| Lose consciousness | 18 |
| Lose color, in a way | 20 |
| Lose color, as jeans | 20 |
| Lose color in the wash | 22 |
| Lose color | 10 |
| Lose clout | 10 |
| Lose capacity for growth | 24 |
| Lose by design | 14 |
| Lose brilliancy | 15 |
| Lose brilliance | 15 |
| Lose brightness | 15 |
| Lose breadth | 12 |
| Lose big time | 13 |
| Lose big | 8 |
| Lose balance | 12 |
| Lose badly | 10 |
| Lose at the bank? | 17 |
| Lose at poker, perhaps | 22 |
| Lose at blackjack | 17 |
| Lose at a dice game (with "out") | 42 |
| Lose an outrageous bet? | 23 |
| Lose an opportunity | 19 |
| Lose altitude | 13 |
| Lose all patience | 17 |
| Lose all one's money in gambling | 36 |
| Lose all hope | 13 |
| Lose all control | 16 |
| Lose alertness | 14 |
| Lose air, as a tire | 19 |
| Lose after going all-in | 23 |
| Lose acuity | 11 |
| Lose a token in pinball | 23 |
| Lose a sunburn | 14 |
| Lose a suit? | 12 |
| Lose a staring contest | 22 |
| Lose a member | 13 |
| Lose a lot? | 11 |
| Lose a liking for | 17 |
| Lose a layer | 12 |
| Lose a lap? | 11 |
| Lose a lap | 10 |
| Lose a few pounds | 17 |
| Lose a coat? | 12 |
| Lose a coat | 11 |
| Lose (to) | 9 |
| Lose as power | 14 |
| Lose | 4 |
| Los _____, Calif. | 17 |
| Los _____ | 9 |
| Los ____: atomic city | 21 |
| Los ____ | 8 |
| Los ___, of A-bomb fame | 23 |
| Los ___, New Mexico | 19 |
| Los ___, N.M. | 13 |
| Los ___, Ecuadorean province | 28 |
| Los ___, California | 19 |
| Los ___, Calif. | 15 |
| Los ___, A.E.C. property | 24 |
| Los ___ Unidos | 14 |
| Los ___ Reyes Magos | 19 |
| Los ___ National Laboratory | 27 |
| Los ___ mosqueteros | 19 |
| Los ___ de los Muertos (Mexican holiday) | 40 |
| Los ___ (seat of Valencia County, New Mexico) | 45 |
| Los ___ (nuclear site) | 22 |
| Los ___ (Manhattan Project site) | 32 |
| Los ___ (Manhattan Project lab site) | 36 |
| Los ___ ("La Bamba" band) | 35 |
| Los ___ | 7 |
| Los __: Manhattan Project site | 30 |
| Los __: city near San Jose | 26 |
| Los __: Bay Area city | 21 |
| Los __, NM | 10 |
| Los __, city near San Luis Obispo | 33 |
| Los __ (Silicon Valley city) | 28 |
| Los __ | 6 |
| Los Pollos Hermanos businessman Fring on TV's "Breaking Bad" | 74 |
| Los Palominos' music | 24 |
| Los Juegos OlÃmpicos prize | 29 |
| Los hermanos de la madre | 24 |
| Los follower | 12 |
| Los del ___ ("Macarena" duo) | 38 |
| Los Del ___ ("Macarena" band) | 39 |
| Los del Rio's lone hit | 26 |
| Los Angeles-to-San Bernardino direction | 39 |
| Los Angeles-based ISP | 21 |
| Los Angeles, for one | 20 |
| Los Angeles's ___-Sinai Medical Center | 42 |
| Los Angeles's ___ Verdes Peninsula | 38 |
| Los Angeles's ___ Tower | 27 |
| Los Angeles's ___ Museum | 28 |
| Los Angeles's ___ College of Art and Design | 47 |
| Los Angeles's U.S.S. ___ Museum | 35 |
| Los Angeles's San ___ Bay | 29 |
| Los Angeles's La ___ Tar Pits | 33 |
| Los Angeles' San ___ Bay | 28 |
| Los Angeles woe | 15 |
| Los Angeles weather surprise | 28 |
| Los Angeles tourist draw | 24 |
| Los Angeles Times piece, e.g. | 29 |