| Prefix with state or change | 27 |
| Prefix with state or angle | 26 |
| Prefix with state or act | 24 |
| Prefix with state | 17 |
| Prefix with stat | 16 |
| Prefix with stasis | 18 |
| Prefix with starter | 19 |
| Prefix with star or bucks | 25 |
| Prefix with STANdard | 20 |
| Prefix with spore or sphere | 27 |
| Prefix with spore | 17 |
| Prefix with spherical | 21 |
| Prefix with sphere or system | 28 |
| Prefix with sphere or stich | 27 |
| Prefix with sphere or spore | 27 |
| Prefix with sphere or skeleton | 30 |
| Prefix with sphere or lateral | 29 |
| Prefix with sphere or disaster | 30 |
| Prefix with sphere and tourism | 30 |
| Prefix with sphere and politics | 31 |
| Prefix with sphere | 18 |
| Prefix with species | 19 |
| Prefix with speak that's, like, totally tubular | 51 |
| Prefix with space or stat | 25 |
| Prefix with space or naut | 25 |
| Prefix with space or dynamic | 28 |
| Prefix with space or café | 28 |
| Prefix with space | 17 |
| Prefix with sound | 17 |
| Prefix with sonic or violet | 27 |
| Prefix with sol or stat | 23 |
| Prefix with sol or space | 24 |
| Prefix with sol and stat | 24 |
| Prefix with sol | 15 |
| Prefix with soft or sweet | 25 |
| Prefix with sodium | 18 |
| Prefix with social or trust | 27 |
| Prefix with smoker | 18 |
| Prefix with slavery | 19 |
| Prefix with skirt or series | 27 |
| Prefix with skiing or sailing | 29 |
| Prefix with skid | 16 |
| Prefix with skeleton, scope or spore | 36 |
| Prefix with skeleton or thermal | 31 |
| Prefix with skeleton or spore | 29 |
| Prefix with skeleton or sphere | 30 |
| Prefix with skeleton or plasm | 29 |
| Prefix with skeleton | 20 |
| Prefix with sked or skid | 24 |
| Prefix with shock or treatment | 30 |
| Prefix with shipman | 19 |
| Prefix with ship or slip | 24 |
| Prefix with sexual | 18 |
| Prefix with sex or cycle | 24 |
| Prefix with sex | 15 |
| Prefix with septic or tank | 26 |
| Prefix with septic | 18 |
| Prefix with sensitive | 21 |
| Prefix with section | 19 |
| Prefix with sect or cycle | 25 |
| Prefix with sect | 16 |
| Prefix with second | 18 |
| Prefix with scope or style | 26 |
| Prefix with scope or skeleton | 29 |
| Prefix with scope or sclerosis | 30 |
| Prefix with scope or photo | 26 |
| Prefix with scope or phone | 26 |
| Prefix with scope or meter | 26 |
| Prefix with scope or logical | 28 |
| Prefix with scope | 17 |
| Prefix with sclerosis | 21 |
| Prefix with scient or potent | 28 |
| Prefix with science | 19 |
| Prefix with schooler | 20 |
| Prefix with school or war | 25 |
| Prefix with school or season | 28 |
| Prefix with school | 18 |
| Prefix with Saxon | 17 |
| Prefix with sanity, in 2012 buzz | 32 |
| Prefix with sailing | 19 |
| Prefix with saccharides | 23 |
| Prefix with sac or duct | 23 |
| Prefix with sac | 15 |
| Prefix with room or date | 24 |
| Prefix with room | 16 |
| Prefix with romantic | 20 |
| Prefix with rocket or fit | 25 |
| Prefix with rocket | 18 |
| Prefix with right or reader | 27 |
| Prefix with ribonucleic | 23 |
| Prefix with revisionist | 23 |
| Prefix with respect | 19 |
| Prefix with resort | 18 |
| Prefix with resin | 17 |
| Prefix with release | 19 |
| Prefix with relation | 20 |
| Prefix with region | 18 |
| Prefix with red or structure | 28 |
| Prefix with red | 15 |
| Prefix with realist | 19 |