| Experimental musician Brian | 27 |
| Brian of ambient music fame | 27 |
| Producer of seven U2 albums | 27 |
| Musician and producer Brian | 27 |
| Artsy renaissance man Brian | 27 |
| Ambient music's creator | 27 |
| "Neroli" musician | 27 |
| Long-stemmed white mushroom | 27 |
| Chemical ending or compound | 27 |
| Compound with a double bond | 27 |
| Part of a famous plane name | 27 |
| "Waterworld" girl | 27 |
| First name on a WWII bomber | 27 |
| First name on a 1945 bomber | 27 |
| Part of a bomber's name | 27 |
| First name of a famed plane | 27 |
| Adam and Eve's grandson | 27 |
| Cooperstown's Slaughter | 27 |
| 1980's TV police comedy | 27 |
| Stan the Man's teammate | 27 |
| Seth's son in the Bible | 27 |
| One-time Cardinal Slaughter | 27 |
| One of Adam's grandsons | 27 |
| Musician Brian's family | 27 |
| First grandson in the Bible | 27 |
| First family's grandson | 27 |
| 1961 "spacechimp" | 27 |
| Disturbed song that had it? | 27 |
| Sufficient, for Shakespeare | 27 |
| This used to be sufficient? | 27 |
| Fortify with vitamins, e.g. | 27 |
| Register for classes (Var.) | 27 |
| Register for a class (Var.) | 27 |
| Sign up for an online class | 27 |
| Texas-based scandal subject | 27 |
| Houston's old ___ Field | 27 |
| Professor Higgins, to Eliza | 27 |
| Eliza's tutor, to Eliza | 27 |
| Nearly half of ninety-nine? | 27 |
| Start of nothing and nobody | 27 |
| Spaces used by typographers | 27 |
| Second lt.'s equivalent | 27 |
| Officer on a PT boat: Abbr. | 27 |
| Naval Academy grad. (Abbr.) | 27 |
| Naval acad. grad's rank | 27 |
| Infantry officer, for short | 27 |
| Couple in "Annie" | 27 |
| Midshipman, upon graduation | 27 |
| Preserve, as tons of fodder | 27 |
| Pioneer Expressionist James | 27 |
| Attached, as hôtel rooms | 27 |
| Sinus specialist, for short | 27 |
| Multipurpose doc, for short | 27 |
| Suffix with exist or insist | 27 |
| Allergy specialist, perhaps | 27 |
| Tinnitus treater, for short | 27 |
| Rhinology expert, for short | 27 |
| Otolaryngologist, for short | 27 |
| M.D. concerned with tonsils | 27 |
| Ending with insist or exist | 27 |
| Ending for differ or insist | 27 |
| Apnea specialist, for short | 27 |
| International understanding | 27 |
| Arrangement between nations | 27 |
| Triple ___ of 1907–8 | 27 |
| "Door's open" | 27 |
| Tall key on a keypad, often | 27 |
| "Come in" command | 27 |
| First word of many a script | 27 |
| Carriage return, these days | 27 |
| Signed up for, as a contest | 27 |
| Follow the script, in a way | 27 |
| Responds to a cue, in a way | 27 |
| Dangle a carrot in front of | 27 |
| Opposite of "exo" | 27 |
| Group in a star's orbit | 27 |
| Building's surroundings | 27 |
| ___'acte (intermission) | 27 |
| ---'acte (intermission) | 27 |
| Fancy word for intermission | 27 |
| Broadway album instrumental | 27 |
| What wrestlers use rock for | 27 |
| Student selection criterion | 27 |
| Potential winner at Belmont | 27 |
| _____-temps (interval): Fr. | 27 |
| Chef's special, usually | 27 |
| "Specials," often | 27 |
| Tolkien's talking trees | 27 |
| Battle of Isengard warriors | 27 |
| Wooden creatures of fantasy | 27 |
| Wizards of aahs, for short? | 27 |
| Tolkien's forest giants | 27 |
| Tolkein's forest giants | 27 |
| Forest of Fangorn creatures | 27 |
| Accustom to hardship (Var.) | 27 |
| Cause to become hardened to | 27 |
| Become accustomed to (Var.) | 27 |
| Make immune, as to violence | 27 |
| Unsolicited manuscript enc. | 27 |
| Stationer's item: Abbr. | 27 |