| Mega-hit? | 9 |
| Mega-marathon? | 14 |
| Mega-quantity, low-quality computer apps | 40 |
| Mega-retailer based in Minneapolis | 34 |
| Mega-screen film format | 23 |
| Mega-selling singing family | 27 |
| Mega-selling vocalist | 21 |
| Megabucks | 9 |
| Megabucks amount, for short | 27 |
| Megabucks event? | 16 |
| Megacelebrity | 13 |
| Megachurch's setting, perhaps | 33 |
| Megacompany who hired a spokesdude named Steven | 47 |
| Megacomputer sci-fi film | 24 |
| Megacorporation | 15 |
| Megadeth "___ Le Monde" | 33 |
| Megadeth "___ Writings" | 33 |
| Megadeth song about fibber? | 27 |
| Megadeth's genre | 20 |
| Megadeth's music genre | 26 |
| Megadeth's Mustaine | 23 |
| Megadeth: "The Holy Wars ... The Punishment ___" | 58 |
| Megadeth: "___, So Good ... So What!" | 47 |
| Megadyne fractions | 18 |
| Megaera, Tisiphone, and Alecto, collectively | 44 |
| Megaflop | 8 |
| Megagametophyte containers | 26 |
| Megagram | 8 |
| Megahit | 7 |
| Megahit by Johnnie Ray | 22 |
| Megahit TV series | 17 |
| Megalithic monument | 19 |
| Megaliths site in the Pacific | 29 |
| Megalomania? | 12 |
| Megalomaniac's desire | 25 |
| Megalomaniac's problem | 26 |
| Megalomaniac, e.g. | 18 |
| Megalomaniacal captain | 22 |
| Megalomaniacal feature | 22 |
| Megalopolis with about 30 million people, for short | 51 |
| Megamistake | 11 |
| Megan of "Will & Grace" | 37 |
| Megan or Michael J. | 19 |
| Megan's "Will & Grace" role | 45 |
| Megaphone and soapbox, e.g.? | 28 |
| Megaphone for a ghost? | 22 |
| Megaphone-shaped | 16 |
| Megaplex count | 14 |
| Megaproportioned | 16 |
| Megaquantities | 14 |
| Megastar | 8 |
| Megastars | 9 |
| Megastore descriptor | 20 |
| Megaton material | 16 |
| Megaupload pursuers | 19 |
| Meghalaya's capital | 23 |
| Meghan Daum piece, e.g. | 23 |
| Megillah book | 13 |
| Megs aplenty | 12 |
| Megyn Kelly's channel | 25 |
| Meh | 3 |
| Mehitabel's chronicler | 26 |
| Mehitabel's companion | 25 |
| Mehitabel's creator | 23 |
| Mehitabel's crony | 21 |
| Mehitabel's friend et al. | 29 |
| Mehitabel's plaint | 22 |
| Mehitabel, e.g. | 15 |
| Mehitabel, for one | 18 |
| Mehmet ___, builder of Istanbul's Blue Mosque | 49 |
| Mehrabad Airport setting | 24 |
| Mehrabad International Airport site | 35 |
| Mehta and Ozawa | 15 |
| Mehta contemporary | 18 |
| Mehta leads one | 15 |
| Mehta or Ozawa | 14 |
| Mehta or Toscanini, e.g. | 24 |
| Mehta waves it | 14 |
| Mehta's gp., e.g. | 21 |
| Mehta's need | 16 |
| Mehta's rate | 16 |
| Mehta's successor at the New York Philharmonic | 50 |
| Mehta's tools | 17 |
| Mehta's wand | 16 |
| Mei Xiang and Tai Shan, e.g. | 28 |
| Mei Xiang or Tian Tian of the National Zoo | 42 |
| Mei-ling _____ , Mrs. Chiang Kai-shek | 39 |
| Meier and Dayan | 15 |
| Meier and Rabin | 15 |
| Meiji constitution drafter | 26 |
| Meiji prime minister | 20 |
| Meiji Shrine locale | 19 |
| Meiji statesman | 15 |
| Mein dish? | 10 |
| Mein ___ | 8 |
| Meineke stock item | 18 |
| Meiosis output | 14 |
| Meiosis product | 15 |
| Meir | 4 |
| Meir and Rabin, briefly | 23 |