| Sister island of Nevis | 22 |
| Sister in an Eastwood film | 26 |
| Sister in a film title | 22 |
| Sister in a Chekhov play | 24 |
| Sister in "Sisters" | 29 |
| Sister goddess of Calliope | 26 |
| Sister Eileen's state | 25 |
| Sister company of Zipcar | 24 |
| Sister co. of Applebee's | 28 |
| Sister city of St. Petersburg | 29 |
| Sister city of El Paso | 22 |
| Sister channel of Starz | 23 |
| Sister channel of Cinemax | 25 |
| Sister channel of Chiller | 25 |
| Sister chain of Hardee's | 28 |
| Sister brand of Swatch | 22 |
| Sister brand of Snapple | 23 |
| Sister brand of Doritos | 23 |
| Sister brand of CorningWare | 27 |
| Sister brand of Beneful | 23 |
| Sister brand of Armor All | 25 |
| Sister Bertrille, e.g. | 22 |
| Sister and wife of Zeus | 23 |
| Sister and wife of Osiris | 25 |
| Sister and wife of Hyperion | 27 |
| Sissy's biopic role | 23 |
| Sissy who's not a sissy | 27 |
| Sissy Spacek title role | 23 |
| Sissy of "Carrie" | 27 |
| Sisqo's group ___ Hill | 26 |
| Siskel's TV partner | 23 |
| Siskel reaction, sometimes | 26 |
| Sisal processing plant | 22 |
| Sisal and Bombay, e.g. | 22 |
| Sis, boom, bah's kin | 24 |
| Sirs' counterparts | 22 |
| Sirs of the lowest rank | 23 |
| SiriusXM subscriber, say | 24 |
| Sirius XM Radio CEO Karmazin | 28 |
| Sirius merged with it in 2008 | 29 |
| Sirius and Vega, notably | 24 |
| Sirius and Antares, for two | 27 |
| Sires, as in the Bible | 22 |
| Sirens announce their arrival | 29 |
| Sirenian seen off Fla. | 22 |
| Siren-sounding vehicle | 22 |
| Siren, according to myth | 24 |
| Siren sound, in the comics | 26 |
| Siren or angler, at times | 25 |
| Siren irritates prison head? | 28 |
| Siren heard on the Rhine? | 25 |
| Sired, in Biblical times | 24 |
| Sired, in biblical terms | 24 |
| Sire, biblically speaking | 25 |
| Sire's counterpart | 22 |
| Sire of five top race horses | 28 |
| Sir, on the subcontinent | 24 |
| Sir, in colonial India | 22 |
| Sir's coun-terpart | 22 |
| Sir Willoughby Patterne, e.g. | 29 |
| Sir William Wallace, for one | 28 |
| Sir Walter, the novelist | 24 |
| Sir Walter ___ (author) | 23 |
| Sir Walter Scott novel | 22 |
| Sir Walter Scott classic | 24 |
| Sir Walter Scott character | 26 |
| Sir Walter Raleigh quest | 24 |
| Sir Thomas, the writer | 22 |
| Sir Thomas, tea merchant | 24 |
| Sir Thomas More, in Jordan | 26 |
| Sir Thomas the conductor | 25 |
| Sir Robert's monuments | 26 |
| Sir Robert Peel, notably | 24 |
| Sir Robert Peel, for one | 24 |
| Sir Richard of The Tatler | 25 |
| Sir Patrick of balladry | 23 |
| Sir Patrick of ballad fame | 26 |
| Sir or ma'am preceder | 25 |
| Sir Michael, the actor | 22 |
| Sir Lancelot's protection | 29 |
| Sir Lancelot's armor | 24 |
| Sir James Galway, e.g. | 22 |
| Sir James Dewar, for one | 24 |
| Sir James Biggers character | 27 |
| Sir Herbert Beerbohm ___ | 24 |
| Sir Henry's gallery | 23 |
| Sir Henry ____ (Hotspur) | 24 |
| Sir Henry ___ (Hotspur) | 23 |
| Sir Henry Wotton's Rx? | 26 |
| Sir Henry Irving, e.g. | 22 |
| Sir Hardwicke or Ceballos | 25 |
| Sir Gerald du ___ of stage | 26 |
| Sir Geraint's wife | 22 |
| Sir Georg with a baton | 22 |
| Sir Georg Solti's gp. | 25 |
| Sir Galahad's mother | 24 |
| Sir Galahad's armor | 23 |
| Sir Frederick Ashton ballet | 27 |
| Sir Freddie of Skytrain | 23 |
| Sir Francis of the high seas | 28 |