| Up-and-___ (rising star) | 24 |
| Up-and-___ (promising rookie) | 29 |
| Up-and-down park fixture | 24 |
| Up-and-coming crappie? | 22 |
| Up-and-coming band's tape | 29 |
| Up-and-comers, perhaps | 22 |
| Up-and-comers with egos | 23 |
| Up-and-at-'em person | 24 |
| Up, with "up" | 23 |
| Up _______ (Ontario town) | 25 |
| Up ___ good (plotting evil) | 27 |
| Up ___ good (making trouble) | 28 |
| Up ___ alley (stymied) | 22 |
| Up ___ (extremely upset) | 24 |
| Up ___ (at a disadvantage) | 26 |
| Up with, with "of" | 28 |
| Up to, on some business signs | 29 |
| Up to, on a store sign | 22 |
| Up to, in classified ads | 24 |
| Up to ___ (acceptable) | 22 |
| Up to top physics standards? | 28 |
| Up to the time that, briefly | 28 |
| Up to the time of, informally | 29 |
| Up to the present time | 22 |
| Up to that time, poetically | 27 |
| Up to speed, musically | 22 |
| Up to one's old tricks | 26 |
| Up to one's neck (in) | 25 |
| Up to one's ears in | 23 |
| Up to one's ears (in) | 25 |
| Up to handling big burdens | 26 |
| Up to date, so to speak | 23 |
| Up to Camelot standards | 23 |
| Up the ___ without a paddle | 27 |
| Up the __ (in trouble) | 22 |
| Up the stakes, on eBay | 22 |
| Up the stakes, in a way | 23 |
| Up the river, in an acronym | 27 |
| Up the proverbial creek | 23 |
| Up the creek, so to speak | 25 |
| Up the creek without a paddle | 29 |
| Up on, with "of" | 26 |
| Up on, with "in" | 26 |
| Up on things, in the '40s | 29 |
| Up on the latest trends | 23 |
| Up on the latest gadgetry | 25 |
| Up on one's vocabulary | 26 |
| Up in the ___ (undecided) | 25 |
| Up in the air, perhaps | 22 |
| Up in the air, on schedules | 27 |
| Up in the air, on a sched. | 26 |
| Up in the air, for short | 24 |
| Up in the air figure?: Abbr. | 28 |
| Up in someone's business | 28 |
| Up in others' business | 26 |
| Up in everyone's business | 29 |
| Up for grabs, politically | 25 |
| Up for debate, as a bill | 24 |
| Up for being up to no good | 26 |
| Up close and personal? | 22 |
| Up and __ (on the move) | 23 |
| Up and down like a ___ | 22 |
| Uomo's counterpart | 22 |
| Unyielding, as the Old Guard | 28 |
| Unyielding rock singer? | 23 |
| Unyielding nucleus of a group | 29 |
| Unwritten, like a contract | 26 |
| Unwritten, as a contract | 24 |
| Unwrapped enthusiastically | 26 |
| Unworldly intellectual | 22 |
| Unwise thing to run from | 24 |
| Unwillingness, in rare usage | 28 |
| Unwillingness to yield | 22 |
| Unwillingness to boast | 22 |
| Unwilling to take credit | 24 |
| Unwilling to stay in line | 25 |
| Unwilling to negotiate | 22 |
| Unwilling to get organized | 26 |
| Unwilling to face reality | 25 |
| Unwilling to compromise | 23 |
| Unwilling listeners, usually | 28 |
| Unwilling fairy tale host | 25 |
| Unwilling blame-takers | 22 |
| Unwholesome atmosphere | 22 |
| Unwelcome word in surgery | 25 |
| Unwelcome word from a surgeon | 29 |
| Unwelcome windshield sights | 27 |
| Unwelcome water on a ship | 25 |
| Unwelcome visitors, sometimes | 29 |
| Unwelcome stocking stuffer | 26 |
| Unwelcome sound to a driver | 27 |
| Unwelcome sound for a burglar | 29 |
| Unwelcome sight on an apple | 27 |
| Unwelcome sight in the mail | 27 |
| Unwelcome roommate, perhaps | 27 |
| Unwelcome picnic guest | 22 |
| Unwelcome net receipts? | 23 |
| Unwelcome look, usually | 23 |
| Unwelcome letters from a bank | 29 |
| Unwelcome kitchen visitor | 25 |