| What often does it? | 19 |
| What often comes with a twist? | 30 |
| What Oedipus solved | 19 |
| What odes do | 12 |
| What octothorpes may represent | 30 |
| What ochlophobists fear | 23 |
| What ochlophobes fear | 21 |
| What occurs on a trip to the laundromat? | 40 |
| What obsolete things fall into | 30 |
| What obfuscators lack | 21 |
| What Obama was shooting in that one picture | 43 |
| What Obama is called, often | 27 |
| What Oasis stressed "The Importance of Being" | 55 |
| What O.S. means in prescriptions for glasses | 44 |
| What O. J. gains | 16 |
| What O'Neill wields | 23 |
| What O'Neill called "Dat ole davil" | 49 |
| What O'Hara's Joey was | 30 |
| What O may mean | 15 |
| What nyctophobes fear | 21 |
| What nut's from Tippecanoe? | 31 |
| What nuns take | 14 |
| What numbers after some colons represent | 40 |
| What nudniks do | 15 |
| What nudity may lead to | 23 |
| What NOW wants women to be | 26 |
| What NOW wants now | 18 |
| What Novocain creates | 21 |
| What novices don't know | 27 |
| What nouns and verbs must do | 28 |
| What notorious 1999 computer virus was named after an exotic dancer? | 68 |
| What not to yell in a crowded theater | 37 |
| What not to touch something with | 32 |
| What not to sweat | 17 |
| What not to see, hear or speak | 30 |
| What not to rock or miss | 24 |
| What not to rock | 16 |
| What not to get in | 18 |
| What not to get from the boss | 29 |
| What not to do to Superman's cape | 37 |
| What not to do before December 25? | 34 |
| What not to call Bryn Mawr | 26 |
| What not even the richest person on Earth has | 45 |
| What North and South Dakota do | 30 |
| What nonparallel lines do eventually | 36 |
| What none of the teams in this puzzle play | 42 |
| What non-ticket-holders do to gate | 34 |
| What non-swimmers do | 20 |
| What nomads hit? | 16 |
| What nomads do | 14 |
| What Nolan Ryan does | 20 |
| What Nolan Ryan became in 1979 | 30 |
| What nods signify | 17 |
| What nods often mean | 20 |
| What nods may mean | 18 |
| What nobody likes to pay | 24 |
| What nobody doesn't like | 28 |
| What Noah's neighbors needed | 32 |
| What Noah Webster said ...? | 27 |
| What Noah saved for a rainy day? | 32 |
| What Noah counted by? | 21 |
| What Noah counted by | 20 |
| What Noah built the Ark for | 27 |
| What no-show musician went | 26 |
| What no one has while standing | 30 |
| What no one did on Genesis hit? | 31 |
| What no Mensa member has | 24 |
| What no man is? | 15 |
| What no man is | 14 |
| What no insurance company wants to sell? | 40 |
| What no band wants from fans | 28 |
| What Nixon said he was not | 26 |
| What Nixon denied being | 23 |
| What Nixon and Kennedy have in common? | 38 |
| What nitrous oxide produces | 27 |
| What nitpickers split | 21 |
| What Nirvana will do to a "Pen Cap"? | 46 |
| What Nick Lowe puts his rocks in? | 33 |
| What Nichols makes | 18 |
| What NHL shootouts resolve | 26 |
| What news networks claim to lack | 32 |
| What newly signed rockers are happy as | 38 |
| What newbies read online | 24 |
| What newbies read on-line | 25 |
| What new parents lose | 21 |
| What new moms of twins need? | 28 |
| What new hotshot does to bar | 28 |
| What new guy did to former guy's shoes | 42 |
| What New Englanders call "tonic" | 42 |
| What never lets go? | 19 |
| What Ness put people under | 26 |
| What nervous Nellies are on | 27 |
| What nerve, disrupting a carpenter's joint with that kind of hat (3-6) | 74 |
| What neophytes show to experts | 30 |
| What nearly everyone works for | 30 |
| What nearby stores may be "within" | 44 |
| What NBC's peacock once signified | 37 |
| What navel oranges lack | 23 |
| What Nature abhors | 18 |
| What naturals have | 18 |