| Founder of the Portuguese empire in the East | 44 |
| Founder of the Rothschild dynasty | 33 |
| Founder of the royal house of Lancaster | 39 |
| Founder of the Shakers in America | 33 |
| Founder of the Shakers in the U.S. | 34 |
| Founder of the Shakers, in America | 34 |
| Founder of the Stoic school of philosophy | 41 |
| Founder of the U.K.'s Poetry Book Society | 45 |
| Founder of Time, Life, and Fortune | 34 |
| Founder of United We Stand America | 34 |
| Founder's successor, at times | 33 |
| Founder's successor, in some cases | 38 |
| Founding editor of The New Yorker | 33 |
| Founding family in a Metalious novel | 36 |
| Founding Father listed on a popular computer? | 45 |
| Founding father Richard Henry ___ | 33 |
| Founding father who had a beer named after him | 46 |
| Founding member of a 60's-80's pop trio | 47 |
| Founding member of the Arab League | 34 |
| Founding member of the Justice League | 37 |
| Founding member of the Star Alliance, for short | 47 |
| Founding member of the Washington Freedom | 41 |
| Founding of a hip replacement clinic? | 37 |
| Founding owner of the Pittsburgh Steelers | 41 |
| Founding Scorpions member Schenker | 34 |
| Founding Stones pianist (nickname) | 34 |
| Founding Stones pianist Ian (abbr.) | 35 |
| Foundry workers' mind-reading? | 34 |
| Fountain designed by Nicola Salvi | 33 |
| Fountain featured in "La Dolce Vita" | 46 |
| Fountain in front of the Palazzo Poli | 37 |
| Fountain of Youth site, it's said | 37 |
| Fountain treat with cherries on top | 35 |
| Four after ''paper'' | 36 |
| Four and twenty blackbirds (and 76 more) | 40 |
| Four couples expect big argument | 32 |
| Four enter them, but only two survive | 37 |
| Four groups found in this puzzle | 32 |
| Four home runs in a single game, e.g. | 37 |
| Four Horsemen's milieu: Abbr. | 33 |
| Four imperial bushels, in England | 33 |
| Four Monopoly properties (abbr.) | 32 |
| Four Monopoly properties, for short | 35 |
| Four more "hot" followers | 35 |
| Four O'Clock is a brand of it | 33 |
| Four o'clock serving, perhaps | 33 |
| Four of a decathlon's 10 events | 35 |
| Four p.m. to midnight, to factory workers | 41 |
| Four parts gin one part vermouth | 33 |
| Four pills instead of the recommended two | 41 |
| Four properties on a Monopoly bd. | 33 |
| Four Seasons hit, "Save ___ Me" | 41 |
| Four Seasons Hotels headquarters | 32 |
| Four SeasonsÂ’ hotel competitor | 34 |
| Four sights as "Hamlet" ends | 38 |
| Four stops on "A" trip around the world | 49 |
| Four strikeouts by a batter in a single game | 44 |
| Four times a day, in prescriptions | 34 |
| Four Tops "It's the ___ Old Song" | 47 |
| Four Tops singer's soaking spots? | 37 |
| Four Tops-inspired Mudvayne song? | 33 |
| Four Wheeler's 2009 SUVs of the Year | 40 |
| Four words with strings attached | 32 |
| Four years, for a U.S. president | 32 |
| Four-act play by George Bernard Shaw | 36 |
| Four-and-twenty blackbirds' place | 37 |
| Four-day weekend time, for many: Abbr. | 38 |
| Four-F's opposite, in the draft | 35 |
| Four-footed adventurer from Kansas | 34 |
| Four-footer on the Neverland ranch | 34 |
| Four-handed piano piece by a French emperor? | 44 |
| Four-legged "Born Free" star | 38 |
| Four-legged Emerald City visitor | 32 |
| Four-legged film star of the '30s | 37 |
| Four-legged film star of the 1930s | 34 |
| Four-legged mascot in college sports | 36 |
| Four-legged nursemaid in "Peter Pan" | 46 |
| Four-poster's little brother | 32 |
| Four-sided monument named for a Greek god | 41 |
| Four-string instruments, for short | 34 |
| Four-stringed Hawaiian instrument, briefly | 42 |
| Four-stringed instrument, briefly | 33 |
| Four-stringed instrument, for short | 35 |
| Four-stringed instruments, briefly | 34 |
| Four-stringed island instruments | 32 |
| Four-stringed orchestral instrument | 35 |
| Four-stroke internal-combustion engine inventor | 47 |
| Four-time 1980s Stanley Cup champs | 34 |
| Four-time A.L. home run champ Griffey Jr. | 41 |
| Four-time A.L. home run champ Jimmie | 36 |
| Four-time ABA/NBA MVP, familiarly | 33 |
| Four-time AL Hank Aaron Award winner | 36 |
| Four-time AL stolen base champion Crawford | 42 |
| Four-time all-pro NFL linebacker | 32 |
| Four-time All-Pro Patriots receiver Welker | 42 |
| Four-time all-star catcher Santiago | 35 |
| Four-time Aussie champ at Wimbledon | 35 |
| Four-time Australian Open champ Goolagong | 41 |
| Four-time Australian Open winner | 32 |
| Four-time Australian Open winner Monica | 39 |