| Last horse to win the Triple Crown | 34 |
| Last human city in the "Matrix" movies | 48 |
| Last hurrahs | 12 |
| Last in a Greek series | 22 |
| Last in a line | 14 |
| Last in a line of 26 | 20 |
| Last in a lineup | 16 |
| Last in a long line | 19 |
| Last in a mathematical series | 29 |
| Last in a sequence: Abbr. | 25 |
| Last in a series | 16 |
| Last in a series: Abbr. | 23 |
| Last in a theoretical series | 28 |
| Last in a very long line | 24 |
| Last in an indefinite series | 28 |
| Last in an indefinitely numerous series | 39 |
| Last in clarity | 15 |
| Last in line, usually | 21 |
| Last in seq. | 12 |
| Last in the A.L., from 1961 to 1968 | 35 |
| Last in the class | 17 |
| Last in the Julio-Claudian dynasty | 34 |
| Last Incan emperor | 18 |
| Last inning, typically | 22 |
| Last inning, usually | 20 |
| Last innings | 12 |
| Last innings, typically | 23 |
| Last installment of "The Godfather" | 45 |
| Last interminably | 17 |
| Last item | 9 |
| Last item bagged, often: Abbr. | 30 |
| Last item? | 10 |
| Last items | 10 |
| Last Jane Austen novel published while she was alive | 52 |
| Last Jewish month | 17 |
| Last Judgment | 13 |
| Last Julian emperor | 19 |
| Last Julio-Claudian emperor | 27 |
| Last king of a united Israel, in the Bible | 42 |
| Last king of a united Sweden and Norway | 39 |
| Last king of Albania | 20 |
| Last king of Egypt | 18 |
| Last king of Israel | 19 |
| Last king of the united Sweden and Norway | 41 |
| Last king of Troy | 17 |
| Last lap efforts | 16 |
| Last layer of paint | 19 |
| Last leftover | 13 |
| Last leg | 8 |
| Last leg of a race | 18 |
| Last leg of a relay | 19 |
| Last leg of the Ironman Triathlon | 33 |
| Last leg runner | 15 |
| Last letter | 11 |
| Last letter at Cambridge | 24 |
| Last letter found in London | 27 |
| Last letter from Greece | 23 |
| Last letter from London | 23 |
| Last letter in "Boz" | 30 |
| Last letter in communications lingo | 35 |
| Last letter in England | 22 |
| Last letter in June, e.g. | 25 |
| Last letter in Leeds | 20 |
| Last letter in London | 21 |
| Last letter in London? | 22 |
| Last letter in most plurals (but not in this puzzle's six longest answers, which are the only plurals in this grid) | 119 |
| Last letter in radio lingo | 26 |
| Last letter in the first third of the Greek alphabet | 52 |
| Last letter of a pilot's alphabet | 37 |
| Last letter of the Hebrew alphabet | 34 |
| Last letter of the Hebrew alphabet, similar to the letter T | 59 |
| Last letter, across the pond | 28 |
| Last letter, in Leeds | 21 |
| Last letter, in London | 22 |
| Last letter, in some places | 27 |
| Last letter, in South Africa | 28 |
| Last letter, to British | 23 |
| Last letter? | 12 |
| Last letters | 12 |
| Last letters appropriate for October's last day | 51 |
| Last letters from London | 24 |
| Last letters in Lincolnshire | 28 |
| Last letters in London | 22 |
| Last letters of a farm refrain | 30 |
| Last letters of a math proof | 28 |
| Last letters on some lists | 26 |
| Last letters, appropriately | 27 |
| Last letters, in Britain | 24 |
| Last letters, in England | 24 |
| Last letters? | 13 |
| Last licks | 10 |
| Last line | 9 |
| Last line in a riddle | 21 |
| Last line of "Jaws" | 29 |
| Last line of "lament" | 31 |
| Last line of "Star Trek: First Contact" | 49 |
| Last line of defense | 20 |
| Last line of many a riddle | 26 |
| Last line of quip | 17 |
| Last line of some riddles | 25 |