| One of the only 12 letter words that typists can produce with just the left hand on a standard keyboard | 103 |
| One of the ones waiting in "Waiting for Godot" | 56 |
| One of the Olsen twins | 22 |
| One of the Olsen sisters | 24 |
| One of the oldest materials for roofs | 37 |
| One of the oldest forms of dress | 32 |
| One of the oil companies: Abbr. | 31 |
| One of the official languages of the Northwest Territories | 58 |
| One of the official languages of Pakistan | 41 |
| One of the official languages of India | 38 |
| One of the oceans: Abbr. | 24 |
| One of the Oceanids | 19 |
| One of the Oceanides, in Greek myth | 35 |
| One of the Oceanides | 20 |
| One of the Obamas | 17 |
| One of the Obama girls | 22 |
| One of the Obama daughters | 26 |
| One of the Oasis brothers | 25 |
| One of the O'Neills | 23 |
| One of the North Africans | 25 |
| One of the noble metals | 23 |
| One of the noble gases | 22 |
| One of the Nixons | 17 |
| One of the nitrites | 19 |
| One of the nine Muses | 21 |
| One of the nightshade family | 28 |
| One of the Nielsen brothers | 27 |
| One of the Niagara River's sources | 38 |
| One of the NFL Mannings | 23 |
| One of the news media | 21 |
| One of the newly rich | 21 |
| One of the New Hebrides | 23 |
| One of the networks | 19 |
| One of the Netherlands Antilles | 31 |
| One of the Nereids in Greek myth | 32 |
| One of the Nereids | 18 |
| One of the Nelsons | 18 |
| One of the Nehru Planetarium cities | 35 |
| One of the Near Islands | 23 |
| One of the nations led by Satan in Revelation | 45 |
| One of the muskrats in the 1976 hit "Muskrat Love" | 60 |
| One of the Musketeers | 21 |
| One of the musical Three B's | 32 |
| One of the musical Jackson brothers | 35 |
| One of the musical Guthries | 27 |
| One of the musical B's | 26 |
| One of the music industry's former Big Four | 47 |
| One of the music industry's Big Four | 40 |
| One of the Muses | 16 |
| One of the Muppets | 18 |
| One of the Munsters of 60's TV | 34 |
| One of the Munsters | 19 |
| One of the Mudville players on base when the mighty Casey struck out | 68 |
| One of the Ms. Pac-Man ghosts | 29 |
| One of the Mrs. Sinatras | 24 |
| One of the moveable feasts | 26 |
| One of the Morgans | 18 |
| One of the moreporks | 20 |
| One of the more vicious fishes | 30 |
| One of the more benign of the seven dirty words | 47 |
| One of the moons of Uranus | 26 |
| One of the moods | 16 |
| One of the Monty Python troupe | 30 |
| One of the Montagues | 20 |
| One of the Monkees | 18 |
| One of the Mongolias | 20 |
| One of the Moluccas | 19 |
| One of the Mohicans | 19 |
| One of the Mitchells in an old UPN sitcom | 41 |
| One of the misfits | 18 |
| One of the Minors | 17 |
| One of the Minor Prophets | 25 |
| One of the midday-sun seekers | 29 |
| One of the mice in "Cinderella" | 41 |
| One of the metalloids | 21 |
| One of the Mercury Seven | 24 |
| One of the Menendez brothers | 28 |
| One of the men waiting in "Waiting for Godot" | 55 |
| One of the men on "Two and a Half Men" | 48 |
| One of the men behind bars | 26 |
| One of the media: Var. | 22 |
| One of the media: Abbr. | 23 |
| One of the media | 16 |
| One of the McCartneys | 21 |
| One of the Mayos in the Land of Lakes | 37 |
| One of the Mayberry gang | 24 |
| One of the Maxwells | 19 |
| One of the Mavericks | 20 |
| One of the Maverick brothers | 28 |
| One of the Maunas | 17 |
| One of the Masseys | 18 |
| One of the masses | 17 |
| One of the Masons | 17 |
| One of the Marxes | 17 |
| One of the Marx brothers | 24 |
| One of the Martins | 18 |
| One of the martial arts | 23 |
| One of the Marshall Islands' 29 | 35 |
| One of the Marshall Islands | 27 |
| One of the Marsalis brothers | 28 |