| First volume of an encyclopedia, perhaps | 40 |
| First Western televised in color | 32 |
| First winner of a Best Animated Feature Oscar | 45 |
| First winner of consecutive Oscars | 34 |
| First woman director of the U.S. Mint | 37 |
| First woman director of U.S. Mint | 33 |
| First woman in the British Parliament | 37 |
| First woman in the House of Commons | 35 |
| First woman on the Supreme Court | 32 |
| First woman to be named Attorney General | 40 |
| First woman to fly across the Atlantic | 38 |
| First woman to host the Oscars solo | 35 |
| First woman to land a triple axel in competition | 48 |
| First woman to lead a seat-winning Federal Party | 48 |
| First woman to sit as a member of Parliament | 44 |
| First woman to sit in Parliament | 32 |
| First woman to swim the English Channel | 39 |
| First woman to teach at the Sorbonne | 36 |
| First woman to win Best Director | 32 |
| First word after a sneeze, often | 32 |
| First word in "Send in the Clowns" | 44 |
| First word in "The Banana Boat Song" | 46 |
| First word in "Would It Be Loverly?" | 46 |
| First word in a borough's name | 34 |
| First word in a celebratory song | 32 |
| First word in a celebratory song title | 38 |
| First word in a children's selection rhyme | 46 |
| First word in a D.H. Lawrence title | 35 |
| First word in a Dostoyevsky title | 33 |
| First word in a Ewan McGregor title | 35 |
| First word in a George Bush quote | 33 |
| First word in a Springsteen title | 33 |
| First word in a story from Clement Clarke Moore | 47 |
| First word in a tongue twister about seashells | 46 |
| First word in a Travolta film title | 35 |
| First word in a tropical drink name | 35 |
| First word in children's stories | 36 |
| First word in Connecticut's motto | 37 |
| First word in many a California city name | 41 |
| First word in many newspaper names | 34 |
| First word in Massachusetts' motto | 38 |
| First word in Montana's motto | 33 |
| First word in North Carolina's motto | 40 |
| First word in Oregon's motto | 32 |
| First word in the first crossword | 33 |
| First word in the Lord's Prayer | 35 |
| First word in the Treasure State's motto | 44 |
| First word in U2's "Vertigo" | 42 |
| First word learned by Helen Keller | 34 |
| First word of ''Cheek to Cheek'' | 48 |
| First word of ''Nowhere Man'' | 45 |
| First word of ''The Aeneid'' | 44 |
| First word of ''The Raven'' | 43 |
| First word of 'Send in the Clowns' | 42 |
| First word of "A Hard Day's Night" | 48 |
| First word of "A Lost Chord" | 38 |
| First word of "Aeneid" | 32 |
| First word of "Billie Jean" | 37 |
| First word of "Blowin' in the Wind" | 49 |
| First word of "Cheek to Cheek" | 40 |
| First word of "Citizen Kane" | 38 |
| First word of "Greensleeves" | 38 |
| First word of "Happiness Is a Warm Gun" | 49 |
| First word of "Home, Sweet Home" | 42 |
| First word of "Huckleberry Finn" | 42 |
| First word of "Jabberwocky" | 37 |
| First word of "Lycidas" | 33 |
| First word of "Marseillaise" | 38 |
| First word of "Nowhere Man" | 37 |
| First word of "Old Folks at Home" | 43 |
| First word of "Paul Revere's Ride" | 48 |
| First word of "Richard III" | 37 |
| First word of "Rock Around the Clock" | 47 |
| First word of "Scarborough Fair" | 42 |
| First word of "Send in the Clowns" | 44 |
| First word of "Stairway to Heaven" | 44 |
| First word of "The Aeneid" | 36 |
| First word of "The Raven" | 35 |
| First word of "The Waste Land" | 40 |
| First word of "Ulysses" | 33 |
| First word of "Winter Wonderland" | 43 |
| First word of "Wooly Bully" | 37 |
| First word of a 1968 movie title | 32 |
| First word of a Beatles song title | 34 |
| First word of a Beatles' album title | 40 |
| First word of a Clement Moore poem | 34 |
| First word of a Dickens-inspired band | 37 |
| First word of a famous Christmas poem | 37 |
| First word of a famous palindrome | 33 |
| First word of a famous song title | 33 |
| First word of a Frank McCourt title | 35 |
| First word of a kid's random selection ditty | 48 |
| First word of a Mozart opera title | 34 |
| First word of a New Year's song title | 41 |
| First word of a pre-Lenten celebration | 38 |
| First word of a Santa Claus story | 33 |
| First word of a Sarah Adams hymn | 32 |
| First word of a sentry's challenge | 38 |
| First word of a song sung once a year | 37 |
| First word of a southern celebration | 36 |