| Site of "Moses' cave" | 35 |
| Site of "Lost Horizon" | 32 |
| Site of "Last Supper" mural | 37 |
| Site of "interstates" H1, H2 and H3 | 45 |
| Site of "a poem in marble" | 36 |
| Site of 'bombs bursting' | 32 |
| Site in the ''Aeneid'' | 38 |
| Site in a poor-protection simile | 32 |
| Site in "Julius Caesar" | 33 |
| Site fortified by Herod the Great | 33 |
| Site for some monitoring bracelets | 34 |
| Site for serious treatment, briefly | 35 |
| Site for selling handmade crafts | 32 |
| Site for nursery rhyme blackbirds | 33 |
| Site for many a French connection | 33 |
| Site for hosting winter pajamas pictures? | 41 |
| Site for eating and entertainment | 33 |
| Site for Christmas lights, often | 32 |
| Site for checkers games, back in the day | 40 |
| Site for a state slogan, perhaps | 32 |
| Site for a pocket billiards tournament? | 39 |
| Site for a monitoring bracelet, maybe | 37 |
| Site for a Jesus painting, perhaps | 34 |
| Site for a child's clubhouse, perhaps | 41 |
| Site associated with this puzzle's theme | 44 |
| Sitcom's Schneider, for instance | 36 |
| Sitcom with the theme "Angela" | 40 |
| Sitcom with the character Alex Rieger | 37 |
| Sitcom with a show called "Tool Time" | 47 |
| Sitcom with a famous Turkey Drop episode | 40 |
| Sitcom with a coming-out episode | 32 |
| Sitcom with a 2,000-year-old character | 38 |
| Sitcom wife with a grating voice | 32 |
| Sitcom whose theme song was sung by its star | 44 |
| Sitcom where Slappy White played Melvin | 39 |
| Sitcom title role for Brandy Norwood | 36 |
| Sitcom title character with the last name Hart | 46 |
| Sitcom title character in a nuns' residence? | 48 |
| Sitcom that starred Charles S. Dutton | 37 |
| Sitcom that received 17 Emmy nominations in 2011 | 48 |
| Sitcom that premiered in '88 | 32 |
| Sitcom that launched Joey Lawrence's career | 47 |
| Sitcom that featured the Soup Nazi | 34 |
| Sitcom that featured Andy Kaufman | 33 |
| Sitcom teacher at James Buchanan High | 37 |
| Sitcom starring a country singer | 32 |
| Sitcom spender of brandels and grebbels | 39 |
| Sitcom set at the Sunshine Cab Company | 38 |
| Sitcom psychiatrist Frasier, to his patients | 44 |
| Sitcom pal of Barbarino and Horshack | 36 |
| Sitcom on which everyone overacts? | 34 |
| Sitcom oldie, 'Kate & --' | 37 |
| Sitcom named for its country star | 33 |
| Sitcom mother of Serge and Saffron | 34 |
| Sitcom in which Sherman Hemsley played a deacon | 47 |
| Sitcom hubby played by two Dicks | 32 |
| Sitcom featuring the Douglas family | 35 |
| Sitcom featuring Paul and Jamie Buchman | 39 |
| Sitcom featured in "Man in the Moon" | 46 |
| Sitcom E.T. voiced by Paul Fusco | 32 |
| Sitcom dry cleaning business owner | 34 |
| Sitcom creature from outer space | 32 |
| Sitcom created by Sidney Sheldon | 32 |
| Sitcom costar of Betty and Estelle | 34 |
| Sitcom cook who said "Stow it!" | 41 |
| Sitcom co-star of Betty and Estelle | 35 |
| Sitcom characters Borland and Bundy | 35 |
| Sitcom character with "many loves" | 44 |
| Sitcom character who lived with the Tanners | 43 |
| Sitcom character who got married on 10/28/74 | 44 |
| Sitcom character in apartment 5B | 32 |
| Sitcom at Dunder Mifflin, with "The" | 46 |
| Sitcom Arthur better known by his nickname | 42 |
| Sitcom actor who regularly cross-dressed | 40 |
| Sitcom acted mostly on barstools | 32 |
| Sitcom about Jerry, George, Elaine and Kramer | 45 |
| Sitcom about an endearing dimwit? | 33 |
| Sitcom about a wacky deck crew leader? | 38 |
| Sitcom about a team of aromatherapists? | 39 |
| Sitcom about a computer language? | 33 |
| Sit-down strikers of 1937: Abbr. | 32 |
| Sit ungracefully, with "down" | 39 |
| Sit ungracefully (with "down") | 40 |
| Sit in on classes, but not for credit | 37 |
| Sit down with an old favorite book | 34 |
| Sit clumsily (with "down") | 36 |
| Sisyphus' punishment, in myth? | 34 |
| Sisyphus' exasperated query? | 32 |
| Sistine Chapel site, with "the" | 41 |
| Sistine Chapel ceiling depiction | 32 |
| Sisters of Charity founder and family | 37 |
| Sisterhood name in a Rebecca Wells novel | 40 |
| Sister _____ of "Guys and Dolls" | 42 |
| Sister ___, title character of a 1970 film | 42 |
| Sister ___ of "Guys and Dolls" | 40 |
| Sister ___ ("We Are Family" singers) | 46 |
| Sister who's won the U.S. Open three times | 46 |
| Sister Sledge: "___ Family" | 37 |
| Sister Sledge's "We _____ Family" | 47 |
| Sister Sledge's "We ___ Family" | 45 |