| South American mammals | 22 |
| South American lowlands | 23 |
| South American liberator | 24 |
| South American invention | 24 |
| South American herd members | 27 |
| South American grilling style | 29 |
| South American grassland | 24 |
| South American forest dweller | 29 |
| South American fleece source | 28 |
| South American fiber plant | 26 |
| South American fellow? | 22 |
| South American empire of yore | 29 |
| South American cruise stop | 26 |
| South American creature | 23 |
| South American country | 22 |
| South American constrictor | 26 |
| South American coastal region | 29 |
| South American civilization | 27 |
| South American celebration | 26 |
| South American cattle-catcher | 29 |
| South American cattle catcher | 29 |
| South American carrier | 22 |
| South American carnivores | 25 |
| South American cardinal? | 24 |
| South American capital | 22 |
| South American border lake | 26 |
| South American arboreal snake | 29 |
| South American aboriginals | 26 |
| South American aboriginal | 25 |
| South AmericaÂ’s Rio ___ | 27 |
| South America's ___ Trail | 29 |
| South African writer Fugard | 27 |
| South African weaverbird | 24 |
| South African villages | 22 |
| South African village: Var. | 27 |
| South African tribesman | 23 |
| South African township | 22 |
| South African succulent | 23 |
| South African statesman Jan | 27 |
| South African statesman | 23 |
| South African settlement | 24 |
| South African province | 22 |
| South African president Zuma | 28 |
| South African prelate Desmond | 29 |
| South African politico | 22 |
| South African peninsula | 23 |
| South African pen for animals | 29 |
| South African Peace Nobelist | 28 |
| South African Nobelist | 22 |
| South African native village | 28 |
| South African monetary unit | 27 |
| South African monarchy | 22 |
| South African metropolis | 24 |
| South African links man | 23 |
| South African liberator | 23 |
| South African language group | 28 |
| South African language | 22 |
| South African iris cousin | 25 |
| South African herbal drink | 26 |
| South African headgear? | 23 |
| South African grassland | 23 |
| South African golfing great | 27 |
| South African golfer Els | 24 |
| South African golf pro | 22 |
| South African enclosure | 23 |
| South African Dutchman | 22 |
| South African currency units | 28 |
| South African currency unit | 27 |
| South African currency | 22 |
| South African colonist | 22 |
| South African author Alan | 25 |
| South African assembly | 22 |
| South African antelopes | 23 |
| South African antelope | 22 |
| South African activist Biko | 27 |
| South African activist | 22 |
| South Africa-to-Egypt dir. | 26 |
| South Africa's _____ Paul | 29 |
| South Africa's ___ Paul | 27 |
| South Africa's president | 28 |
| South Africa's Mandela | 26 |
| South Africa's first P.M. | 29 |
| South Africa has a famous one | 29 |
| South Africa 2010 chant | 23 |
| South Pacific island | 22 |
| South American wood sorrels | 28 |
| Souter's predecessor | 24 |
| Souter's colleague | 22 |
| Souse's woe, for short | 26 |
| Sousaphones' relatives | 26 |
| Sousaphone, for example | 23 |
| Sousaphone's relative | 25 |
| Sousaphone's cousin | 23 |
| Sousa or Alexander, e.g. | 24 |
| Sous chef's gadget | 22 |
| Sourpuss's expression | 25 |
| Sourish bakery offerings | 24 |
| Sourdoughs' purses | 22 |
| Sourdoughs' concerns | 24 |
| Sourdough, quite possibly | 25 |