| One ... | 7 |
| One --- customer | 16 |
| One -- time | 11 |
| One -- million | 14 |
| One -- kind | 11 |
| One -- customer | 15 |
| One - one of perhaps many | 25 |
| One + one? | 10 |
| One + one, to Burns | 19 |
| One (Pref.) | 11 |
| One (Ger.) | 10 |
| One "with no invisible means of support": Sheen | 57 |
| One "whose faulty vision sees things as they are, not as they ought to be": Bierce | 92 |
| One "who intimately lives with rain," in a poem | 57 |
| One "trapped by his sinful talk," in Proverbs | 55 |
| One "Tarzan" portrayer | 32 |
| One "tamed" in Shakespeare | 36 |
| One "T" of TNT | 24 |
| One "standing by the ocean's roar," in a 1963 song | 64 |
| One "Pac-Man" ghost | 29 |
| One "out" in la la land | 33 |
| One "little woman" | 28 |
| One "in the woods" | 28 |
| One "in de cold, cold ground" | 39 |
| One "hissed" in a melodrama | 37 |
| One "fair of face" | 28 |
| One "E" on a scoreboard | 33 |
| One "coming" in a Three Dog Night hit | 47 |
| One "caught" on grainy film | 37 |
| One "C" in C.C.C. | 27 |
| One "born free" | 25 |
| One "B" of B&B | 28 |
| One "Arab Spring" nation | 34 |
| One "a-leaping" in a Christmas song | 45 |
| One 'twixt 12 and 20 | 24 |
| One ''A'' in Paris | 34 |
| One ___ (sandlot game) | 23 |
| One to Juan | 12 |
| One in Paris | 13 |
| One in Oaxaca | 14 |
| One in Essen | 13 |
| One in Bonn | 12 |
| One in Berlin | 14 |
| One in Arles | 13 |
| One | 3 |
| Oncoming | 8 |
| Oncology procedure | 18 |
| Oncologist's suggestion | 27 |
| Oncologist's suffix | 23 |
| Oncle's wife | 16 |
| Oncle's spouse | 18 |
| Oncle's relative | 20 |
| Oncle's partner | 19 |
| Oncle's mate | 16 |
| Oncle's counterpart | 23 |
| Once: Lat. | 10 |
| Once: Ger. | 10 |
| Once/a time go-between | 22 |
| Once-___ (quick examinations) | 29 |
| Once-___ (quick appraisals) | 27 |
| Once-worshipped white wader | 27 |
| Once-worshiped white wader | 26 |
| Once-while link | 15 |
| Once-wedded ones | 16 |
| Once-ubiquitous shoe retailer | 29 |
| Once-ubiquitous black-on-yellow image | 37 |
| Once-trendy Hollywood workout routine | 37 |
| Once-stylish footwear | 21 |
| Once-seedy section of NYC | 25 |
| Once-scandalous exposure | 24 |
| Once-sacred snakes | 18 |
| Once-sacred snake | 17 |
| Once-sacred slitherers | 22 |
| Once-sacred reptiles | 20 |
| Once-sacred coilers | 19 |
| Once-rare Sunday sights | 23 |
| Once-promising failures | 23 |
| Once-prominent Arby's competitor | 36 |
| Once-pricey flyers | 18 |
| Once-powerful republic of NW Italy | 34 |
| Once-popular street liners | 26 |
| Once-popular song | 17 |
| Once-popular Olds | 17 |
| Once-popular feather source | 27 |
| Once-popular diet soft drink, or part of the can | 48 |
| Once-popular diet | 17 |
| Once-popular computers | 22 |
| Once-popular coiffure | 21 |
| Once-popular children's TV character | 40 |
| Once-popular anesthetic | 23 |
| Once-over giver | 15 |
| Once-named | 10 |
| Once-mighty initials | 20 |
| Once-ler's foe | 18 |
| Once-in-a-lifetime trip, for some | 33 |
| Once-in-a-lifetime traveler | 27 |
| Once-in-a-lifetime pilgrimage | 29 |
| Once-in-a-lifetime exchange, maybe | 34 |
| Once-in-a-lifetime | 18 |
| Once-in-a-blue-moon events | 26 |