| Comic strip eye, often | 22 |
| Comic strip favorite (with "The") | 43 |
| Comic strip featuring Jeremy and his teen friends | 49 |
| Comic strip featuring Jeremy Duncan | 35 |
| Comic strip featuring Popeye | 28 |
| Comic strip frame | 17 |
| Comic strip frames | 18 |
| Comic strip from Britain | 24 |
| Comic strip from England | 24 |
| Comic strip guy with an eye patch | 33 |
| Comic strip in which Popeye first appeared | 42 |
| Comic strip infant | 18 |
| Comic strip introduction of 1929 | 32 |
| Comic strip Kett | 16 |
| Comic strip magician | 20 |
| Comic strip makeup | 18 |
| Comic strip named for a dance | 29 |
| Comic strip opposites | 21 |
| Comic strip originally called "Li'l Folks" | 56 |
| Comic strip orphan | 18 |
| Comic strip outburst | 20 |
| Comic strip parts | 17 |
| Comic strip penguin | 19 |
| Comic strip penguin created by Berkeley Breathed | 48 |
| Comic strip pianist | 19 |
| Comic strip pinhead | 19 |
| Comic strip pooch | 17 |
| Comic strip populated by birds | 30 |
| Comic strip possum | 18 |
| Comic strip prince's son | 28 |
| Comic strip punches | 19 |
| Comic strip queen | 17 |
| Comic strip reaction | 20 |
| Comic strip reaction to a punch | 31 |
| Comic strip redhead | 19 |
| Comic strip retitled "The Piranha Club" in 1998 | 57 |
| Comic strip scream | 18 |
| Comic strip section | 19 |
| Comic strip segment | 19 |
| Comic strip set in Arkansas | 27 |
| Comic strip set in Coconino County | 34 |
| Comic strip shriek | 18 |
| Comic strip since '70 | 25 |
| Comic strip since 1932 | 22 |
| Comic strip sleuth who wears a deerstalker | 42 |
| Comic strip sound | 17 |
| Comic strip sound effect | 24 |
| Comic strip sound from a drunk person | 37 |
| Comic strip squeal | 18 |
| Comic strip teen Etta ___ | 25 |
| Comic strip that Chic Young abandoned to create "Blondie" | 67 |
| Comic strip that generated 23 books, with "The" | 57 |
| Comic strip that went from a daily to a weekly in 2007 | 54 |
| Comic strip tiger | 17 |
| Comic strip title character Andy | 32 |
| Comic strip title character whose last name is Flagston | 55 |
| Comic strip title character with the first name Augustus | 56 |
| Comic strip unit | 16 |
| Comic strip units | 17 |
| Comic strip Viking | 18 |
| Comic strip whose last collection was "Shoes: Chocolate for the Feet" | 79 |
| Comic strip whose title character is named Sonya Hobbs | 54 |
| Comic strip whose titular regent rules the land Myopia | 54 |
| Comic strip witch | 17 |
| Comic strip with an all-bird cast | 33 |
| Comic strip with Skeezix | 24 |
| Comic strip with the characters Rat and Pig | 43 |
| Comic strip with two naked main characters | 42 |
| Comic strip word | 16 |
| Comic strip worker | 18 |
| Comic strip written by Jerry Scott and illustrated by Jim Borgman | 65 |
| Comic strip's Eisenhower-parody slogan | 42 |
| Comic strip's Gump | 22 |
| Comic strongman | 15 |
| Comic superhero | 15 |
| Comic superheroes | 17 |
| Comic swamp dweller | 19 |
| Comic Sykes | 11 |
| Comic teenager since 1941 | 25 |
| Comic that comes to an end on October 3rd, and whose catchphrase ends this puzzle's theme answers | 101 |
| Comic theme | 11 |
| Comic Tina recovered from her wound? | 36 |
| Comic tribute | 13 |
| Comic turn | 10 |
| Comic TV actress | 16 |
| Comic unit | 10 |
| Comic verse | 11 |
| Comic Victor from Denmark | 25 |
| Comic vignette | 14 |
| Comic villain Luthor | 20 |
| Comic Wanda | 11 |
| Comic Wences | 12 |
| Comic who "jaws" at night | 35 |
| Comic who appeared as God on "Murphy Brown" | 53 |
| Comic who co-starred in "Nuns on the Run" | 51 |
| Comic who coined the term "domestic goddess" | 54 |
| Comic who coined the words "eneagled," "mantasy," and "freem" | 91 |
| Comic who declared "I'm not a liberal, I'm a radical!" | 72 |
| Comic who delivered the 2004 Harvard Class Day speech | 53 |
| Comic who had a 1950 sitcom | 27 |