| Der ___ (German "father") | 35 |
| Der ___ (Konrad Adenauer's nickname) | 40 |
| Der ___ Fritz (Friedrich the Great) | 35 |
| Der ___ Herr (the old man): Ger. | 32 |
| Derby and Preakness winner: 1981 | 32 |
| Derby blasts, and key to this puzzle's theme | 48 |
| Derby winner, 1956, or thread holders | 37 |
| Derbyshire home of the dukes of Devonshire | 42 |
| Derek Jeter solves puzzles using . . . | 38 |
| Derek of "Gosford Park" | 33 |
| Derek of "I, Claudius" | 32 |
| Derek Trucks' rocker wife Susan | 35 |
| Derek's infield neighbor, familiarly | 40 |
| Derek, B.'s co-star got hitched | 35 |
| Derisive (or James Brown-ish) laughs | 36 |
| Derivative of "servus" (slave) | 40 |
| Derivatives of it are used in sunscreen | 39 |
| Derived great pleasure from chastising? | 39 |
| Dermatological diagnosis, perhaps | 33 |
| Dermatological diagnosis, sometimes | 35 |
| Dermatologist's diagnosis, perhaps | 38 |
| Dermatologist's favorite film (2004) | 40 |
| Dermatologist's pronouncement? | 34 |
| Dermatologist's removal, perhaps | 36 |
| Dern in ''Jurassic Park'' | 41 |
| Dern of "Jurassic Park" | 33 |
| Dernier ___ (the latest fashion) | 32 |
| Derogatory term popularized by George H. W. Bush | 48 |
| Descartes found this truth to be self-evident | 45 |
| Descartes who thought "I think ..." | 45 |
| Descartes who wrote "Cogito, ergo sum" | 48 |
| Descartes' "therefore" | 36 |
| Descartes's "sum," translated | 43 |
| Descartes's "therefore" | 37 |
| Descendant of Aaron, in the Bible | 33 |
| Descendant of an ancient Egyptian | 33 |
| Descendant of an Edison invention | 33 |
| Descendant of Canaan (anagram of A KITER) | 41 |
| Descendant of Fatima, to Shiites | 32 |
| Descendant of Japanese immigrants | 33 |
| Descendant of Noah's eldest son | 35 |
| Descendant of Noah's second son | 35 |
| Descendants of ancient Mesopotamians | 36 |
| Descendants of Moses' brother | 33 |
| Descendants through a single strain | 35 |
| Descended from a saddle, perhaps | 32 |
| Descended from the same language | 32 |
| Descended on the mother's side | 34 |
| Descendents "Coffee ___" | 34 |
| Descent before the parachute opens | 34 |
| Descent, before the parachute opens | 35 |
| Deschanel of "(500) Days of Summer" | 45 |
| Deschanel of "New Girl" | 33 |
| Describes some soils and sloughs | 32 |
| Describing a branch of the service | 34 |
| Describing a certain type of wit | 32 |
| Describing a numismatist's treasure | 39 |
| Describing a paperback's dearer relative | 44 |
| Describing a route from N.A. to London | 38 |
| Describing an anchor clear of the bottom | 40 |
| Describing an illegal labor contract | 36 |
| Describing an Italian diva's pasta dish | 43 |
| Describing Assyrians and Phoenicians | 36 |
| Describing certain tasteless jokes | 34 |
| Describing characters like b, q and r | 37 |
| Describing Ford Maddox Ford's soldier | 41 |
| Describing random molecular motion | 34 |
| Describing some bitterns and flycatchers | 40 |
| Describing Superman's vision | 32 |
| Describing symphonies, sonatas, etc. | 36 |
| Describing the anatomy of a stove? | 34 |
| Describing the least subtle actors | 34 |
| Describing the proverbial two peas | 34 |
| Describing the quarters of some caretakers | 42 |
| Describing the right side of the map | 36 |
| Describing the world's numbers | 34 |
| Describing winds from the Orient | 32 |
| Description of a certain citrus fruit | 37 |
| Description of a good novel or script | 37 |
| Description of a great fighter, perhaps | 39 |
| Description of a sunset, perhaps | 32 |
| Description of an 18th-century writing desk? | 44 |
| Description of an oyster shell's shape | 42 |
| Description of extremely dry champagne | 38 |
| Description of items in a supermarket mailer? | 45 |
| Description of something that's very funny | 46 |
| Description of the office of the President | 42 |
| Description of the stock market (Part 1) | 40 |
| Description on many eBay listings | 33 |
| Description that's bee-fitting? | 35 |
| Descriptions on a commercial box | 32 |
| Descriptive of 10 answers in this puzzle | 40 |
| Descriptive of a lemony dessert? | 32 |
| Descriptive of an intimate dinner | 33 |
| Descriptive of DeMille's work | 33 |
| Descriptive of how some greet others? | 37 |
| Descriptive of this puzzle's grid | 37 |
| Descriptive of Yo-Yo Ma's music? | 36 |
| Descriptive words for Ben Jonson | 32 |
| Descriptor for a domineering person | 35 |