| Letters denoting "date not set" | 41 |
| Letters denoting "so you know" | 41 |
| Letters decreasingly seen on sunscreen | 38 |
| Letters dating from the third century | 37 |
| Letters concerning available space | 34 |
| Letters by a left-pointing arrow | 32 |
| Letters between a name and a nickname | 37 |
| Letters before Star Trek's Enterprise | 41 |
| Letters before Prince William of Wales | 38 |
| Letters before many a state's name | 38 |
| Letters before Liberty or Constitution | 38 |
| Letters before Jimmy Carter or Ronald Reagan | 44 |
| Letters before Constitution or Lincoln | 38 |
| Letters before Arizona or Missouri | 34 |
| Letters before an intended recipient's name | 47 |
| Letters before an assumed commercial name | 41 |
| Letters before a state name, perhaps | 36 |
| Letters before a second afterthought | 36 |
| Letters before a princess's name | 36 |
| Letters before a phone number maybe | 36 |
| Letters before a phone no., perhaps | 35 |
| Letters before a name on a letter | 33 |
| Letters before a duke's name | 32 |
| Letters before a crook's name, perhaps | 42 |
| Letters before "Friday's" | 39 |
| Letters before "Equal Housing Lender" | 47 |
| Letters before "and sometimes Y" | 42 |
| Letters at the start of a destroyer's name | 46 |
| Letters at the end of some letters | 34 |
| Letters at the end of some business names | 41 |
| Letters at the end of a page, sometimes | 39 |
| Letters at the end of a love letter | 35 |
| Letters at the end of a letter, perhaps | 39 |
| Letters at the beginning of a URL | 33 |
| Letters at least one person will never read | 43 |
| Letters associated with Timothy Leary | 37 |
| Letters associated with Jim and Tammy Faye | 42 |
| Letters associated with Einstein | 32 |
| Letters associated with early space missions | 44 |
| Letters associated with an alias | 32 |
| Letters after some officers' names | 38 |
| Letters after Senator Judd Gregg's name | 43 |
| Letters after Senator Dick Lugar's name | 43 |
| Letters after Senator Dan Coats's name | 42 |
| Letters after Sen. Jeanne Shaheen's name | 44 |
| Letters after Sen. Javits's name | 36 |
| Letters after Sen. D'Amato's name | 41 |
| Letters after Sen. Charles Schumer's name | 45 |
| Letters after representative Jim Walsh's name | 49 |
| Letters after Moynihan's name | 33 |
| Letters after messenger, ribosomal, or transfer | 47 |
| Letters after messenger or transfer | 35 |
| Letters after Kirsten Gillibrand's name | 43 |
| Letters after John Sununu's name | 36 |
| Letters after Gov. Jeanne Shaheen's name | 44 |
| Letters after Daniel Moynihan's name | 40 |
| Letters after a barrister's name | 36 |
| Letters addressed to an airplane, perhaps | 41 |
| Letters accompanying some 2,000-year-old+ dates | 47 |
| Letters above ~, on many keyboards | 34 |
| Letters above some stoas on campus | 34 |
| Letterman's TV program (with "The") | 49 |
| Letterman's Stupid _____ Tricks | 35 |
| Letterman's stupid ___ tricks | 33 |
| Letterman's last guest on NBC | 33 |
| Letterman's "Top Ten," e.g. | 41 |
| Lettering on a cheerleader's sweater | 40 |
| Lettered piece of court evidence | 32 |
| Letterboxing or geocaching, e.g. | 32 |
| Letter-writing prisoner, perhaps | 32 |
| Letter-writing friend from far away | 35 |
| Letter-writer's third afterthought | 38 |
| Letter-writer's afterthoughts | 33 |
| Letter-shaped, threaded fastener | 32 |
| Letter-shaped structural support | 32 |
| Letter-shaped skyscraper support | 32 |
| Letter-shaped opening in some pistons | 37 |
| Letter-shaped opening in a machine shop | 39 |
| Letter-shaped opening for a bolt | 32 |
| Letter-shaped hardware used to strengthen joints | 48 |
| Letter-shaped fastener used in woodworking | 42 |
| Letter-shaped construction support | 34 |
| Letter-shaped construction pieces | 33 |
| Letter-shaped construction piece | 32 |
| Letter-shaped construction girder | 33 |
| Letter-shaped construction component | 36 |
| Letter-shaped bit of NASA equipment | 35 |
| Letter you can read without the light on | 40 |
| Letter written as a straight vertical line | 42 |
| Letter writing, as some would say | 33 |
| Letter writing and blacksmithing | 32 |
| Letter writer's embellishment | 33 |
| Letter writer's afterthoughts | 33 |
| Letter with the largest section in a dictionary | 47 |
| Letter with a limited amount of space | 37 |
| Letter used to represent resistance | 35 |
| Letter used to represent Lagrange multipliers | 45 |
| Letter thought to resemble a skull | 34 |
| Letter that's opened with a double-click | 44 |
| Letter that sounds like a question | 34 |