| One next to you on a plane, e.g. | 32 |
| One next to a bishop | 20 |
| One next in line | 16 |
| One newton per square meter | 27 |
| One new to a line | 17 |
| One never stooping | 18 |
| One never seen in "Peanuts" | 37 |
| One never seen in ''Peanuts'' | 45 |
| One network that reaired "Family Guy" | 47 |
| One needing three more wins to become champ | 43 |
| One needing tech support | 24 |
| One needing social work? | 24 |
| One needing rehab | 17 |
| One needing pressure to perform well | 36 |
| One needing parts | 17 |
| One needing no advice | 21 |
| One needing kisses, say | 23 |
| One needing discipline | 22 |
| One needing detox | 17 |
| One needing an att. | 19 |
| One needing a lift | 18 |
| One needing a fence? | 20 |
| One needed to bestow a blessing on a golf club? | 47 |
| One nearing adulthood | 21 |
| One NCO | 7 |
| One napping | 11 |
| One named Sam wants YOU! | 24 |
| One named in a will | 19 |
| One named after "Here's to" | 41 |
| One name for Ursa Minor | 23 |
| One name for a heart test | 25 |
| One name Archie called Meathead | 31 |
| One N.L. team's insignia | 28 |
| One N.B.A. All-Star Game team | 29 |
| One must touch it to score | 26 |
| One must be quick to join it | 28 |
| One musical Gershwin | 20 |
| One mushed | 10 |
| One multiplying by dividing | 27 |
| One Mrs. Trump | 14 |
| One moving earth underwater | 27 |
| One moves before the king | 25 |
| One motivated to change | 23 |
| One more: Abbr. | 15 |
| One more, in Orizaba | 20 |
| One more try on the set | 23 |
| One more try on a set | 21 |
| One more time | 13 |
| One more than tri- | 18 |
| One more than tri | 17 |
| One more than thrice L | 22 |
| One more than the number of different letters in this puzzle | 60 |
| One more than sieben | 20 |
| One more than septi- | 20 |
| One more than penta- | 20 |
| One more than due | 17 |
| One more than cinque | 20 |
| One more than bi- | 17 |
| One more than a birdie | 22 |
| One more than "tri" | 29 |
| One more than "bi" | 28 |
| One more than ''zwei'' | 38 |
| One more likely to default | 26 |
| One more is a crowd | 19 |
| One more | 8 |
| One monitoring a joint | 22 |
| One modifying goals? | 20 |
| One mode of travel | 18 |
| One mode of transportation | 26 |
| One moaning and groaning after a defeat | 39 |
| One mo' time | 16 |
| One mixing with Jim, Jack and Johnny? | 37 |
| One missing roll call, perhaps | 30 |
| One missing 2011-12 preseason games, at least | 45 |
| One minute to one | 17 |
| One minus one | 13 |
| One minding the baby | 20 |
| One mimicking | 13 |
| One millionth of a meter | 24 |
| One million, for example | 24 |
| One million million | 19 |
| One million millennia | 21 |
| One million dollars, to some | 28 |
| One million chiliads | 20 |
| One million bytes, for short | 28 |
| One military stint after another? | 33 |
| One mile, for Denver | 20 |
| One might work with dogs | 24 |
| One might want to settle it | 27 |
| One might wake you up if your window is open | 44 |
| One might wait in front of a church | 35 |
| One might use a life line | 25 |
| One might take it for a drive | 29 |
| One might take classes to manage it | 35 |
| One might swing | 15 |
| One might surround a charismatic person | 39 |
| One might support a foundation | 30 |
| One might stop a strike | 23 |
| One might stand up in court | 27 |
| One might stand in a chamber of horrors | 39 |