| One of the five related names in this puzzle | 44 |
| One of the five Olympic rings | 29 |
| One of the Five Nations | 23 |
| One of the five major taste sensations | 38 |
| One of the five major circles of latitude | 41 |
| One of the five interrogatives | 30 |
| One of the Five Civilized Nations | 33 |
| One of the five chief cities of the Philistines | 47 |
| One of the five Beijing Olympics mascots | 40 |
| One of the five basic tastes | 28 |
| One of the five basic taste sensations | 38 |
| One of the five "Greats" | 34 |
| One of the five "cities of the plain" in Genesis | 58 |
| One of the five | 15 |
| One of the Fitzgeralds | 22 |
| One of the first TV superstations | 33 |
| One of the first TV cartoon serials | 35 |
| One of the first to raise a hand, usually | 41 |
| One of the first spring blooms | 30 |
| One of the first ships to arrive in America | 43 |
| One of the first people mentioned in Genesis | 44 |
| One of the First Daughters | 26 |
| One of the first crooners | 25 |
| One of the first computers | 26 |
| One of the first Buicks to roll off the line? | 45 |
| One of the first Apple personal computers to use a mouse | 56 |
| One of the fire signs | 21 |
| One of the fingers | 18 |
| One of the Finger Lakes | 23 |
| One of the finest | 17 |
| One of the finches | 18 |
| One of the financial markets, for short | 39 |
| One of the filmmaking Coens | 27 |
| One of the filmmaking Coen brothers | 35 |
| One of the film-making Coens | 28 |
| One of the Fijis | 16 |
| One of the fighting Alis | 24 |
| One of the Feds | 15 |
| One of the Fates | 16 |
| One of the Farrelly brothers | 28 |
| One of the family | 17 |
| One of the fam | 14 |
| One of the faithful | 19 |
| One of the fairies | 18 |
| One of the Fab Four | 19 |
| One of the F.F.V. | 17 |
| One of the exchanges, for short | 31 |
| One of the ex-Yalies | 20 |
| One of the Ewings, on "Dallas" | 40 |
| One of the Ewings on "Dallas" | 39 |
| One of the Ewings | 17 |
| One of the Everlys | 18 |
| One of the Everly Brothers | 26 |
| One of the Estevez brothers | 27 |
| One of the estates | 18 |
| One of the Es in E.E.: abbr. | 28 |
| One of the epochs | 17 |
| One of the Epistles | 19 |
| One of the Ephrons | 18 |
| One of the English gentry | 25 |
| One of the enemy | 16 |
| One of the ends of the earth? | 29 |
| One of the empires | 18 |
| One of the elite | 16 |
| One of the electorate | 21 |
| One of the eight vegetables in V8 | 33 |
| One of the eight states bordering Tenn. | 39 |
| One of the eight in V8 | 22 |
| One of the Easts | 16 |
| One of the Eastern elite | 24 |
| One of the East Indies | 22 |
| One of the Earps | 16 |
| One of the Earp brothers | 24 |
| One of the Eagles | 17 |
| One of the Dwarfs | 17 |
| One of the Dutch Masters | 24 |
| One of the Dutch Antilles | 25 |
| One of the Durbeyfields | 23 |
| One of the Durants who wrote "The Story of Civilization" | 66 |
| One of the Durants | 18 |
| One of the Dumas family | 23 |
| One of the Dumas | 16 |
| One of the du Ponts | 19 |
| One of the Dryads | 17 |
| One of the Dow Jones Industrials | 32 |
| One of the Dow Jones 30 | 23 |
| One of the Doodlebops | 21 |
| One of the Donald's exes | 28 |
| One of the Dolomites | 20 |
| One of the Dodge boys? | 22 |
| One of the Dixie Chicks or the Brontës | 41 |
| One of the Dioscuri | 19 |
| One of the Dionnes, for short | 29 |
| One of the Dionnes | 18 |
| One of the Dionne quintuplets | 29 |
| One of the Dionne quints | 24 |
| One of the Dionne five | 22 |
| One of the DiMaggios | 20 |
| One of the dictionary definitions of 122-5-74-84-42: A woman who is ___ | 71 |
| One of the Detroit Pistons' "Bad Boys" of the 1990s | 65 |