| Lose ground in the standings | 28 |
| Lose ground, in a Paul Simon song | 33 |
| Lose ground, literally | 22 |
| Lose ground, mentally | 21 |
| Lose ground? | 12 |
| Lose hair | 9 |
| Lose hair, as a dog | 19 |
| Lose heart | 10 |
| Lose hold of | 12 |
| Lose hope | 9 |
| Lose iciness | 12 |
| Lose ignominiously, in slang | 28 |
| Lose in a big way | 17 |
| Lose in a confrontation, maybe | 30 |
| Lose in great amounts | 21 |
| Lose in one's drawers | 25 |
| Lose intensity | 14 |
| Lose intentionally | 18 |
| Lose interest | 13 |
| Lose interest in | 16 |
| Lose it | 7 |
| Lose it all | 11 |
| Lose it and run amok | 20 |
| Lose it completely? | 19 |
| Lose it during a debate | 23 |
| Lose it in the clutch | 21 |
| Lose it, in slang | 17 |
| Lose it, with "out" | 29 |
| Lose it? | 8 |
| Lose its luster | 15 |
| Lose its solidity | 17 |
| Lose liquidity | 14 |
| Lose little by little | 21 |
| Lose locks | 10 |
| Lose luster | 11 |
| Lose minutes | 12 |
| Lose moisture | 13 |
| Lose moisture, in a way | 23 |
| Lose momentarily | 16 |
| Lose momentum | 13 |
| Lose money on "Jeopardy!" | 35 |
| Lose money on "Jeopardy!," e.g. | 41 |
| Lose muscle tone | 16 |
| Lose no games | 13 |
| Lose no time | 12 |
| Lose on "Concentration"? | 34 |
| Lose on purpose | 15 |
| Lose one's aloofness | 24 |
| Lose one's amateur standing | 31 |
| Lose one's amateur status | 29 |
| Lose one's backbone? | 24 |
| Lose one's balance | 22 |
| Lose one's balance? | 23 |
| Lose one's bifocals? | 24 |
| Lose one's blush | 20 |
| Lose one's coat | 19 |
| Lose one's composure | 24 |
| Lose one's cool | 19 |
| Lose one's cool with | 24 |
| Lose one's cool? | 20 |
| Lose one's footing | 22 |
| Lose one's grip | 19 |
| Lose one's grip on | 22 |
| Lose one's grip? | 20 |
| Lose one's head | 19 |
| Lose one's head big-time? | 29 |
| Lose one's hearing | 22 |
| Lose one's heart | 20 |
| Lose one's identity | 23 |
| Lose one's inhibitions | 26 |
| Lose one's lap | 18 |
| Lose one's marbles | 22 |
| Lose one's mind | 19 |
| Lose one's nerve | 20 |
| Lose one's nerve at the worst possible moment | 49 |
| Lose one's patience with, maybe | 35 |
| Lose one's place? | 21 |
| Lose one's reserve | 22 |
| Lose one's resistance | 25 |
| Lose one's resolve | 22 |
| Lose one's self-control | 27 |
| Lose one's sense of direction? | 34 |
| Lose one's sense of humor | 29 |
| Lose one's shadow, say | 26 |
| Lose one's shirt | 20 |
| Lose one's shirt, in business | 33 |
| Lose one's sunburn | 22 |
| Lose one's tail? | 20 |
| Lose one's tempeer | 22 |
| Lose one's temper | 21 |
| Lose one's temper while watching "127 Hours"? | 59 |
| Lose one's temper with | 26 |
| Lose one's touch | 20 |
| Lose one's train | 20 |
| Lose oneÂ’s footing | 22 |
| Lose oomph | 10 |
| Lose or draw alternative | 24 |
| Lose out | 8 |
| Lose part of a coat | 19 |
| Lose patience and then some | 27 |