| It could start with a five o'clock shadow | 45 |
| It offers "penetrating pain relief" | 45 |
| It's softer than tooth, believe it or not | 45 |
| Ichabod's "Sleepy Hollow" rival | 45 |
| It ensues when cooler heads don't prevail | 45 |
| It's three levels below the major leagues | 45 |
| It includes the brain and spinal cord (abbr.) | 45 |
| Internet expert Lawrence Lessig's subject | 45 |
| Inspector Van _____ Valk (literary detective) | 45 |
| It ends when you "fall back": abbr. | 45 |
| It now starts before the end of winter: Abbr. | 45 |
| Ira Levin's "A Kiss Before ___" | 45 |
| Irving Bacheller's "___ Holden" | 45 |
| Irving Bacheller novel "___ Holden" | 45 |
| It's often tested with "Hello!" | 45 |
| It was discontinued after the 1960 model year | 45 |
| It may be on an embarrassed person's face | 45 |
| It may be bruised if you fall down the stairs | 45 |
| Island where Napoleon spent 42 weeks in exile | 45 |
| Isle of ___ (part of Cambridgeshire, England) | 45 |
| Ibsen's "An ___ of the People" | 45 |
| It's over thirty quadrillion seconds long | 45 |
| It lasts between four and five galactic years | 45 |
| Idle who sang "The Lumberjack Song" | 45 |
| It's somewhere in the neighborhood: Abbr. | 45 |
| It's about 10% of the Earth's surface | 45 |
| It stretches from the Atlantic to the Pacific | 45 |
| It paid about 50-1 at the 2007 Kentucky Derby | 45 |
| Israel's defense minister before Menachem | 45 |
| Initials often jokingly redefined on T-shirts | 45 |
| Indie-pop band inspired by flowerless plants? | 45 |
| Its state flower is the orange blossom: Abbr. | 45 |
| It may get jammed under your windshield wiper | 45 |
| It's "Black" once a year: Abbr. | 45 |
| Indians called him the "Great Soul" | 45 |
| It was once divided into East and West: abbr. | 45 |
| Influential pre-Renaissance Florentine artist | 45 |
| Indian tourist destination on the Arabian Sea | 45 |
| If you stop wearing one, you may lose a point | 45 |
| Interrupter of a bad act, on an old game show | 45 |
| Italian-speaking forklift in "Cars" | 45 |
| Its flag has the Union Jack in the upper left | 45 |
| Italian's "pronto" on the phone | 45 |
| It dissolved when Francis II abdicated: Abbr. | 45 |
| It started at the end of the Dark Ages: Abbr. | 45 |
| It's handy if you have to break your word | 45 |
| It flows through the veins of the emotionless | 45 |
| Irving Berlin's 'What'll --?' | 45 |
| It's often close to a soldier's heart | 45 |
| It sells a lot of build-it-yourself furniture | 45 |
| Indian name meaning ''ruler'' | 45 |
| It oversees a major production every two yrs. | 45 |
| Island that's the burial place of Macbeth | 45 |
| Investments for one's golden years, maybe | 45 |
| Its st. song is "Home on the Range" | 45 |
| It starts "In the name of Allah..." | 45 |
| It was last an official Olympic event in 1908 | 45 |
| Is annoyingly slow, as an internet connection | 45 |
| Inspired "Turn On Your Love Light"? | 45 |
| Its flag has a big white circle in the middle | 45 |
| It might be served after lighting the menorah | 45 |
| Inaugural Rock and Roll Hall of Fame inductee | 45 |
| Ira who wrote "Rosemary's Baby" | 45 |
| It's at the end of a tunnel, proverbially | 45 |
| It's glossed over during a make-up class? | 45 |
| It has juicy white flesh in a rough red shell | 45 |
| Italian town, site of a 1796 Napoleon victory | 45 |
| If A > B and B > C, then A > C, e.g. | 45 |
| It was heavily dropped about four decades ago | 45 |
| It greatly improves Animal Collective records | 45 |
| It was originally first on the Roman calendar | 45 |
| It fell shortly after the 2001 vernal equinox | 45 |
| It broke apart over the South Pacific in 2001 | 45 |
| It's across the Pailolo Channel from Maui | 45 |
| It might beat a dead horse, but not much else | 45 |
| iPod with a 1.5-inch Multi-Touch color screen | 45 |
| Its official languages are English and French | 45 |
| It becomes aquatic during its breeding season | 45 |
| Its "Welcome to" sign is a gold pan | 45 |
| It's often given two weeks before leaving | 45 |
| Intel collector hidden in nine puzzle answers | 45 |
| Island called "The Gathering Place" | 45 |
| Its ''A'' tunes the orchestra | 45 |
| Instrument made from African blackwood, often | 45 |
| It was heard three times at the 2004 Olympics | 45 |
| It consists of a concave and a convex segment | 45 |
| Its national emblem includes a khanjar dagger | 45 |
| It's dialed before a long-distance number | 45 |
| Inductee to the Hockey Hall of Fame at age 31 | 45 |
| Italian song that won Pavarotti a 1980 Grammy | 45 |
| It puts the "hot" in hot cross buns | 45 |
| Its maker claims it won a blue ribbon in 1893 | 45 |
| It's mightier than the sword, in a saying | 45 |
| Implement for an experienced crossword solver | 45 |
| In ___, you might see some ___ hanging around | 45 |
| Israel's first native-born prime minister | 45 |
| Its Old World Style label has a gondola on it | 45 |
| Indian friend of TV's Sheldon and Leonard | 45 |
| Increase one's home's value, in a way | 45 |
| Illinois birthplace of William Jennings Bryan | 45 |