| Instrument hit with a mallet | 28 |
| Instrument honored in a Beaufort, South Carolina, museum | 56 |
| Instrument in 1980s pop music | 29 |
| Instrument in a brass quintet | 29 |
| Instrument in a Chinese temple | 30 |
| Instrument in a Picasso painting | 32 |
| Instrument in a pit | 19 |
| Instrument in a wind quintet | 28 |
| Instrument in an Italian orchestra | 34 |
| Instrument in ancient Greek art | 31 |
| Instrument in backwoods bands | 29 |
| Instrument in hillbilly bands | 29 |
| Instrument in Middle Eastern music | 34 |
| Instrument in much '80s pop | 31 |
| Instrument in NATO's phonetic alphabet | 42 |
| Instrument in need of cleaning? | 31 |
| Instrument in quirky contemporary bands | 39 |
| Instrument in Saul's time | 29 |
| Instrument in Schubert's "Trout Quintet" | 54 |
| Instrument in some baroque pop tunes | 36 |
| Instrument in some old paintings | 32 |
| Instrument in the E Street Band | 31 |
| Instrument in the E-Street Band | 31 |
| Instrument in the woodwind section | 34 |
| Instrument inventor | 19 |
| Instrument Jimmie Lunceford played | 34 |
| Instrument just about anyone can play | 37 |
| Instrument made by the companies Mahalo and Lanikai | 51 |
| Instrument made from African blackwood | 38 |
| Instrument made from African blackwood, often | 45 |
| Instrument made from bamboo | 27 |
| Instrument made from grenadilla | 31 |
| Instrument made in the lab? | 27 |
| Instrument made of turtle shell | 31 |
| Instrument made with a turtle shell | 35 |
| Instrument maker | 16 |
| Instrument maker with a logo of interlocking tuning forks | 57 |
| Instrument maker with an interlocking-tuning-forks logo | 55 |
| Instrument making HI notes? | 27 |
| Instrument measuring elevation | 30 |
| Instrument Meg White hits | 25 |
| Instrument Merrill Garbus of tUnE-yArDs plays, for short | 56 |
| Instrument missing from The White Stripes | 41 |
| Instrument named for its similarity to a chestnut | 49 |
| Instrument near a drum | 22 |
| Instrument not played in the New York Philharmonic? | 51 |
| Instrument of an "angelo" | 35 |
| Instrument of ancient Greece | 28 |
| Instrument of conveyance | 24 |
| Instrument of India | 19 |
| Instrument of Marxism? | 22 |
| Instrument of minute examination | 32 |
| Instrument of revenge | 21 |
| Instrument of thought | 21 |
| Instrument of torture | 21 |
| Instrument of torture in "1984" | 41 |
| Instrument of torture in Room 101 of "1984" | 53 |
| Instrument often accompanied by a pair of small drums | 53 |
| Instrument often described as "mournful" | 50 |
| Instrument often in pairs | 25 |
| Instrument often left hanging | 29 |
| Instrument often made from grenadilla wood | 42 |
| Instrument often made of plastic | 32 |
| Instrument often played while sitting on the floor | 50 |
| Instrument on a Greek vase | 26 |
| Instrument on Irish euros | 25 |
| Instrument on Mariah Carey's "Hero" | 49 |
| Instrument on the Beatles' "Norwegian Wood" | 57 |
| Instrument on the Beatles' "Within You Without You" | 65 |
| Instrument on which Jake Shimabukuro can play "Bohemian Rhapsody" | 75 |
| Instrument once called the hautboy | 34 |
| Instrument Orpheus played | 25 |
| Instrument panel | 16 |
| Instrument panel features | 25 |
| Instrument panel locale | 23 |
| Instrument panel part | 21 |
| Instrument panels | 17 |
| Instrument patented in 1846 | 27 |
| Instrument Paul McCartney played on Ringo Starr's "You're Sixteen" | 84 |
| Instrument played by a hummer | 29 |
| Instrument played by Bach | 25 |
| Instrument played by Bill Wyman | 31 |
| Instrument played by Bleeding Gums Murphy | 41 |
| Instrument played by Bob Burns | 30 |
| Instrument played by George Harrison | 36 |
| Instrument played by Kenny G | 28 |
| Instrument played by Schweitzer | 31 |
| Instrument played in the mouth | 30 |
| Instrument played on "Sgt. Pepper's" | 50 |
| Instrument played on the 2005 White Stripes album "Get Behind Me Satan" | 81 |
| Instrument played sitting down | 30 |
| Instrument played standing up | 29 |
| Instrument played while seated | 30 |
| Instrument played with a bow | 28 |
| Instrument played with a mallet | 31 |
| Instrument played with a plectrum | 33 |
| Instrument played with a spatula | 32 |
| Instrument played with mallets | 30 |
| Instrument played with the mouth | 32 |
| Instrument played with the thumb | 32 |