| So quiet you could hear ___ drop | 32 |
| So unexpected as to have not been imagined | 42 |
| SO WE BOUGHT A BUSINESS JUST ___ | 32 |
| So, so dope, with "tha" | 33 |
| So-called "African unicorn" | 37 |
| So-called "baby busters" | 34 |
| So-called "ballet of the masses" | 42 |
| So-called "Chinese gelatin" | 37 |
| So-called "City of Victory" | 37 |
| So-called "cradle of civilization" | 44 |
| So-called "dance of love" | 35 |
| So-called "Father of Europe" | 38 |
| So-called "Gateway to Australia" | 42 |
| So-called "Giant Brain" of 1946 | 41 |
| So-called "Goddess of Pop" | 36 |
| So-called "good cholesterol," for short | 49 |
| So-called "Heart of Texas" | 36 |
| So-called "Helen of the West Indies" | 46 |
| So-called "Hippie Chocolate" | 38 |
| So-called "king of herbs" | 35 |
| So-called "King of Vibes" | 35 |
| So-called "kissing disease," for short | 48 |
| So-called "Land of the Gods" | 38 |
| So-called "Little Flower of Jesus" | 44 |
| So-called "lowest form of humor" | 42 |
| So-called "lowest form of wit" | 40 |
| So-called "miracle plant" | 35 |
| So-called "nerves" while putting | 42 |
| So-called "penguin suit" | 34 |
| So-called "Playwright of the Midwest" | 47 |
| So-called "potted physician" | 38 |
| So-called "royal herb" | 32 |
| So-called "Songbird of the South" | 43 |
| So-called "style moderne" | 35 |
| So-called "Texas White House," once | 45 |
| So-called "Valley Isle" | 33 |
| So-called "wand of heaven" | 36 |
| So-called "weekend pill" | 34 |
| So-called "Wheat Capital of Oklahoma" | 47 |
| So-called "white magic" | 33 |
| So-called "Wizard of Odds" | 36 |
| So-called Birthplace of Aviation | 32 |
| So-called devil's darning needles [2000] | 44 |
| So-called kissing disease, familiarly | 37 |
| So-far-undiscovered ones, briefly | 33 |
| Soaked in hot water, as a tea bag | 33 |
| Soaks (up), as with a paper towel | 33 |
| Soap Box Derby championship state | 33 |
| Soap brand containing ground pumice | 35 |
| Soap company getting into auto accessory? | 41 |
| Soap for a member of Bill Haley's group? | 44 |
| Soap opera comic strip set in a hospital | 40 |
| Soap opera lover's favorite food? | 37 |
| Soap opera set in a body-treatment business? | 44 |
| Soap opera set in a California wine region | 42 |
| Soap opera that premiered in 1956 | 33 |
| Soap operas or movie thrillers, say | 35 |
| Soap substitutes, in the Southwest | 34 |
| Soap title character of the 1970's | 38 |
| Soap whose first slogan was "It floats" | 49 |
| Soap writer hatches a plot about an Iranian coin? | 49 |
| Soapmaker's substances, perhaps | 35 |
| Sobieski of 'Joan of Arc' | 33 |
| Sobieski of "Joan of Arc" | 35 |
| Sobieski of "Joy Ride" (2001) | 39 |
| Sobriety checkpoint target, for short | 37 |
| Sobriquet for a Houston Rockets star | 36 |
| Sobriquet for a mimic suffering stage fright? | 45 |
| Sobriquet for Charles V, with "the" | 45 |
| Sobriquet for singer John Phillips | 34 |
| Sobriquet for the 2007 MLB home run leader | 42 |
| Sobriquet for Wayne, Jon, or Kim | 32 |
| Sobriquet for William Henry Harrison | 36 |
| Soccer feature in Buddhist lands? | 33 |
| Soccer mom's "nothing" | 36 |
| Soccer mom's wheels, stereotypically | 40 |
| Soccer player Suárez known to bite opponents | 47 |
| Soccer player who does the least running | 40 |
| Soccer player who scored his first goal at age 14 | 49 |
| Soccer player's jersey, for short | 37 |
| Soccer players who can use their hands | 38 |
| Soccer rarity, it sometimes seems | 33 |
| Soccer star David committed a hand ball? | 40 |
| Soccer star who wrote "Go for the Goal" | 49 |
| Soccer star with his name on a video game title | 47 |
| Soccer star's broadcast medium? | 35 |
| Soccer star's favorite type of shoe? | 40 |
| Soccer team nicknamed the Black-and-Red | 39 |
| Soccer team on which phenom Freddy Adu plays | 44 |
| Soccer's Edson Arantes do Nascimento | 40 |
| Soccer-playing wife of baseball player Nomar | 44 |
| Social activity on a military base? | 35 |
| Social butterfly's flower pot? | 34 |
| Social crème de la crème | 38 |
| Social D "___ Between Heaven and Hell" | 48 |
| Social D "___ of My Life" | 35 |
| Social Distortion "___ Be Me" | 39 |
| Social Distortion singer/guitarist Mike | 39 |
| Social division of Hindu society | 32 |
| Social events at which dominoes are worn | 40 |