| Loss of voice | 13 |
| Loss of value: Abbr. | 20 |
| Loss of the sense of smell | 26 |
| Loss of the certifiable | 23 |
| Loss of the ability to read | 27 |
| Loss of speech | 14 |
| Loss of speaking ability | 24 |
| Loss of skilled personnel | 25 |
| Loss of serve in volleyball | 27 |
| Loss of sense of smell | 22 |
| Loss of self-control | 20 |
| Loss of reputation | 18 |
| Loss of rank | 12 |
| Loss of power to use or understand words | 40 |
| Loss of power to understand words | 33 |
| Loss of power | 13 |
| Loss of points | 14 |
| Loss of nerve, metaphorically | 29 |
| Loss of muscle coordination | 27 |
| Loss of mental power | 20 |
| Loss of memory | 14 |
| Loss of juice | 13 |
| Loss of heart | 13 |
| Loss of hair | 12 |
| Loss of function | 16 |
| Loss of footing for a jockey? | 29 |
| Loss of feeling | 15 |
| Loss of faculties | 17 |
| Loss of diligence | 17 |
| Loss of crew, maybe? | 20 |
| Loss of courage, slangily | 25 |
| Loss of courage | 15 |
| Loss of confidence | 18 |
| Loss of color | 13 |
| Loss of breath | 14 |
| Loss of bodily sensation | 24 |
| Loss of ability to understand | 29 |
| Loss of ability to read | 23 |
| Loss of a word's ending | 27 |
| Loss of a stripe | 16 |
| Loss of 1588 | 12 |
| Loss mitigator | 14 |
| Loss leaders? | 13 |
| Loss leader? | 12 |
| Loss leader, e.g. | 17 |
| Loss leader | 11 |
| Loss indicator | 14 |
| Loss from a guillotine | 22 |
| Loss for a Tibetan pup? | 23 |
| Loss due to leaks | 17 |
| Loss caused by emigration for profit | 36 |
| Loss by decay | 13 |
| Loss by #1, say | 15 |
| Loss at a bald spot | 19 |
| Loss | 4 |
| Losing, as gains | 16 |
| Losing, after "on" | 28 |
| Losing World Series manager of the 1933 Senators and the 1946 Red Sox | 69 |
| Losing weight | 13 |
| Losing ventures? | 16 |
| Losing tribe in the Beaver Wars | 31 |
| Losing trends? | 14 |
| Losing tic-tac-toe row | 22 |
| Losing tic-tac-toe line, perhaps | 32 |
| Losing tic-tac-toe line | 23 |
| Losing tic-tac-toe combo | 24 |
| Losing the fuzz? | 16 |
| Losing team in Super Bowl XXXIV | 31 |
| Losing Super Bowl XIV team member | 33 |
| Losing string | 13 |
| Losing streaks | 14 |
| Losing streak stopper, often | 28 |
| Losing streak breaker, say | 26 |
| Losing streak | 13 |
| Losing straw in drawing straws | 30 |
| Losing strategy? | 16 |
| Losing strategy, for short | 26 |
| Losing strategy | 15 |
| Losing strategies | 17 |
| Losing steam | 12 |
| Losing side in a 2000 Supreme Court ruling | 42 |
| Losing schemes | 14 |
| Losing scheme | 13 |
| Losing sch. in the second Sugar Bowl | 36 |
| Losing runs | 11 |
| Losing row | 10 |
| Losing rolls | 12 |
| Losing roll in a casino | 23 |
| Losing racer | 12 |
| Losing purposely | 16 |
| Losing propositions? | 20 |
| Losing propositions | 19 |
| Losing proposition? | 19 |
| Losing proposition | 18 |
| Losing power, like a battery | 28 |
| Losing power | 12 |
| Losing position? | 16 |
| Losing popularity | 17 |
| Losing poker hand | 17 |
| Losing player in the 2005 World Series | 38 |