| Unload, on Wall Street | 22 |
| Unload, pitch tents, etc. | 25 |
| Unload, with "off" | 28 |
| Unloaded truck's weight | 27 |
| Unlock Pandora's box | 24 |
| Unlock, to Shakespeare | 22 |
| Unlocked, as a computer file | 28 |
| Unlucky "numerus" | 27 |
| Unlucky accidents, old-style | 28 |
| Unlucky board game square | 25 |
| Unlucky board-game square | 25 |
| Unlucky British folksinger? | 27 |
| Unlucky catch, in cartoons | 26 |
| Unlucky gambler's note | 26 |
| Unlucky gambler's output | 28 |
| Unlucky investor's loss | 27 |
| Unlucky light-up combo? | 23 |
| Unlucky number for Augustus? | 28 |
| Unlucky number for Caesar? | 26 |
| Unlucky number on a match | 25 |
| Unlucky number, to Caesar? | 26 |
| Unlucky one's query | 23 |
| Unlucky one's question | 26 |
| Unlucky time for Caesar | 23 |
| UNLV basketball coach Kruger | 28 |
| Unmanned military craft | 23 |
| Unmarried lady, in Mex. | 23 |
| Unmarried woman's title | 27 |
| Unmarried woman, in Oaxaca | 26 |
| Unmemorable low-budget film | 27 |
| Unmerciful Athenian lawgiver | 28 |
| Unmitigated military leader? | 28 |
| Unmixed, to a mixologist | 24 |
| Unmoving machine parts | 22 |
| Unnamed author (abbr.) | 22 |
| Unnamed commercial product | 26 |
| Unnamed competitor, in ads | 26 |
| Unnamed others, briefly | 23 |
| Unnamed people or things | 24 |
| Unnatural blonde, e.g. | 22 |
| Unnatural blondes, e.g. | 23 |
| Unnatural morning spread | 24 |
| Unnatural, as hair color | 24 |
| Unnaturally blonde, e.g. | 24 |
| Unnaturally high voice | 22 |
| Unnavigable river of Russia | 27 |
| Unnecessary part of a jacket? | 29 |
| Uno + due + tre + quattro | 25 |
| Uno, dos, tres, -- ... | 22 |
| Unobtrusive attention getter | 28 |
| Unoccupied, as a theater seat | 29 |
| Unoccupied, as country | 22 |
| Unofficial advisers of a sort | 29 |
| Unofficial Aussie anthem | 24 |
| Unofficial discussions | 22 |
| Unofficial end of summer | 24 |
| Unofficial news source | 22 |
| Unofficial promissory note | 26 |
| Unofficial Seabees' motto | 29 |
| Unofficial ticket source | 24 |
| Unoiled robot's problem? | 28 |
| Unopened, as a wine bottle | 26 |
| Unopposed candidate: 1789 | 25 |
| Unoriginal newspaper worker? | 28 |
| Unorthodox debate stoppage | 26 |
| Unpaid babysitter, often | 24 |
| Unpaid babysitter, perhaps | 26 |
| Unpaid babysitters, maybe | 25 |
| Unpaid factory workers | 22 |
| Unpaid loan result, sometimes | 29 |
| Unpaid sitter, perhaps | 22 |
| Unpaid staffers, usually | 24 |
| Unpaired, as a chromosome | 25 |
| Unpaved edge of a road | 22 |
| Unpleasant face covering | 24 |
| Unpleasant information | 22 |
| Unpleasant interaction | 22 |
| Unpleasant issue to handle | 26 |
| Unpleasant party guest | 22 |
| Unpleasant political tactic | 27 |
| Unpleasant responsibility | 25 |
| Unpleasant rules to be under | 28 |
| Unpleasant site or sight | 24 |
| Unpleasant sound in nature | 26 |
| Unpleasant thing to eat | 23 |
| Unpleasant thing to evoke | 25 |
| Unpleasant thing to hit | 23 |
| Unpleasant thing to incur | 25 |
| Unpleasant thing to invoke | 26 |
| Unpleasant thing to step on | 27 |
| Unpleasant to be around | 23 |
| Unpleasant to the touch | 23 |
| Unpleasant type of mail | 23 |
| Unpleasant way to live | 22 |
| Unpleasant way to meet | 22 |
| Unpleasant, as a situation | 26 |
| Unpleasant, as details | 22 |
| Unpleasant, as weather | 22 |
| Unpleasant: Comb. form | 22 |
| Unpleasantly conspicuous | 24 |