| Sluggers' stats (Abbr.) | 27 |
| Slugging percentage, e.g. | 25 |
| Slugging percentage, for one | 28 |
| Sluggish from overeating | 24 |
| Sluggish from sedatives | 23 |
| Sluggish sci-fi gangster | 24 |
| Sluggish southern stream | 24 |
| Sluggish tree-dwellers | 22 |
| Sluggo's comics pal | 23 |
| Slugs that leave trails | 23 |
| Slum life documentarist | 23 |
| Slum reformer: 1849-1914 | 24 |
| Slum-clearance problem | 22 |
| Slum-clearing project, say | 26 |
| Slumber on a two-master? | 24 |
| Slumber party activity? | 23 |
| Slumber party challenge | 23 |
| Slumber party guest, often | 26 |
| Slumber-party attendee | 22 |
| Slumber-party favorite | 22 |
| Slumberer's rumbles | 23 |
| Slumgullion and burgoo | 22 |
| Slumgullion and goulash | 23 |
| Slumgullion and pepper pot | 26 |
| Slumgullion and pepperpot | 25 |
| Slumgullion or hasenpfeffer | 27 |
| Slumgullion or mulligan | 23 |
| Slumlord's building | 23 |
| Slump in one's seat | 23 |
| Slur over, as a syllable | 24 |
| Slur sufferer, in Soho | 22 |
| Slurp (with "up") | 27 |
| Slurpees' competitors | 25 |
| Slurps and burps, e.g. | 22 |
| Slurred over a syllable | 23 |
| Slurred over, as a syllable | 27 |
| Slurs over in pronunciation | 27 |
| Slush pile contents: Abbr. | 26 |
| Slush Puppie alternative | 24 |
| Slush Puppie lookalikes | 23 |
| Slush Puppie parent brand | 25 |
| Slush-pile pile: Abbr. | 22 |
| Sly call for attention | 22 |
| Sly's five-time costar | 26 |
| Sly's screen spouse | 23 |
| Slyly get one to enter | 22 |
| Slyly nasty, as a remark | 24 |
| Slyly seductive female | 22 |
| Sm., med. and lg., e.g. | 23 |
| Smack dab in the middle | 23 |
| Smack dab in the middle of | 26 |
| Smack hard, as a baseball | 25 |
| Smack with a book, e.g. | 23 |
| Smack-dab in the middle | 23 |
| Small "small" | 23 |
| Small "small"? | 24 |
| Small African antelope | 22 |
| Small African antelopes | 23 |
| Small African mongoose | 22 |
| Small agricultural enterprise | 29 |
| Small amount from a tube | 24 |
| Small amount of change | 22 |
| Small amount of Greek? | 22 |
| Small amount of liquid | 22 |
| Small amount of liquor | 22 |
| Small amount of residue | 23 |
| Small amount of solid food | 26 |
| Small amount of spirit? | 23 |
| Small amount or degree | 22 |
| Small amount, in Madrid | 23 |
| Small amount, informally | 24 |
| Small amount, slangily | 22 |
| Small amounts of smoke | 22 |
| Small amounts of sunscreen | 26 |
| Small amounts, as of cream | 26 |
| Small and charmingly spritely | 29 |
| Small and insignificant | 23 |
| Small and round, as eyes | 24 |
| Small and unimpressive | 22 |
| Small and unpretentious | 23 |
| Small antelope of Somaliland | 28 |
| Small apartment descriptor | 26 |
| Small apartments, in ads | 24 |
| Small arboreal primate | 22 |
| Small at-home business | 22 |
| Small attention-getter | 22 |
| Small Australasian parrots | 26 |
| Small Australian omnivore | 25 |
| Small Australian parrots | 24 |
| Small bag of chips, maybe | 25 |
| Small bags of scented powder | 28 |
| Small battery designation | 25 |
| Small bell's sound | 22 |
| Small beverage quantity | 23 |
| Small biological cavities | 25 |
| Small biological interstice | 27 |
| Small bird's chirp | 22 |
| Small bird's sound | 22 |
| Small birds, in British lingo | 29 |
| Small bit, as of cream | 22 |