| Affirmative answer to a Mexican miss | 36 |
| Affirmative for Huckleberry Finn | 32 |
| Affirmative in ''Fargo'' | 40 |
| Affirmative that's an anagram of its synonym | 48 |
| Affirmed's 1978 Triple Crown archrival | 42 |
| Affix a "marked-down" label | 37 |
| Affix carelessly, with "on" | 37 |
| Affix, as some DIY shirt designs | 32 |
| Affixable with heat and pressure | 32 |
| Affixed like a "Kick Me" sign | 39 |
| Affixed one's John Hancock to | 33 |
| Affixes one's John Hancock to | 33 |
| Affleck employer in "Argo" | 36 |
| Affleck of "Armageddon" | 33 |
| Affleck of "Daredevil" | 32 |
| Affleck of "Pearl Harbor" | 35 |
| Affleck won a producer's Oscar for it | 41 |
| Affleck's 'Hollywoodland' role | 42 |
| Affleck's 2012 Oscar-winning film | 37 |
| Affleck/Lopez as a tabloid twosome | 34 |
| Afflicted with root rot, perhaps | 32 |
| Affliction a k a "blue devils" | 40 |
| Affliction FDR was diagnosed with | 33 |
| Affliction for Alice Cooper and DMX | 35 |
| Affliction formerly called the grippe | 37 |
| Affliction of one with a tin ear | 32 |
| Affliction said to be caused by worry | 37 |
| Affliction that broke out in 1966 | 33 |
| Affliction that may be helpful in a proposal? | 45 |
| Affliction whose name rhymes with its location | 46 |
| Afflictions known technically as hordeola | 41 |
| Affording grounds for a certain premium | 39 |
| Afghan leader before the Soviet invasion | 40 |
| Afghan Whigs song about being disliked? | 39 |
| Afghan Whigs song to greet a family member? | 43 |
| Afghanistan city on the Hari Rud | 32 |
| Afghanistan occupier, in the 1980s | 34 |
| Afghanistan's national airline | 34 |
| Afghanistan's Tora __ region | 32 |
| Afghanistan's Tora ___ region | 33 |
| Afghanistan's western neighbor | 34 |
| AFI Life Achievement Award winner | 33 |
| Afleet ___ (2005 Preakness and Belmont winner) | 46 |
| Afr. nation on the banks of the Limpopo | 39 |
| Afraid of only being an offensive player? | 41 |
| Afraid of running out, gas gauge-wise | 37 |
| Afraid to ask for a dance, maybe | 32 |
| Africa's fourth longest river | 33 |
| Africa's fourth-longest river | 33 |
| Africa's largest capital city | 33 |
| Africa's largest nation in area | 35 |
| Africa's largest nation, areawise | 37 |
| Africa's longest venomous snake | 35 |
| Africa's most populous capital city | 39 |
| Africa's most populous country | 34 |
| Africa's northernmost capital | 33 |
| Africa's second-longest river | 33 |
| Africa's seventh-largest country | 36 |
| Africa's third-largest country | 34 |
| Africa's third-longest river | 32 |
| Africa’s “Triumphant City” | 38 |
| African American Studies scholar Cornel | 39 |
| African American Vernacular English | 35 |
| African animal with zebralike legs | 34 |
| African antelope with twisted horns | 35 |
| African beast with a distinctive howl | 37 |
| African beasts with curved horns | 32 |
| African belief in sorcery and magic | 35 |
| African bird related to the starling | 36 |
| African capital nearest the Prime Meridian | 42 |
| African capital nicknamed Sunshine City | 39 |
| African capital on the Gulf of Guinea | 37 |
| African capital once known as Salisbury | 39 |
| African capital southwest of Kampala | 36 |
| African city where Yves St. Laurent was born | 44 |
| African city with famed botanical gardens | 41 |
| African civil war site of 1967-70 | 33 |
| African countries on the Mediterranean, e.g. | 44 |
| African country once known as Zaire | 35 |
| African country that was a French colony | 40 |
| African country with a namesake lake | 36 |
| African country with mountain gorillas | 38 |
| African country with no coastline | 33 |
| African ethnic and language group | 33 |
| African flower you don't have to pay for? | 45 |
| African heights, mentioned by Ptolemy | 37 |
| African immigrant in the Pyrenees? | 34 |
| African insect attracted to the color blue | 42 |
| African lake discovered by Livingstone | 38 |
| African lake spanning four countries | 36 |
| African landmark near the Mediterranean | 39 |
| African nation bordered by Mauritania | 37 |
| African nation or boy's name | 32 |
| African nation that practiced Mobutism | 38 |
| African nation with a crane on its flag | 39 |
| African nation with a green, yellow, and red flag | 49 |
| African nation's former name | 32 |
| African queen of old, familiarly | 32 |
| African region including Khartoum and Timbuktu | 46 |
| African region totaling 1.2 million square miles | 48 |