| Most important point | 20 |
| Most important skill | 20 |
| Most important steps | 20 |
| Most important thing to do | 26 |
| Most important U.S. Open match | 30 |
| Most important, or noted film studio | 36 |
| Most importantly | 16 |
| Most imposing | 13 |
| Most imposingly fashionable | 27 |
| Most impoverished | 17 |
| Most impressive | 15 |
| Most impudent | 13 |
| Most impulsive | 14 |
| Most in need of a chimney sweep | 31 |
| Most in need of a doctor | 24 |
| Most in need of a dye job? | 26 |
| Most in need of a haircut | 25 |
| Most in need of a moisturizer | 29 |
| Most in need of a rubdown | 25 |
| Most in need of a shower, perhaps | 33 |
| Most in need of Beano, maybe | 28 |
| Most in need of breaking in | 27 |
| Most in need of calamine lotion | 31 |
| Most in need of Grecian Formula | 31 |
| Most in need of help | 20 |
| Most in need of insulation | 26 |
| Most in need of liniment | 24 |
| Most in need of magnification | 29 |
| Most in need of massage | 23 |
| Most in need of toning | 22 |
| Most in vogue, as fashion | 25 |
| Most in-style, say | 18 |
| Most inaccurate | 15 |
| Most inactive | 13 |
| Most inadequate | 15 |
| Most inane | 10 |
| Most inclined to dawdle | 23 |
| Most inclusive | 14 |
| Most indecent | 13 |
| Most independent | 16 |
| Most Indians | 12 |
| Most indigent | 13 |
| Most indiscreet | 15 |
| Most indisputable | 17 |
| Most indistinct | 15 |
| Most indolent | 13 |
| Most inebriated | 15 |
| Most inexperienced | 18 |
| Most inexpert | 13 |
| Most inexplicable | 17 |
| Most inferior | 13 |
| Most inferior in quality | 24 |
| Most inferior in station | 24 |
| Most inferior sausage? | 22 |
| Most inferior shoe bottoms? | 27 |
| Most infielders | 15 |
| Most informative, in a way | 26 |
| Most infrequent | 15 |
| Most ingenious | 14 |
| Most inhuman | 12 |
| Most innocent and unworldly | 27 |
| Most innovative | 15 |
| Most innuendo-laden | 19 |
| Most inscrutable | 16 |
| Most insensitive | 16 |
| Most insidious | 14 |
| Most insightful | 15 |
| Most insignficant | 17 |
| Most insignificant | 18 |
| Most insincere | 14 |
| Most insipid | 12 |
| Most insistent | 14 |
| Most insolent | 13 |
| Most insufficient | 17 |
| Most intelligent | 16 |
| Most intense | 12 |
| Most intense, as a gaze | 23 |
| Most interstates | 16 |
| Most intimate | 13 |
| Most intrepid | 13 |
| Most intrusive | 14 |
| Most IRA spenders | 17 |
| Most Iraqis | 11 |
| Most Iraqis, e.g. | 17 |
| Most irascible | 14 |
| Most irate | 10 |
| Most ironic | 11 |
| Most irritable | 14 |
| Most irritated | 14 |
| Most irritating | 15 |
| Most isolated | 13 |
| Most itsy-bitsy | 15 |
| Most jam-packed | 15 |
| Most Jordanians | 15 |
| Most joyful | 11 |
| Most jubilant | 13 |
| Most judicious | 14 |
| Most junior: Abbr. | 18 |
| Most junk mail | 14 |
| Most junk mail, essentially | 27 |