| Irish __ | 8 |
| Irish ___ | 9 |
| Irish ____ | 10 |
| Irish _____ | 11 |
| Irish _____ Prince Edward Island special crop | 47 |
| Irish, e.g. | 11 |
| Irish, for one | 14 |
| Irish-born actor Milo | 21 |
| Irish-born actor whose character in "Barbarella" inspired the band name Duran Duran | 93 |
| Irish-born actress McKenna | 26 |
| Irish-born player John of Manchester United | 43 |
| Irish-born Tony winner Patrick | 30 |
| Irish-Gaelic | 12 |
| Irish-Sea isle | 14 |
| Irish-stew ingredient | 21 |
| Irish-themed Vegas casino | 25 |
| Irish-themed Vegas casino that features a tattoo parlor owned by Mötley Crüe's Vince Neil | 99 |
| Irish: Abbr. | 12 |
| Irishman | 8 |
| Irishman or Welshman | 20 |
| Irishman or Welshman, e.g. | 26 |
| Irishman who was a Time magazine Person of the Year in 2005 | 59 |
| Irishman's activity on March 17 | 35 |
| Irishman's dance | 20 |
| Irishman's darling | 22 |
| Irishman's expression of surprise | 37 |
| Irishman's home goods store? | 32 |
| Irishman's pride | 20 |
| Irishman, e.g. | 14 |
| Irishman, informally | 20 |
| Irishman: Var. | 14 |
| Irishmen | 8 |
| Irk | 3 |
| Irk greatly | 11 |
| Irk like crazy | 14 |
| Irk one's sweetheart? | 25 |
| Irk the man upstairs | 20 |
| Irk to no end | 13 |
| Irk, and then some | 18 |
| Irk-aholic? | 11 |
| Irked | 5 |
| Irked a lot | 11 |
| Irked reaction | 14 |
| Irked squared | 13 |
| Irked with | 10 |
| Irked, with "off" | 27 |
| Irking insect | 13 |
| Irks | 4 |
| Irks greatly | 12 |
| Irks some? | 10 |
| Irksome | 7 |
| Irksome fellow | 14 |
| Irksome imps | 12 |
| Irksome individual | 18 |
| Irksome one | 11 |
| Irksome ones | 12 |
| Irksome person | 14 |
| Irksome response to "You're avoiding the question" | 64 |
| Irksome sort | 12 |
| Irksome swarm member | 20 |
| Irksome swarmer | 15 |
| Irksome type | 12 |
| Irkutsk river | 13 |
| Irlanda, por ejemplo | 20 |
| Irma who wrote "The Joy of Cooking" | 45 |
| Iron | 4 |
| IRON (6th) | 10 |
| Iron Age Europeans | 18 |
| Iron Age people | 15 |
| Iron Age period | 15 |
| Iron alloy | 10 |
| Iron alternative | 16 |
| Iron and bauxite | 16 |
| Iron and Bronze | 15 |
| Iron and Bronze, e.g. | 21 |
| Iron and Bronze, for two | 24 |
| Iron and copper, e.g. | 21 |
| Iron and Ice | 12 |
| Iron and Industrial | 19 |
| Iron and Middle | 15 |
| Iron and others | 15 |
| Iron and Patty | 14 |
| Iron and Stone | 14 |
| Iron and toaster | 16 |
| Iron and Wine "Resurrection ___" | 42 |
| Iron and zinc | 13 |
| Iron and zinc compounds | 23 |
| Iron anniversary | 16 |
| Iron attachment | 15 |
| Iron attachment? | 16 |
| Iron band | 9 |
| Iron bar | 8 |
| Iron brace | 10 |
| Iron Butterfly "In-A-Gadda-Da-___" | 44 |
| Iron Butterfly "In-A-___-Da-Vida" | 43 |
| Iron Butterfly classic | 22 |
| Iron carbonate | 14 |
| Iron carrier in blood | 21 |
| Iron clothes | 12 |
| Iron clothes? | 13 |