| It's due when it's doubled | 34 |
| It's dull | 13 |
| It's dull and painful | 25 |
| It's dull, it's said | 28 |
| It's duller than cobalt | 27 |
| It's dynamite | 17 |
| It's dynamite stuff | 23 |
| It's e. of South Sudan | 26 |
| It's earned | 15 |
| It's earned for a degree | 28 |
| It's earned for bringing someone home: Abbr. | 48 |
| It's earned on the street, briefly | 38 |
| It's earned toward a degree | 31 |
| It's earthshaking | 21 |
| It's easily erased | 22 |
| It's easily perused | 23 |
| It's easily upset | 21 |
| It's east of Alabama | 24 |
| It's east of Calif. | 23 |
| It's east of Colombia's northernmost point | 50 |
| It's east of Des Moines | 27 |
| It's east of Eden | 21 |
| It's east of Europe | 23 |
| It's east of Ill. | 21 |
| It's east of Indiana | 24 |
| It's east of Java | 21 |
| It's east of Mayfair | 24 |
| It's east of Miss. | 22 |
| It's east of N.A. | 21 |
| It's east of Oregon | 23 |
| It's east of Penna. | 23 |
| It's east of Pol. | 21 |
| It's east of the Atl. | 25 |
| It's east of the Bering Strait | 34 |
| It's east of the Caspian | 28 |
| It's east of the Great Barrier Reef | 39 |
| It's east of the Isle of Man: Abbr. | 39 |
| It's east of the Urals | 26 |
| It's east of Yucatán | 27 |
| It's easy | 13 |
| It's easy as 1-2-3 | 22 |
| It's easy as pie | 20 |
| It's easy to burn | 21 |
| It's easy to do if you brought a headset, hard if your batteries died | 73 |
| It's easy to do if you're hungry, hard if it's late and the shops have closed | 89 |
| It's easy to do if you're not traveling alone, hard if you're surrounded by strangers | 97 |
| It's easy to do if you've got a book, hard if kids are bugging you | 74 |
| It's easy to do with the right connections, hard if you can't find a good hotspot | 89 |
| It's easy to do....well, it's just easy to do | 53 |
| It's easy to get down from them | 35 |
| It's easy to miss | 21 |
| It's easy to skin | 21 |
| It's easy to swallow | 24 |
| It's eaten in Eastern Europe | 32 |
| It's eaten pod and all | 26 |
| It's eaten up, so to speak | 30 |
| It's eaten with a cracker | 29 |
| It's edible | 15 |
| It's educational, according to The Pixies | 45 |
| It's effective only when fired | 34 |
| It's effective when it gets in hot water | 44 |
| It's eight hours later than PST | 35 |
| It's eight hrs. later than PST | 34 |
| It's either positive or negative | 36 |
| It's electric | 17 |
| It's electric, perhaps | 26 |
| It's electrified at the Olympics | 36 |
| It's elegant when turned | 28 |
| It's elementary | 19 |
| It's elementary, to Watson | 30 |
| It's embarrassing to eat | 28 |
| It's embarrassing to make one | 33 |
| It's empty | 14 |
| It's endangered | 19 |
| It's ENE of Cleveland | 25 |
| It's ENE of Fiji | 20 |
| It's enforced by les gendarmes | 34 |
| It's enough for Luigi | 25 |
| It's enough for some | 24 |
| It's enough to bring a tear to the eye | 42 |
| It's enough to make you cry | 31 |
| It's enough to prevent a strike | 35 |
| It's enough to take you for a ride | 38 |
| It's enough, according to some | 34 |
| It's enough, for some | 25 |
| It's enough, in an expression | 33 |
| It's enough, it's said | 30 |
| It's entered and processed | 30 |
| It's entered before a delivery | 34 |
| It's entered before a password | 34 |
| It's entered in a courtroom | 31 |
| It's entered in court | 25 |
| It's entirely represented in this puzzle grid | 49 |
| It's enveloped in white | 27 |
| It's equal to 100 ergs per gram | 35 |
| It's equal to 43,560 square feet | 36 |
| It's equivalent to 40-30 | 28 |
| It's equivalent to C | 24 |
| It's ere noon | 17 |
| It's eschewed by vegans | 27 |