| Creator of the film characters Harry and Sally | 46 |
| Creator of the first animated cartoon | 37 |
| Creator of the first crossword | 30 |
| Creator of the first designer perfume | 37 |
| Creator of the G.O.P. elephant | 30 |
| Creator of the game Missile Command | 35 |
| Creator of the Grinch | 21 |
| Creator of the heroine Catherine Earnshaw | 41 |
| Creator of the Hundred Acre Wood | 32 |
| Creator of the Imagine Peace Tower | 34 |
| Creator of the Joads | 20 |
| Creator of the Keystone Kops | 28 |
| Creator of the Koran | 20 |
| Creator of the label Obscure Records | 36 |
| Creator of the leitmotif | 24 |
| Creator of the Lorax | 20 |
| Creator of the Lost Boys | 24 |
| Creator of the March family | 27 |
| Creator of the March sisters | 28 |
| Creator of the Marches | 22 |
| Creator of the Marches in "Little Women" | 50 |
| Creator of the Mayfair Witches | 30 |
| Creator of the McDonald's empire | 36 |
| Creator of the Moffats | 22 |
| Creator of the Morlocks | 23 |
| Creator of the New Yorker's typeface ___ Irvin | 50 |
| Creator of the Once-ler | 23 |
| Creator of the Owl and the Pussy-cat | 36 |
| Creator of the Oz books | 23 |
| Creator of the pigs Old Major and Napoleon | 42 |
| Creator of the Poor Soul | 24 |
| Creator of the QB position | 26 |
| Creator of the Ragged Dick books | 32 |
| Creator of the Red Cross Knight | 31 |
| Creator of the religion Bokononism | 34 |
| Creator of the republican elephant | 34 |
| Creator of the robots Primus and Helena | 39 |
| Creator of the Schmoos | 22 |
| Creator of the SEC | 18 |
| Creator of the secretary Della | 30 |
| Creator of the Shmoos | 21 |
| Creator of the Sneetches | 24 |
| Creator of the Snopes family | 28 |
| Creator of the solid-body electric guitar, a model of which still bears his name | 80 |
| Creator of the stuff of legends? | 32 |
| Creator of the Tammany Hall tiger | 33 |
| Creator of the Tammany tiger | 28 |
| Creator of the Three Laws of Robotics | 37 |
| Creator of the Three Musketeers | 31 |
| Creator of the Ushers | 21 |
| Creator of the Winged Monkeys | 29 |
| Creator of the Zax | 18 |
| Creator of Thidwick | 19 |
| Creator of Thidwick the Big-Hearted Moose | 41 |
| Creator of Thor | 15 |
| Creator of Threepio | 19 |
| Creator of Tigger and Roo | 25 |
| Creator of Tobacco Rhoda | 24 |
| Creator of Tommy and Tuppence | 29 |
| Creator of Topsy | 16 |
| Creator of Torvald and Nora Helmer | 34 |
| Creator of Tristram Shandy | 26 |
| Creator of Truthful James | 25 |
| Creator of Tugboat Annie | 24 |
| Creator of TV's "Alias" | 37 |
| Creator of TV's island that "wasn't just an island" | 69 |
| Creator of U.P.C.'s | 23 |
| Creator of Uncle Remus | 22 |
| Creator of Wallace and Gromit | 29 |
| Creator of Walter Mitty | 23 |
| Creator of Wang and O-lan | 25 |
| Creator of Watson | 17 |
| Creator of Watson, a memorable 2011 "Jeopardy!" winner | 64 |
| Creator of Wildfell Hall | 24 |
| Creator of Willy Loman | 22 |
| Creator of Winnie the Pooh | 26 |
| Creator of Winston Smith | 24 |
| Creator of [circled letters] | 28 |
| Creator's sine qua non | 26 |
| Creator, in Caracas | 19 |
| Creator, in Cuzco | 17 |
| Creator, in Norse myth | 22 |
| Creator, redundantly | 20 |
| Creators | 8 |
| Creators of blurbs | 18 |
| Creators of booms | 17 |
| Creators of commercials | 23 |
| Creators of dins at inns | 24 |
| Creators of some highlights | 27 |
| Creators of Ulee's gold | 27 |
| Creature | 8 |
| Creature "cursed above all cattle" | 44 |
| Creature apt for this puzzle | 28 |
| Creature at SeaWorld | 20 |
| Creature Calvin often imagines himself to be | 44 |
| Creature catchers | 17 |
| Creature caught only by a virgin maiden | 39 |
| Creature comfort | 16 |
| Creature comfort? | 17 |
| Creature comforter? | 19 |