| Sequence found in this puzzle's five longest answers | 56 |
| Sequence before W | 17 |
| Sequence before Friday's | 28 |
| Sequence associated with 6 | 26 |
| Sequence after JKL | 18 |
| Sequence | 8 |
| Sequel-to-a-sequel designation | 30 |
| Sequel-title word | 17 |
| Sequel, often | 13 |
| Sequel's tag, at times | 26 |
| Sequel's sequel | 19 |
| Sequel writer's work? | 25 |
| Sequel writer's other job? | 30 |
| Sequel words | 12 |
| Sequel word | 11 |
| Sequel with Streisand | 21 |
| Sequel to the Sammy Davis Jr. film "Salt and Pepper" | 62 |
| Sequel to Puzo's "The Last Don" | 45 |
| Sequel to Melville's "Typee" | 42 |
| Sequel to Kerouac's "On the Road" | 47 |
| Sequel to conviction | 20 |
| Sequel to Christopher Paolini's "Eragon" which Entertainment Weekly named "Worst Book of 2005" | 118 |
| Sequel to Buck's "The Good Earth" | 47 |
| Sequel to a store fire | 22 |
| Sequel to a Costner film? | 25 |
| Sequel to a 2013 3D film in which Manny Pacquiao spars in space? (Happy New Year to adolescent Jesus!) | 102 |
| Sequel to "Willard" | 29 |
| Sequel to "Typee" | 27 |
| Sequel to "Twilight" | 30 |
| Sequel to "Thriller" | 30 |
| Sequel to "The Omen" | 30 |
| Sequel to "The Good Earth" | 36 |
| Sequel to "The Beggar's Opera" | 44 |
| Sequel to "Puss in Boots"? | 36 |
| Sequel to "Mister Roberts" | 36 |
| Sequel to "Madame Bovary"? | 36 |
| Sequel to "Little Men" | 32 |
| Sequel to "Dad's Awakening" | 41 |
| Sequel to "Angela's Ashes" | 40 |
| Sequel to ''Typee'' | 35 |
| Sequel to ''The Good Earth'' | 44 |
| Sequel title words | 18 |
| Sequel title starter, sometimes | 31 |
| Sequel title starter | 20 |
| Sequel title start | 18 |
| Sequel title ender | 18 |
| Sequel that made The Onion A.V. Club's "Worst Movies of 2007" list, with a rare "F" grade | 113 |
| Sequel tag | 10 |
| Sequel set on the moon LV-426 | 29 |
| Sequel sequel | 13 |
| Sequel of 2007 | 14 |
| Sequel novel to "Typee" | 33 |
| Sequel letters | 14 |
| Sequel about the Dwarfs' reaction to a rash? | 48 |
| Sequel | 6 |
| Sepultures | 10 |
| Sepultura's '91 release | 31 |
| Sepultura song about a desire? | 30 |
| Sepulchre | 9 |
| Sepulchral structures | 21 |
| Sepulchral structure | 20 |
| Sepulchral sound | 16 |
| Sepulchers | 10 |
| Sepulcher | 9 |
| Septum? | 7 |
| Septuagenarian's next milestone | 35 |
| Septuagenarian's kitty, for short | 37 |
| Septuagenarian's goal | 25 |
| Septs | 5 |
| Septiembre, por ejemplo | 23 |
| Septiembre u octubre, por ejemplo | 33 |
| Septic tank worker? | 19 |
| Septic tank resident | 20 |
| Septic tank organism, e.g. | 26 |
| Septic tank bacterium, e.g. | 27 |
| Septic stuff | 12 |
| Septic or social starter | 24 |
| Septi- plus one | 15 |
| Septi minus one | 15 |
| Septets plus duets | 18 |
| Septets | 7 |
| Septet plus one | 15 |
| Septet on Hawthorne's house | 31 |
| Septet of Rome | 14 |
| Septet for Sinbad | 17 |
| Septennial sensation? | 21 |
| Septennial problem? | 19 |
| Septennial problem | 18 |
| Septennial occurrence | 21 |
| Septennial affliction? | 22 |
| Septennial affliction | 21 |
| Septembre's preceder | 24 |
| September's thirty | 22 |
| September's number | 22 |
| September ___ | 13 |
| September times | 15 |
| September time | 14 |
| September through April, to an oysterman | 40 |
| September through April, in a culinary guideline | 48 |
| September task in NYC for many world leaders | 44 |