| Lead role in a 60's TV drama | 32 |
| Lead role in a classic Arthur Miller play | 41 |
| Lead role in producers Max and Leo's musical | 48 |
| Lead role in Rimsky-Korsakov's "The Maid of Pskov" | 64 |
| Lead role in the film "La Cage aux Folles" | 52 |
| Lead role in the film known in France as "L'Or de la Vie" | 71 |
| Lead role on "Providence" | 35 |
| Lead role on TV's "Providence" | 44 |
| Lead seeker: Abbr. | 18 |
| Lead sharer | 11 |
| Lead singer | 11 |
| Lead singer for the Belmonts | 28 |
| Lead singer for The Wailers | 27 |
| Lead singer in No Doubt's hit "Don't Speak" | 61 |
| Lead singer in the band Heart | 29 |
| Lead singer Michaels of Poison | 30 |
| Lead singer of Buzzcocks | 24 |
| Lead singer of Led Zeppelin | 27 |
| Lead singer of Pearl Jam | 24 |
| Lead singer of rock's Foo Fighters | 38 |
| Lead singer of the band Body Count | 34 |
| Lead singer of the band whose name is derived from a "Barbarella" villain's name | 94 |
| Lead singer of The Cars | 23 |
| Lead singer of the Doors | 24 |
| Lead singer of the fictional Pussycats | 38 |
| Lead singer of the Irish rock group The Corrs | 45 |
| Lead singer of the Isley Brothers | 33 |
| Lead singer of the Kinks | 24 |
| Lead singer of the Main Ingredient | 34 |
| Lead singer of The Miracles | 27 |
| Lead singer of U2 | 17 |
| Lead singer on "Octopus's Garden" | 47 |
| Lead singer with Dawn | 21 |
| Lead singer with The Police | 27 |
| Lead singer's spot | 22 |
| Lead single from The Smashing Pumpkins' "Gish" | 60 |
| Lead Soprano | 12 |
| Lead Soprano? | 13 |
| Lead source | 11 |
| Lead speaker | 12 |
| Lead splitter | 13 |
| Lead statistic | 14 |
| Lead strip joining glass panes | 30 |
| Lead substitute | 15 |
| Lead sulfide | 12 |
| Lead the bidding | 16 |
| Lead the billing | 16 |
| Lead the cast | 13 |
| Lead the cast of | 16 |
| Lead the life of ___ | 20 |
| Lead the life ___ | 17 |
| Lead the meeting | 16 |
| Lead the nomad's life | 25 |
| Lead the orchestra | 18 |
| Lead the pack | 13 |
| Lead the pack, e.g. | 19 |
| Lead the way | 12 |
| Lead to | 7 |
| Lead to a result | 16 |
| Lead to a seat, informally | 26 |
| Lead to a seat, slangily | 24 |
| Lead to dash or happy | 21 |
| Lead to mislead, in bridge | 26 |
| Lead to the altar | 17 |
| Lead to the exit | 16 |
| Lead tool | 9 |
| Lead up the aisle | 17 |
| Lead used for sounding | 22 |
| Lead voice in "Up" | 28 |
| Lead watchdog: abbr. | 20 |
| Lead weight | 11 |
| Lead weights | 12 |
| Lead wild horse using vehicles! | 31 |
| Lead window rods | 16 |
| Lead __: EPA concern | 20 |
| Lead ___ | 8 |
| Lead ___ life | 13 |
| Lead ___-and-dog life (constantly quarrel) | 42 |
| Lead's counterpart | 22 |
| Lead's principal ore | 24 |
| Lead, as a committee | 20 |
| Lead, as a department | 21 |
| Lead, as a work group | 21 |
| Lead, e.g. | 10 |
| Lead, for example | 17 |
| Lead, for one | 13 |
| Lead, heavy and bit | 19 |
| Lead, often | 11 |
| Lead, perhaps | 13 |
| Lead, say | 9 |
| Lead-and-tin alloy | 18 |
| Lead-colored | 12 |
| Lead-in | 7 |
| Lead-in for short | 18 |
| Lead-in following a second point | 32 |
| Lead-in for ''Bravo'' | 37 |
| Lead-in for ''graph'' | 37 |
| Lead-in for ''graph'' or ''legal'' | 66 |
| Lead-in for ''life'' or ''size'' | 64 |
| Lead-in for ''light'' or ''night'' | 66 |