| Descriptor for many a supermodel | 32 |
| Descriptor for many hip-hop musicians | 37 |
| Descriptor for this puzzle's theme | 38 |
| Descriptor of a sea snake's tail | 36 |
| Descriptor of Scarlett O'Hara | 33 |
| Desdemona's faithful servant | 32 |
| Desdemona's handkerchief, e.g. | 34 |
| Desdemona's husband and murderer | 36 |
| Desert ''monster'' | 34 |
| Desert along the Sinai Peninsula | 32 |
| Desert beast with three lids on each eye | 40 |
| Desert bordering the Sinai Peninsula | 36 |
| Desert bounded by the Altai Mountains | 37 |
| Desert plant for which a U2 album is named | 42 |
| Desert plant named for a Biblical spy | 37 |
| Desert plants with sword-shaped leaves | 38 |
| Desert plants with white flowers | 32 |
| Desert region in the south of Israel | 36 |
| Desert south of the Atlas Mountains | 35 |
| Desert that borders the Altai Mountains | 39 |
| Desert that covers most of North Africa | 39 |
| Desert that occasionally gets snow | 34 |
| Desert that's a significant part of Mongolia | 48 |
| Desert that's second to the Sahara in size | 46 |
| Desert when another is in trouble | 33 |
| Desert whose name means "semidesert" | 46 |
| Desert ___ (1991 military operation) | 36 |
| Deserted spot, especially for one who is lost | 45 |
| Desertlike region of the Arabian Peninsula | 42 |
| Deserved the Hall of Fame ceremony | 34 |
| Deserving a lower insurance premium | 35 |
| Deserving of a lower insurance premium | 38 |
| Desi Arnaz's better half, at one time | 41 |
| Design division of the New School | 33 |
| Design feature of many a viaduct | 32 |
| Design for a mountain cabin, often | 34 |
| Design on Charlie Brown's shirt | 35 |
| Design pattern on some Irish crosses | 36 |
| Design style popular in the '20s and '30s | 49 |
| Designate, as if by divine intervention | 39 |
| Designated area for Southern dialogue? | 38 |
| Designated driver's drink, perhaps | 38 |
| Designating a fine, white marble | 32 |
| Designating private or secret sessions | 38 |
| Designating the style of an earlier time | 40 |
| Designation at an Arabic meat market | 36 |
| Designation ditched after smoking bans | 38 |
| Designation for a sequel to a sequel | 36 |
| Designation for driver's licenses | 37 |
| Designation for private global grps. since 1945 | 47 |
| Designation for some batteries and minor-leaguers | 49 |
| Designation for some transgendered people | 41 |
| Designation of Sen. Angus King of Maine | 39 |
| Designation of some meat markets | 32 |
| Designation on a driver's license, perhaps | 46 |
| Designation on a U.S. savings bond | 34 |
| Designations for secret papers of 1790's | 44 |
| Designed for shooting gross globs? | 34 |
| Designed for, with "towards" | 38 |
| Designed to conform with existing modes | 39 |
| Designed to defeat a Panzer, say | 32 |
| Designed to minimize wind resistance | 36 |
| Designed to prevent intrusion, in a way | 39 |
| Designed to reduce wind resistance | 34 |
| Designed to teach a hard lesson, maybe | 38 |
| Designed with lots of glass and metal, for short | 48 |
| Designed with standard-sized units | 34 |
| Designer born in Guangzhou, China | 33 |
| Designer Christian doing a pirouette? | 37 |
| Designer Coco, while "hanging ten"? | 45 |
| Designer Edith . . . or movie mogul | 35 |
| Designer for Lillian Gish and Anna Pavlova | 42 |
| Designer Gabbana of Dolce & Gabbana | 39 |
| Designer in J.F.K.'s White House | 36 |
| Designer known for her wedding gowns | 36 |
| Designer known for his "American look" | 48 |
| Designer McCartney, daughter of Paul and Linda | 46 |
| Designer monogram under the Gucci label | 39 |
| Designer of a famous French tower | 33 |
| Designer of D.C.'s L'Enfant Plaza | 41 |
| Designer of Dallas's Patriot Tower | 38 |
| Designer of DjoserÂ’s tomb in Saqqara | 40 |
| Designer of Dulles Airport's main terminal | 46 |
| Designer of Genoa's National Opera House | 44 |
| Designer of Harvard's Kennedy Library | 41 |
| Designer of Hong Kong's Bank of China Tower | 47 |
| Designer of Kennedy Library at Harvard | 38 |
| Designer of London's St. Paul's Cathedral | 49 |
| Designer of Massachusetts' state symbol | 43 |
| Designer of MIT's Building 54 | 33 |
| Designer of New York's Javits Center | 40 |
| Designer of Niagara power system | 32 |
| Designer of Saint Paul's Cathedral | 38 |
| Designer of St. Paul's Cathedral | 36 |
| Designer of St. Paul's Cathedral in London | 46 |
| Designer of the Chupa Chups lollipop logo | 41 |
| Designer of the first working nuclear reactor | 45 |
| Designer of the Mae West Lips Sofa | 34 |
| Designer of the Prado tapestries | 32 |
| Designer of the Republican elephant | 35 |