| Side in the Peloponnesian War | 29 |
| Side in many a western | 22 |
| Side in classic battles | 23 |
| Side in an Indian restaurant | 28 |
| Side in an epic battle | 22 |
| Side in an age-old battle | 25 |
| Side in a pickup hoops game | 27 |
| Side in a Euro conflict | 23 |
| Side in a criminal case | 23 |
| Side in a Colosseum battle | 26 |
| Side in a classic battle | 24 |
| Side in a 1980's war | 24 |
| Side effect or ride effect? | 27 |
| Side effect of steroid use | 26 |
| Side effect of puberty | 22 |
| Side effect of a withdrawal? | 28 |
| Side effect of a bike helmet | 28 |
| Side dishes, country-style | 26 |
| Side dish with fried clams | 26 |
| Side dish with crabcakes | 24 |
| Side dish with chow mein | 24 |
| Side dish with bangers | 22 |
| Side dish often oven-roasted | 28 |
| Side dish for a hot dog | 23 |
| Side by side, from Latin | 24 |
| Side away from the wind | 23 |
| Side at many barbecues | 22 |
| Siddhartha's surname | 24 |
| Sid's sidekick, once | 24 |
| Sid Caesar's partner | 24 |
| Sics one's lawyer on | 24 |
| Sickout that's a cop-out? | 29 |
| Sicknesses or hardships | 23 |
| Sickness, en Francais | 22 |
| Sickly, as a complexion | 23 |
| Sickens with sweetness | 22 |
| Sickeningly sweet sentiment | 27 |
| Sickening, in a sarcastic way | 29 |
| Sick-and-tired feeling | 22 |
| Sick ___ death (mortally ill) | 29 |
| Sick kid's TLC giver | 24 |
| Sick feeling on campus? | 23 |
| Sicily's Mount ___ | 22 |
| Sicily's Mongibello | 23 |
| Sicily's lava spewer | 24 |
| Sicily's highest point | 26 |
| Sicily's highest peak | 25 |
| Sicily's famous volcano | 27 |
| Sicilian wine used in cooking | 29 |
| Sicilian tourist sight | 22 |
| Sicilian tourist attraction | 27 |
| Sicilian summer resort | 22 |
| Sicilian spouter: var. | 22 |
| Sicilian spouter (Var.) | 23 |
| Sicilian secret society | 23 |
| Sicilian potent potable | 23 |
| Sicilian health resort | 22 |
| Sicilian code of silence | 24 |
| Sicilian city or strait | 23 |
| Sicilian active volcano | 23 |
| Sicilia or Sardinia, e.g. | 25 |
| Sichuan cooking ingredient | 26 |
| Sic transit gloria ___ | 22 |
| Siblings' daughters | 23 |
| Siblings' biz abbr. | 23 |
| Siblings or Western outlaws | 27 |
| Siblings may engage in them | 27 |
| Siblings may engage in it | 25 |
| Sibling's nickname | 22 |
| Sibling's issue, perhaps | 28 |
| Sibling's daughters | 23 |
| Sibling's daughter | 22 |
| Sibling studio of Screen Gems | 29 |
| Sibling of un frère | 22 |
| Sibling of Peter Rabbit | 23 |
| Sibling of Moses and Miriam | 27 |
| Sibling of Amy and Meg | 22 |
| Sibilant sound of derision | 26 |
| Sibilant attention-getters | 26 |
| Sibilant attention-getter | 25 |
| Sibilant attention getter | 25 |
| Sibilant "Hey!" | 25 |
| Sibilant "Ahem!" | 26 |
| Siberians' relatives | 24 |
| Siberians' burdens | 22 |
| Siberian or slippery ___ | 24 |
| Siberian industrial center | 26 |
| Siberian forest region | 22 |
| Siberian "no" | 23 |
| Sibelius and Saarinen? | 22 |
| Siamese's poor relative | 27 |
| Siamese sign of contentment | 27 |
| Siamese or Persian, e.g. | 24 |
| Siamese for "Aah!"? | 29 |
| Siamese employee, once | 22 |
| Siamese "please" | 26 |
| SI unit named for a Serb | 24 |
| Si across the Pyrenees | 22 |
| Shyster's next-of-kin | 25 |
| Shylock's practice | 22 |