| Siouan people of the upper Missouri | 35 |
| Siouan language of the Carolinas | 32 |
| Sinusitis studier's specialty: Abbr. | 40 |
| Sinner's punishment, in the Bible | 37 |
| Sinn ___ (Irish political movement) | 35 |
| Sinks, as a ball inches from the hole | 37 |
| Sinking ship's call for help | 32 |
| Sinker or two-finger fastball, e.g. | 35 |
| Sinker of the frigate Abraham Lincoln | 37 |
| Sink outlet in a Persian Gulf nation? | 37 |
| Sinister-sounding Scandinavian goddess | 38 |
| Sinister-sounding daredevil name | 32 |
| Sinhalese is its official language | 34 |
| Singsongy comment in a sticky situation | 39 |
| Sings "The Lonely Goatherd" | 37 |
| Sings "Rock-a-Bye Baby" | 33 |
| Sings "'S Wonderful," say | 39 |
| Singles, compared to married people | 35 |
| Singles ad abbr. for "seekers" | 40 |
| Single-stranded cell substance, often | 37 |
| Single-serve coffee maker insert | 32 |
| Single-season RBI record-holder since 1930 | 42 |
| Single-named singer of the Velvet Underground | 45 |
| Single-named folk singer from Alabama | 37 |
| Single-named British R&B singer | 35 |
| Single-celled reproductive bodies | 33 |
| Single-celled organism with a flagellum | 39 |
| Single-bonded hydrocarbon functional group | 42 |
| Single word on the last line of a paragraph, say | 48 |
| Single white male who likes the cold? | 37 |
| Single parent with family values? | 33 |
| Single from Usher's "Confessions" | 47 |
| Single from "My Aim Is True" | 38 |
| Single from "I Am... Sasha Fierce" | 44 |
| Single from "Big Willie Style" | 40 |
| Single from "...And Justice for All" | 46 |
| Single for Metallica in 1989 and U2 in 1992 | 43 |
| Single computer instruction to replace many | 43 |
| Singing style popularized by Louis Armstrong | 44 |
| Singing style popular in the 1950s | 34 |
| Singing star loved by high-schoolers | 36 |
| Singing range for castrati, often | 33 |
| Singing mate of Stookey and Travers | 35 |
| Singing brothers of "Rag Mop" | 39 |
| Singing brothers in the 50's | 32 |
| Singing brother of Simon and Theodore | 37 |
| Singing brother of Joe, Gene and Vic | 36 |
| Singing brother of 60's-90's pop | 40 |
| Singing an olde-fashioned love song? | 36 |
| Singing a "Messiah" piece too quickly? | 48 |
| Singing "Me, me, me," e.g. | 36 |
| Singers Starr and Kiki look at each other | 41 |
| Singers Denny Doherty and John Phillips | 39 |
| Singer/songwriter with a famous bosom | 37 |
| Singer/songwriter known for nightwear? | 38 |
| Singer/songwriter Joe from the south, obviously | 47 |
| Singer/songwriter Corinne Bailey ___ | 36 |
| Singer/songwriter born Robert Zimmerman | 39 |
| Singer/songwriter born 3/12/1948 | 32 |
| Singer/actress McDonald with six Tony Awards | 44 |
| Singer/actress discovered by Mahalia Jackson | 44 |
| Singer/actress Deanna of the 1930s-'40s | 43 |
| Singer-songwriter's key-changing tool | 41 |
| Singer-songwriter born 11/22/1899 | 33 |
| Singer-song writer ("Piano Man") | 42 |
| Singer-athlete-actor: 1898–1976 | 38 |
| Singer-actor whose story is told in a 1946 film | 47 |
| Singer's twin who makes the cut? | 36 |
| Singer's suit-altering twin? | 32 |
| Singer's quick way to Scotland | 34 |
| Singer's name pronounced "Shar-day" | 49 |
| Singer's first syllables, perhaps | 37 |
| Singer's first recording, often | 35 |
| Singer's "___ Love": 1979 | 39 |
| Singer ___ "Paperboy" Reed | 36 |
| Singer Yusuf Islam, formerly ___ Stevens | 40 |
| Singer with the second video ever played on MTV | 47 |
| Singer with the hit "Foolish Games" | 45 |
| Singer with the first gold record single | 40 |
| Singer with the band Nine Stories | 33 |
| Singer with the album "Whiplash Smile" | 48 |
| Singer with the album "Starpeace" | 43 |
| Singer with the album "Shepherd Moons" | 48 |
| Singer with the album "Season of Glass" | 49 |
| Singer with the album "Remember Diana" | 48 |
| Singer with the album "Nick of Time" | 46 |
| Singer with the album "My World 2.0" | 46 |
| Singer with the album "Life for Rent" | 47 |
| Singer with the album "A Story" | 41 |
| Singer with the 2013 #1 hit "Roar" | 44 |
| Singer with the 2013 #1 "Royals" | 42 |
| Singer with the 2011 album '21' | 39 |
| Singer with the 2011 "Get $leazy" tour | 48 |
| Singer with the 2010 #1 hit "Tik Tok" | 47 |
| Singer with the 2009 hit "Tik Tok" | 44 |
| Singer with the 2009 #1 hit 'Tik Tok' | 45 |
| Singer with the 2007 hit "1234" | 41 |
| Singer with the 2004 album "Encore" | 45 |
| Singer with the 2002 hit "Ignition" | 45 |
| Singer with the 2001 album "Vespertine" | 49 |