| ___-Spree Canal | 15 |
| ___-spirited | 12 |
| ___-speed bike | 14 |
| ___-specific | 12 |
| ___-Soviet relations | 20 |
| ___-Soviet | 10 |
| ___-soul (style of Erykah Badu and Lauryn Hill) | 47 |
| ___-soprano | 11 |
| ___-soluble (like some nutrients) | 33 |
| ___-Sol | 7 |
| ___-so | 6 |
| ___-snee (sPArring with knives) | 31 |
| ___-smock (cuckoo-flower) | 25 |
| ___-slipper (orchid) | 20 |
| ___-slipper | 11 |
| ___-slapper (good joke) | 23 |
| ___-slapper (funny joke) | 24 |
| ___-skin cap (Davy Crockett's hat) | 38 |
| ___-skiing | 10 |
| ___-ski party (lodge gathering, perhaps) | 40 |
| ___-ski (post-slopes relaxation) | 32 |
| ___-ski (post-schussing period) | 31 |
| ___-ski (lodge socializing) | 27 |
| ___-ski | 7 |
| ___-Sketch | 10 |
| ___-skelter | 11 |
| ___-size (big) | 14 |
| ___-Simon test | 14 |
| ___-Simbel, Egypt | 17 |
| ___-side up | 11 |
| ___-Siberian Railway | 20 |
| ___-Siberian Railroad | 21 |
| ___-shaped | 10 |
| ___-shanter (Scottish cap) | 26 |
| ___-shanter | 11 |
| ___-Shan, ship in Conrad's "Typhoon" | 50 |
| ___-serve (gas sign) | 20 |
| ___-serve | 9 |
| ___-serif (type style) | 22 |
| ___-serif | 9 |
| ___-Seltzer | 11 |
| ___-see | 7 |
| ___-seconds (Planck's constant unit) | 40 |
| ___-second violation | 20 |
| ___-sec (moderately sweet) | 26 |
| ___-Seal (leather protector) | 28 |
| ___-screen TV | 13 |
| ___-school (traditional) | 24 |
| ___-scarum (scatterbrain) | 25 |
| ___-scarum | 10 |
| ___-Saxon | 9 |
| ___-Saud | 8 |
| ___-san (water-conserving toilets and such) | 43 |
| ___-Saloon League | 17 |
| ___-Saint-Laurent (Quebec region) | 33 |
| ___-sahib | 9 |
| ___-Saens | 9 |
| ___-Sadr of Iran | 16 |
| ___-sac | 7 |
| ___-run (baseball ploy) | 23 |
| ___-rubber tree | 15 |
| ___-Royce | 9 |
| ___-Rooter (plumbing service) | 29 |
| ___-Rooter | 10 |
| ___-Romeo (Italian sports car) | 30 |
| ___-Romeo | 9 |
| ___-Roman wrestling | 19 |
| ___-Roman | 9 |
| ___-Romagna (region of Italy) | 29 |
| ___-Rollin, French politician: 1807–74 | 45 |
| ___-rod (flower of the lily family) | 35 |
| ___-rocket | 10 |
| ___-rock (musical genre) | 24 |
| ___-rock (music genre) | 22 |
| ___-rock | 8 |
| ___-robe (Calais closet) | 24 |
| ___-roaring | 11 |
| ___-Rivières, Quebec | 23 |
| ___-Rivières, Qué. | 24 |
| ___-Rivières, city in Canada | 31 |
| ___-ripper (romance novel) | 26 |
| ___-rich-quick scheme | 21 |
| ___-Rho (religious symbol) | 26 |
| ___-Rhin, France | 16 |
| ___-Rhin (Strasbourg's department) | 38 |
| ___-reviewed journals | 21 |
| ___-reviewed journal | 20 |
| ___-retentive | 13 |
| ___-relievo (kind of sculpture) | 31 |
| ___-relievo (high relief) | 25 |
| ___-relievo | 11 |
| ___-relief sculpture | 20 |
| ___-relief (sculpture style) | 28 |
| ___-relief | 10 |
| ___-red | 7 |
| ___-ready | 9 |
| ___-ray Discs | 13 |
| ___-ray Disc | 12 |
| ___-ray (HD movie option) | 25 |
| ___-ray (HD DVD rival, once) (3) | 32 |