| Most draftable, once | 20 |
| Most drama critics | 18 |
| Most dreadful | 13 |
| Most dreaming occurs in the last one | 36 |
| Most dreary | 11 |
| Most drenched | 13 |
| Most dried-out, as bread | 24 |
| Most driver's ed students | 29 |
| Most driver-ed students | 23 |
| Most drunk | 10 |
| Most drunken | 12 |
| Most dry | 8 |
| Most dubious | 12 |
| Most eager | 10 |
| Most eager to go | 16 |
| Most ear-piercing | 17 |
| Most earthlings | 15 |
| Most earthy | 11 |
| Most easily heard | 17 |
| Most easily sunburned, maybe | 28 |
| Most easy to see | 16 |
| Most eccentric | 14 |
| Most economical | 15 |
| Most economical in business | 27 |
| Most edgy | 9 |
| Most eerie | 10 |
| Most effective infield cover? | 29 |
| Most efficient | 14 |
| Most effortful | 14 |
| Most egregious | 14 |
| Most Egyptians | 14 |
| Most elaborate | 14 |
| Most elderly | 12 |
| Most elegant | 12 |
| Most elementary | 15 |
| Most elevated | 13 |
| Most eligible | 13 |
| Most eligible for military service | 34 |
| Most eligible for service | 25 |
| Most eligible for the draft | 27 |
| Most eligible to be drafted | 27 |
| Most eligible, in a way | 23 |
| Most eligible, once | 19 |
| Most eligible, to the SSS | 25 |
| Most elusive | 12 |
| Most emaciated | 14 |
| Most embarrassed | 16 |
| Most embarrassed, colorwise | 27 |
| Most enamored (of) | 18 |
| Most encompassing | 17 |
| Most enduring | 13 |
| Most energetic | 14 |
| Most enjoyable toy before noon? | 31 |
| Most enlightened | 16 |
| Most enthusiastic | 17 |
| Most envied at the beach perhaps | 33 |
| Most envied at the beach, perhaps | 33 |
| Most equable | 12 |
| Most equitable | 14 |
| Most erotic | 11 |
| Most erratic | 12 |
| Most essential | 14 |
| Most essential part | 19 |
| Most ethereal | 13 |
| Most evasive | 12 |
| Most evenhanded | 15 |
| Most evidently just back from a Miami vacation, say | 51 |
| Most evil | 9 |
| Most evolved mammal | 19 |
| Most exaggerated | 16 |
| Most exaggerated, as a tale | 27 |
| Most excellent | 14 |
| Most excellent, in modern slang | 31 |
| Most exceptional | 16 |
| Most exclusive | 14 |
| Most exorbitant | 15 |
| Most expansive | 14 |
| Most expensive | 14 |
| Most exposed | 12 |
| Most expressionless | 19 |
| Most exquisite | 14 |
| Most exsuccous | 14 |
| Most extended | 13 |
| Most extensive | 14 |
| Most extreme | 12 |
| Most extreme degree | 19 |
| Most extreme state | 18 |
| Most extreme suffix | 19 |
| Most facile | 11 |
| Most faint | 10 |
| Most fair | 9 |
| Most faithful | 13 |
| Most fake | 9 |
| Most familiar | 13 |
| Most famous director of the United States Marine Band | 53 |
| Most famous grandson of Josiah Wedgwood | 39 |
| Most famous guy on the Planet | 29 |
| Most famous Hogwarts pupil | 26 |
| Most famous Nova Scotian | 24 |
| Most famous resident of Warm Spr., Ga. | 38 |