| "Designate a Driver" org. | 35 |
| Parents who advocate cab rides, for short | 41 |
| Org. whose success is no accident? | 34 |
| Org. that advocates tough liquor laws | 37 |
| Org. that advocates none for the road | 37 |
| Org. fighting inebriated autoists | 33 |
| Org. concerned with blood-alcohol limits | 40 |
| Grp. advocating tough liquor laws | 33 |
| Grass-roots org. that fights alcohol abuse | 42 |
| Gp. with a key and a martini glass in its logo | 46 |
| Gp. that fights underage alcohol consumption | 44 |
| Gp. against inebriates at the wheel | 35 |
| "Designate a Driver" sponsor | 38 |
| Something to make in a downpour? | 32 |
| Surname followed by a year in video games | 41 |
| Name on many football video games | 33 |
| Memorable telestrator user in NFL broadcasts | 44 |
| “___ NFL” (video game series) | 37 |
| Rose of a Stephen King best seller | 34 |
| Climbing plant with a dye-yielding root | 39 |
| Radiohead "How I ___ My Millions" | 43 |
| Like an undercover cop whose cover is blown | 43 |
| Like a Marine's bed, usually | 32 |
| Identified, as an undercover cop | 32 |
| "We've got it ___!" | 33 |
| "These Boots Were ___ for Walking" | 44 |
| Tyler Perry's grandmother character | 39 |
| Seized an opportunity to gain advantage | 39 |
| Responded to opportunity's knock | 36 |
| "The sea is his, and he ___": Psalms | 46 |
| Had an average game on the green | 32 |
| Sinclair in "Coming To America" | 41 |
| Palmolive dishwashing liquid spokeswoman | 40 |
| Daughter in Inge's "Picnic" | 41 |
| "Alice in Wonderland" creature | 40 |
| Savage Garden "Truly ___ Deeply" | 42 |
| "Love Her ___" The Doors | 34 |
| Many an old horror film scientist, e.g. | 39 |
| Star-making title role for Mel Gibson | 37 |
| Hero of three George Miller movies | 34 |
| Film hero chasing a motorcycle gang | 35 |
| Film followed up by "The Road Warrior" | 48 |
| Emmy-winning AMC series set in the 1960s | 40 |
| Show set in NYC during the 1960s | 32 |
| AMC drama featuring Dick Whitman | 32 |
| "I understand __": Anthony Hopkins | 44 |
| Small amount of cash saved for an emergency | 43 |
| "O, that way __ lies": Lear | 37 |
| "Like a Prayer" singer | 32 |
| ''4 Minutes'' singer | 36 |
| Raphael's "Sistine ___" | 37 |
| "Papa Don't Preach" singer | 40 |
| "Open Your Heart" vocalist | 36 |
| "Express Yourself" singer | 35 |
| "Die Another Day" theme singer | 40 |
| "Crazy for You" singer | 32 |
| Fabric named for a city in India | 32 |
| Indian city now known as Chennai | 32 |
| Cotton fabric named for an Indian city | 38 |
| "The Treasure of the Sierra ___" | 42 |
| Mexican mountain system, Sierra ___ | 35 |
| She's married...with niños | 33 |
| She's married ... with niños | 39 |
| "Treasure of the Sierra __" | 37 |
| "Treasure of the Sierra ___" | 38 |
| 'The Treasure of the Sierra --' | 39 |
| Where the Spanish Parliament sits | 33 |
| Placido Domingo's birthplace | 32 |
| Renaissance musical compositions | 32 |
| "Sin City" actor Michael | 34 |
| Oscar-nominated actress for "Sideways" | 48 |
| "Sideways" Oscar nominee Virginia | 43 |
| "Sideways" actress Virginia | 37 |
| "Reservoir Dogs" actor Michael | 40 |
| Sketch show with Dollar Bill Montgomery | 39 |
| Show Michael McDonald left in 2008 | 34 |
| Long-running "S.N.L." rival | 37 |
| Fox sketch comedy show for Sasso and Spears | 43 |
| Fox series based on a humor magazine | 36 |
| Comedy show produced by Quincy Jones | 36 |
| "SNL" alternative on Fox since 1995 | 45 |
| "SNL" alternative from 1995 to 2009 | 45 |
| Cary's "She Done Him Wrong" costar | 48 |
| Cary's costar in "I'm No Angel" | 49 |
| West of "My Little Chickadee" | 39 |
| ___ West (inflatable life jacket) | 33 |
| West of "She Done Him Wrong" | 38 |
| West of "I'm No Angel" | 36 |
| West in "Night After Night" | 37 |
| Sallie ___ (student loan company) | 33 |
| First name among vivacious actresses | 36 |
| ___ West ("Diamond Lil" star) | 39 |
| West of ''My Little Chickadee'' | 47 |
| Tina Turner's real middle name | 34 |
| Fannie __ (federal mortgage agency) | 35 |
| Clarke of "Frankenstein" | 34 |
| Cary's "I'm No Angel" costar | 46 |
| Actress Busch of many Laurel and Hardy films | 44 |
| "She Done Him Wrong" actress West | 43 |
| ''Of Mice and Men'' wife | 40 |