| Largest tributary of the Missouri | 33 |
| Largest tributary of the Colorado | 33 |
| Largest tribal group in the U.S. | 32 |
| Largest terrestrial North American mammal | 41 |
| Largest Southern Hemisphere city | 32 |
| Largest South African ethnic group | 34 |
| Largest school in the Granite St. | 33 |
| Largest S.A. country, to inhabitants | 36 |
| Largest river of southern California | 36 |
| Largest professional employee org. in the U.S. | 46 |
| Largest privately owned Hawaiian island | 39 |
| Largest peninsula in the Western Hemisphere | 43 |
| Largest of the Tuscan Archipelago | 33 |
| Largest of the seven United Arab Emirates | 41 |
| Largest of the Galapagos Islands | 32 |
| Largest of the Dodecanese Islands | 33 |
| Largest of the British Virgin Islands | 37 |
| Largest of New York's Finger Lakes | 38 |
| Largest of CanadaÂ’s First Nations | 37 |
| Largest of British Virgin Islands | 33 |
| Largest number in a deck of cards | 33 |
| Largest moon in the solar system | 32 |
| Largest member of the dolphin family | 36 |
| Largest member of the deer family | 33 |
| Largest living fish (Rhincodon typus) | 37 |
| Largest lake in the Sierra Nevada | 33 |
| Largest island of French Polynesia | 34 |
| Largest island in the West Indies | 33 |
| Largest island in the United States | 35 |
| Largest island in the Tuscan Archipelago | 40 |
| Largest island in the Sulu Archipelago | 38 |
| Largest inland city in California | 33 |
| Largest Greek island after Crete | 32 |
| Largest freshwater lake in Israel | 33 |
| Largest employer in Newton, Iowa, until 2006 | 44 |
| Largest dwarf planet in the solar system | 40 |
| Largest division of geologic time | 33 |
| Largest country wholly in Europe | 32 |
| Largest country in the Caribbean | 32 |
| Largest country entirely in Europe | 34 |
| Largest container ship operator in the world | 44 |
| Largest college fraternity, familiarly | 38 |
| Largest college fraternity in the U.S., in brief | 48 |
| Largest city paper in the U.S.: Abbr. | 37 |
| Largest city on the island of Hawaii | 36 |
| Largest city on the Illinois River | 34 |
| Largest city on the Belgian coast | 33 |
| Largest city on Belgium's coast | 35 |
| Largest city north of the Arctic Circle | 39 |
| Largest city in the state of Guerrero | 37 |
| Largest city in the South Pacific | 33 |
| Largest city in the Maritime Provinces | 38 |
| Largest city in the Cornhusker State | 36 |
| Largest city in the Cornhusker St. | 34 |
| Largest city in the Baltic states | 33 |
| Largest city in Nordrhein-Westfalen | 35 |
| Largest city in California's wine country | 45 |
| Largest campus of Long Island Univ. | 35 |
| Largest asteroid in the solar system | 36 |
| Largest Arab country in the world | 33 |
| Largest and furthest of the dwarf planets | 41 |
| Largest active volcano in Europe | 32 |
| Largest "New Deal" agcy. | 34 |
| Largess from the highway department? | 36 |
| Larger-than-life statue of a Civil War general? | 47 |
| Larger-than-life singer from Hoboken | 36 |
| Largely factual entertainment genre | 35 |
| Large-scale product display event | 33 |
| Large-print word on a sheriff's poster | 42 |
| Large-print edition of the Bible, e.g. | 38 |
| Large-format entertainment choice | 33 |
| Large, water-dwelling salamanders | 33 |
| Large, leaflike part of a flower | 32 |
| Large, fun quantity, in a saying | 32 |
| Large, endangered marine herbivore | 34 |
| Large, brilliantly colored food fish | 36 |
| Large ___ Collider (CERN particle accelerator) | 46 |
| Large wading birds common to the Americas | 41 |
| Large tribe in the United States | 32 |
| Large thing that takes years to mature | 38 |
| Large subfamily of Indo-European languages | 42 |
| Large snake or James Clavell best seller | 40 |
| Large seed of the alligator pear | 32 |
| Large rodent also known as a spotted cavy | 41 |
| Large red hog with drooping ears | 32 |
| Large quantities of laughter, e.g. | 34 |
| Large property size, for residences | 35 |
| Large portion of habitable Earth | 32 |
| Large political campaign contributors | 37 |
| Large pieces detached from icebergs | 35 |
| Large percentage of oneÂ’s grade, generally | 46 |
| Large percentage of one's grade, perhaps | 44 |
| Large parts of some support systems? | 36 |
| Large part of one's grade, generally | 40 |
| Large part of Al-Jazeera's audience | 39 |
| Large part of a waiter's income | 35 |
| Large parrot with brilliant plumage | 35 |
| Large or small, grammatically: Abbr. | 36 |
| Large North American wading bird | 32 |
| Large metal vessel with a handle and spout | 42 |