| "Is that a fact" | 26 |
| "Is that a fact?!" | 28 |
| "Is that a fact?" | 27 |
| "Is that a guarantee?" | 32 |
| "Is that a gun in your pocket, or are you just happy to see me?," e.g. | 80 |
| "Is that a new man you're dating?" | 48 |
| "Is that a promise?" | 30 |
| "Is that a vampire bat?" | 34 |
| "Is that a yes or ___?" | 33 |
| "Is that a __?" | 25 |
| "Is that a ___?" | 26 |
| "Is that all right with you?" | 39 |
| "Is that all right?" | 30 |
| "Is That All There Is" singer | 39 |
| "Is that an order?" | 29 |
| "Is that clear?" | 26 |
| "Is that it?" | 23 |
| "Is that possible?" | 29 |
| "Is that really my bill?!" | 36 |
| "Is that really true about me?" | 41 |
| "Is that right?" | 26 |
| "Is that seat ___?" | 29 |
| "Is that so much ___?" | 32 |
| "Is that so!" | 23 |
| "Is that so?!" | 24 |
| "Is that so?" | 23 |
| "Is that so?" in IMs | 30 |
| "Is that someone I should know?" | 42 |
| "Is that the case?" | 29 |
| "Is that true about me?" | 34 |
| "Is that what you expected?" | 38 |
| "Is that you as a baby?" | 34 |
| "Is that your final answer?" | 38 |
| "Is that your final ___?" | 35 |
| "Is THAT your game?" | 30 |
| "Is that your __ answer?" | 35 |
| "Is that __?" | 23 |
| "Is that ___?!" | 25 |
| "Is that ___?" | 24 |
| "Is that ___?" ("Really?") | 46 |
| "Is that ___?" ("You don't say!") | 57 |
| "Is that _____?" ("You don't say!") | 59 |
| "Is the defense ___ to proceed?" | 42 |
| "Is the gamble worth it?" | 35 |
| "Is the water ___ drink?" | 35 |
| "Is there -- hope?" | 29 |
| "Is there ---?" (query to Sajak) | 42 |
| "Is there a Brit in the house?" alternative? | 54 |
| "Is there a problem?" | 31 |
| "Is there an ___ in here?" | 36 |
| "Is there any group I haven't offended?" satirist | 63 |
| "Is there any way for me to get out of this?" | 55 |
| "Is there anyone here I haven't offended?" comic | 62 |
| "Is there anyone ___?" | 32 |
| "Is there anything ___?" | 34 |
| "Is there beauty ___?": Dostoyevsky | 45 |
| "Is There Life Out There" singer | 42 |
| "Is There Life Out There" singer Reba | 47 |
| "Is there more to the story?" | 39 |
| "Is there more to this than you care to ___, ___?" | 60 |
| "Is there more?" | 26 |
| "Is there no balm in ___?" | 36 |
| "Is there no ___ this?" | 33 |
| "Is there something more?" | 36 |
| "Is there __ against that?" | 37 |
| "Is there ___ your deception?" | 40 |
| "Is there ___?" | 25 |
| "Is this a dagger which I see ___?" | 45 |
| "Is this a dagger which ___ . . . " | 45 |
| "Is this a dagger which ___ . . . ": Macbeth | 54 |
| "Is this a dagger which ___ . . . ?" | 46 |
| "Is this a dagger ___": Macbeth | 41 |
| "Is this a ___ which I see before me": Macbeth | 56 |
| "Is this all the thanks ---?" | 39 |
| "Is this all the thanks ___?" | 39 |
| "Is this being broadcast?" | 36 |
| "Is This It" garage rockers | 37 |
| "Is This Love" Corinne Bailey ___ | 43 |
| "Is this mic on?" | 27 |
| "Is this necessary?" | 30 |
| "Is this possible?" | 29 |
| "Is this really happening?" | 37 |
| "Is this really necessary?" | 37 |
| "Is this seat ___?" | 29 |
| "Is this some kind of ___?" | 37 |
| "Is this the spot?" | 29 |
| "Is this the thanks ___?" | 35 |
| "Is this thing on?" | 29 |
| "Is this thing on?," e.g. | 35 |
| "Is this too big a chance?" | 37 |
| "Is this what __ for ...?" | 36 |
| "Is this your idea of ___?" | 37 |
| "Is this your idea of ___?" ("I'm not amused") | 70 |
| "Is this your ___?" | 29 |
| "Is this your ___?" (magician's line) | 51 |
| "Is this __ time ... to talk of Pensions and Grenadiers?": Sterne | 75 |
| "Is this ___?" | 24 |
| "Is thy servant ___ . . . ?": II Kings 8:13 | 53 |
| "Is you is or is you ___ ma' baby?" | 49 |
| "Is You Is or Is You ___ My Baby?" (Louis Jordan song) | 64 |