum single "Rolling in the Deep" | 66 |
| Singer with the 5x platinum album "Nick of Time," 1989 | 64 |
| Singer with the 4x platinum album "Watermark" | 55 |
| Singer with the 2014 top 10 hit "Boom Clap" | 53 |
| Singer with the 2008 gold record "And Winter Came ..." | 64 |
| Singer with the 1999 #1 hit "If You Had My Love" | 58 |
| Singer with the 1996 triple-platinum album "Tidal" | 60 |
| Singer with the 1996 #1 hit "You're Makin' Me High" | 69 |
| Singer with the 1995 album "Velvet and Brass" | 55 |
| Singer with the 1994 hit "Bump n' Grind" | 54 |
| Singer with the 1994 #1 hit "Bump N' Grind" | 57 |
| Singer with the 1994 #1 alternative rock hit "God" | 60 |
| Singer with the 1993 multi-platinum album "Music Box" | 63 |
| Singer with the 1992 album "Joshua Judges Ruth" | 57 |
| Singer with the 1990 #1 album "To the Extreme" | 56 |
| Singer with the 1988 Top Ten Hit "Walk on Water" | 58 |
| Singer with the 1988 #1 country hit "I'm Gonna Get You" | 69 |
| Singer with the 1984 hit "Caribbean Queen" | 52 |
| Singer with the 1983 #2 hit "Electric Avenue" | 55 |
| Singer with the 1980 #1 album "Against the Wind" | 58 |
| Singer with the 1975 #1 hit "Lady Marmalade" | 54 |
| Singer with the 1974 #1 hit "Rock Me Gently" | 54 |
| Singer with the 1966 hit "I'm So Lonesome I Could Cry" | 68 |
| Singer with the 1963 hit "If I Had a Hammer" | 54 |
| Singer with the 1960 #1 album "G.I. Blues" | 52 |
| Singer with the 1954 #1 hit "This Ole House" | 54 |
| Singer with the 1941 hit "San Antonio Rose" | 53 |
| Singer with the #1 R&B hit "I Feel for You" | 57 |
| Singer with the #1 hit "Don't Forbid Me" | 54 |
| Singer with the #1 country hit "Hello Darlin'" | 60 |
| Singer with the #1 country album "80's Ladies" | 60 |
| Singer with the #1 album "Between the Lines" | 54 |
| Singer with stars on Hollywood's and Canada's Walks of Fame | 67 |
| Singer with four recent best-selling albums of pop standards | 60 |
| Singer with an Oscar-nominated song from "Robin Hood" | 63 |
| Singer with 11 #1 country hits prepares letters for mailing? | 60 |
| Singer whose name sounds like an Olympic speed skater | 53 |
| Singer whose name is an anagram of "enlarge" | 54 |
| Singer whose band just appeared unannounced in your iTunes collection | 69 |