| One out of prison | 17 |
| One out of his element | 22 |
| One out of fashion | 18 |
| One out of a hundred: abbr. | 27 |
| One out of 10? | 14 |
| One out front: Abbr. | 20 |
| One out for blood | 17 |
| One out for a buck? | 19 |
| One out early | 13 |
| One out | 7 |
| One ornamenting | 15 |
| One ordered to take two tablets | 31 |
| One ordered to stop? | 20 |
| One ordered to have a stroke | 28 |
| One orbit around the sun | 24 |
| One or two, ironically | 22 |
| One or two, e.g. | 16 |
| One or two vehicles? | 20 |
| One or two spreads? | 19 |
| One or two of them often make a lot | 35 |
| One or two game implements? | 27 |
| One or two carriers? | 20 |
| One or two bucks | 16 |
| One or two beverages? | 21 |
| One or two | 10 |
| One or twenty, e.g. | 19 |
| One or thing starter | 20 |
| One or the other | 16 |
| One or some | 11 |
| One or side | 11 |
| One or more prefix | 18 |
| One or more preceder | 20 |
| One or more ancient Egyptian kings | 34 |
| One or more | 11 |
| One or false | 12 |
| One or eleven in blackjack | 26 |
| One or eleven | 13 |
| One or another | 14 |
| One or 11, in blackjack | 23 |
| One option for Hamlet | 21 |
| One opposed to empire building | 30 |
| One opposed | 11 |
| One opinionated to a fault | 26 |
| One operating a loom | 20 |
| One opening up a can of worms? | 30 |
| One opening a manual | 20 |
| One opening a jail door, say | 28 |
| One opening a can of worms? | 27 |
| One open to baseless charges? | 29 |
| One only in it for the money | 28 |
| One online | 10 |
| One one-hundredth of a newton | 29 |
| One one's toes | 18 |
| One once at Brown, e.g. | 23 |
| One once again | 14 |
| One on-line | 11 |
| One on your side | 16 |
| One on your block | 17 |
| One on whom to put the blame, according to a song in "Gilda" | 70 |
| One on whom subtlety is lost | 28 |
| One on watch | 12 |
| One on two feet | 15 |
| One on the wing | 15 |
| One on the way up? | 18 |
| One on the way up | 17 |
| One on the way to a promotion? | 30 |
| One on the way out | 18 |
| One on the way in | 17 |
| One on the way | 14 |
| One on the watch | 16 |
| One on the verge of croaking? | 29 |
| One on the verge of a breakdown? | 32 |
| One on the stump | 16 |
| One on the stick | 16 |
| One on the Statue of Liberty is almost three feet long | 54 |
| One on the staff? | 17 |
| One on the square | 17 |
| One on the sidelines | 20 |
| One on the same squad | 21 |
| One on the same side | 20 |
| One on the run? | 15 |
| One on the run | 14 |
| One on the rolls: Abbr. | 23 |
| One on the road | 15 |
| One on the rise | 15 |
| One on the receiving end | 24 |
| One on the range | 16 |
| One on the platform | 19 |
| One on the payroll | 18 |
| One on the outside of a skyscraper, perhaps | 43 |
| One on the other side | 21 |
| One on the opposing side | 24 |
| One on the offensive | 20 |
| One on the move | 15 |
| One on the Mohs scale | 21 |
| One on the links | 16 |
| One on the left | 15 |
| One on the Lee side? | 20 |
| One on the lam, perhaps | 23 |
| One on the lam | 14 |